Hidradenitis Suppurativa | Treatment Algorithms: Claims Data Analysis | US | 2024

Hidradenitis suppurativa (HS) is a chronic, relapsing inflammatory disorder affecting hair follicles. It is characterized by the occurrence of inflamed and swollen lesions, which are typically painful and filled with fluid or pus. AbbVie’s Humira (adalimumab) was the only FDA-approved therapy for HS until October 2023, when Cosentyx received FDA approval for moderate to severe HS, the same subset of patients for which Humira is specifically approved. Notably, depending on their specific symptoms, patients may initially receive off-label treatment with other agents, such as antibiotics and immunosuppressants, before their physician prescribes these approved biologics. Alternative targeted therapies (e.g., Janssen’s Remicade [infliximab]) may also be used off-label in patients with more-severe disease and/or patients who do not respond to Humira or Cosentyx. This content will provide manufacturers of current HS treatments, as well as those developing novel agents, insight into the use of various drugs to treat the disease and market trends in the HS space.

QUESTIONS ANSWERED

• What patient shares do key therapies and brands garner by line of therapy in newly diagnosed HS patients? What are the quarterly trends in prescribing among recently treated and newly diagnosed HS patients?
• How has Humira been integrated into the treatment algorithm, and what is its source of business?
• What percentage of HS patients receive drug therapy within one year of diagnosis, and how quickly? What percentage of patients progress to later lines of therapy within one year of diagnosis?
• What percentage of HS patients are treated with monotherapy versus combination therapy? What are the most commonly used combinations?
• What are the product-level compliance and persistency rates among drug-treated patients?

PRODUCT DESCRIPTION

Treatment Algorithms: Claims Data Analysis provides detailed, quantitative analysis of the treatment journey and brand usage across lines of therapy and overall using real-world, patient-level claims data so that marketers can accurately assess their source of business, benchmark usage against competitors, and quantify areas of opportunity for their marketed or emerging brand.

Markets covered: United States

Key companies: AbbVie, Amgen, Janssen, Novartis, Eli Lilly, Sobi, Bausch Health, UCB, Sun Pharmaceuticals

Key drugs: Humira, infliximab biosimilars, Enbrel, Stelara, Simponi, clindamycin, doxycycline, acitretin, methotrexate, dapsone, cyclosporine, tacrolimus, Otezla, Cosentyx, Taltz, Tremfya, Skyrizi, Ilumya, Cimzia

Solution enhancement: The accompanying interactive dashboard provides novel delivery of data with interactive visuals, easier navigation, expanded analyses, and optional quarterly data refreshes.