Product logins

Find logins to all Clarivate products below.


Migraine (Prophylaxis) | Treatment Algorithms | Claims Data Analysis | US | 2018

According to DRG epidemiology, more than 35 million people in the United States suffer migraines. Migraine prophylaxis, though underused, is a core treatment approach to reduce migraine frequency, severity, and duration. Prescription options include a diverse mix of on- and off-label oral drugs, as well as Allergan’s Botox, approved specifically for chronic migraine. Prophylaxis is both individualized and dynamic as physicians adjust regimens to improve outcomes or avoid side effects. Understanding this patient journey provides needed context for new and existing players as next-generation preventives race to market.

Questions Answered

  • What patient share do key therapies and brands garner by line of therapy in migraine patients initiating prophylaxis? What are the quarterly trends in prescribing among recently treated and prophylactically naive migraine patients?
  • How has Botox been integrated into the treatment algorithm?
  • What proportion of prophylactically naive migraine patients receives preventive therapy within our prescription tracking period, and how quickly? What percentage of patients progress to later lines of therapy after initiating a prophylactic regimen?
  • What percentage of migraine patients are treated with prophylaxis monotherapy versus combination therapy? What are the most widely used combination therapies?
  • What are the product-level compliance and persistency rates among migraine patients treated with prescription prophylactic therapies?

Product Description

Treatment Algorithms: Claims Data Analysis provides detailed analysis of brand use across different lines of therapy using real-world patient-level claims data so that clients can accurately assess their source of business and quantify areas of opportunity for increasing their brand share.

Markets covered: United States

Real-world data: Longitudinal patient-level claims data analysis

Key drugs: Botox, topiramate IR, Trokeni XR, Qudexy XR, topiramate XR, propranolol, amitriptyline, verapamil, others

Key analysis provided:

  • Brand use across longitudinal patient sample.
  • Newly diagnosed patient analysis.
  • Treatment initiation and progression.
  • Line of therapy analysis.
  • Combination therapy analysis.
  • Source of business for recently treated patients.
  • Persistency and compliance analysis.
  • Product-level patient flowcharts.

Related Market Assessment Reports

Report
Gout – Current Treatment – Treatment Algorithms: Claims Data Analysis – Gout (US)
Gout, a form of inflammatory arthritis, arises due to the persistent elevation of serum uric acid (sUA) levels. The condition manifests through sudden and intense gout flares, causing significant…
Report
Scleroderma (Systemic Sclerosis) – Current Treatment – Treatment Algorithms: Claims Data Analysis – Scleroderma (Systemic Sclerosis) (US)
Scleroderma (systemic sclerosis) (SSc) is a rare progressive autoimmune disorder characterized by skin fibrosis, systemic inflammation, and vasculopathy that can manifest as Raynaud’s phenomenon…
Report
Hypertrophic Cardiomyopathy – Current Treatment – Treatment Algorithms: Claims Data Analysis – Hypertrophic Cardiomyopathy (US)
HCM is a genetic heart condition characterized by thickened myocardium and left ventricular hypertrophy, often linked to sarcomere mutations. While some patients remain asymptomatic, common…
Report
Non-Hodgkin’s Lymphoma and Chronic Lymphocytic Leukemia – Geographic Focus: China – Non-Hodgkin’s Lymphoma and Chronic Lymphocytic Leukemia – China In-Depth (China)
The NHL therapy market in China is poised for significant growth over the next decade, driven by the introduction of novel therapies and the continued uptake and label expansion of premium-priced…
Report
Breast Cancer – Geographic Focus: China – China In-Depth – Breast Cancer
The breast cancer therapy market in mainland China is one of the most dynamic in the oncology sector. Several new and emerging therapies are expected to gain approval for specific subpopulations,…