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Revolutionary gene therapies for sickle cell pose challenges for payers

Revolutionary gene therapies for sickle cell pose challenges for payers

Casgevy™ and Lyfgenia™ are game-changers for patients with sickle cell disease (SCD). The first FDA-approved cell-based gene therapies for SCD, they come with multimillion-dollar list prices, posing a test for payers – and for the U.S. government’s new voluntary outcomes-based Cell and Gene Therapy Access Model.

This report, featuring proprietary Clarivate data and insights, examines the market access landscape surrounding these therapeutics, including:

  • Market share and growth
  • Value to price ratio
  • Cost and coverage challenges
  • Outcomes-based agreements
  • Payer coverage versus competitors
  • Adverse events
  • Company-sponsored patient access programs
  • Physician perceptions and barriers to prescribing