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Discovery and Translational Sciences Consulting

Expert-driven insights that unlock biology, optimize strategy, and advance patient outcomes

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Accelerate your research: unleash biological insights with expert precision

We accelerate discovery, preclinical, and translational research by solving complex challenges and uncovering insights. Powered by trusted data and advanced analytics, we bridge science and strategy to drive impact across the full drug discovery lifecycle.

400+ years of joint experience

across 30+ full-time PhD-level consultants located across both USA and Europe

250+ projects

have been delivered to Pharma and Biotech customers over the last 5 years

88% of clients recommend our services

trusted across Pharma and Biotech projects for delivering impactful, reliable solutions

Customized solutions designed to address your specific requirements

Our Consulting practice enables clients to make informed decisions across discovery, translational and clinical research for innovative, lifesaving therapies and technologies. We specialize in delivering comprehensive solutions tailored to meet your needs. Our services include:

Bioinformatics consulting

Omics analysis, biomarker and target discovery, indication expansion, drug repurposing, toxicity prediction and more.

Data management

FAIR-driven data curation, management, and integration to keep your data secure, accessible, and analysis-ready.

Guidance and training

Expert bioinformatics guidance and training to equip your team with the skills to maximize tools and techniques.

Deep understanding of the data to confidently advance research

We harness AI, ML, NGS, advanced bioinformatics, HPC, and Clarivate’s proprietary datasets to power discovery.

Precision discovery and translational insights

Unlock the full potential of your data with expert bioinformatics consulting services that drive smarter decisions in drug development and clinical research.

We leverage omics and clinical data to deliver actionable insights through advanced bioinformatics approaches, supporting biomarker discovery, patient stratification, and disease understanding.

Biomarker discovery and patient stratification
Analyse omics data to confidently stratify patients, monitor treatment efficacy and improve clinical trial design.
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Indication expansion
Systematically expand indication space for your assets considering biological mechanisms, competitive landscape and epidemiology of the disease across thousands of indications.
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Target identification and drug repurposing
Uncover new drug targets or new uses for established targets via custom network analysis using your data and our proprietary analytical workflows.
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Biological mechanism elucidation
Evaluate omics data to reconstruct biological mechanisms for disease understanding, target mechanism validation, toxic effect prediction and more.
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Clinical trial data analysis
Use efficient and powerful methods to draw meaningful conclusions from clinical and real-world data.
Disease Dossier
Accelerate innovation with our data-driven report integrating key insights on biomarkers, drug targets, pathways, therapies, and future trends for any disease.
Multi-omics analysis
Gain full insight into your omics data—genomics, proteomics, single-cell, spatial, metabolomics, microbiome, and more—to confidently drive your research forward.
Target assessment
Extract relevant information about a given target using insights from our manually curated databases.
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Predictive therapeutics & drug design

Accelerate your pipeline with AI-powered predictions and rational drug design.

Our consulting services enhance drug efficacy and safety through predictive modeling, combination strategies, and molecular design.

Drug design
Identify chemical modifications to compounds to improve activity profiles and safety while eliminating eventual toxicophores.
Drug combination prediction
Use cutting-edge predictive models to identify safe, effective drug synergies that boost patient outcomes, reduce side effects, and maximize therapeutic impact.
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Drug toxicity prediction
Utilize ML to predict success and failure of preclinical-stage drugs in clinical trials based on historic drug development data. 
Metabolite prediction
Identify potential drug metabolites early in drug discovery to assess safety, efficacy, predict metabolic pathways, and guide medicinal chemistry.
Antibody design
Leverage protein-protein interaction simulations to accelerate antibody design with improved binding affinity and specificity.

AI & computational platforms for drug discovery

Harness the power of AI and advanced computational biology to revolutionize R&D.

We provide cutting-edge platforms and algorithms to streamline discovery, optimize workflows, and generate novel insights.

Artificial intelligence
Evaluate, develop and apply AI models to all types of data in drug discovery and development.
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Biomedical Knowledge Graphs, data mining and integration
Create comprehensive source of biomedical knowledge spanning the entire R&D lifecycle.
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Systems Biology
Apply AI and advanced computational techniques to understand complex biological systems.
CBDD+: Computational Biology methods for Drug Discovery
Your systems biology toolkit - Implementation of the best advanced AI approaches
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ABC: Algorithm Benchmarking Consortium
Consortium model for systematic benchmarking of tools to ease algorithm and data selection
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Data management and custom solutions

We build robust, scalable bioinformatics solutions tailored to your research needs by developing custom tools, pipelines, and data management strategies using CDISC standards and workflow languages (e.g. Nextflow, WDL + Cromwell).

We leverage containerization (e.g. Docker) and deploy across platforms such as Domino, DNAnexus, and Seqera to ensure reproducibility, scalability, and regulatory compliance.

Data Management
Enhance data management using cutting-edge NLP techniques and FAIR principles, ensuring your data is Findable, Accessible, Interoperable, and Reusable for maximum efficiency and impact.
Custom pipeline and applications development
Tailored bioinformatics solutions (Pipelines, Reproducible data analyses / containerization, Interactive reports and visualizations, R shiny apps / dashboards, Custom packages, Databases).

Scientific writing, funding support and learning hub

Transform your science into impact with expert writing and grant support.

We help you communicate your research effectively and secure funding through compelling scientific narratives.

Scientific writing and grant proposal preparation
Craft compelling research narratives and winning grant proposals to maximize your funding success.
Abstract, manuscript composition and poster development
Communicate your findings clearly through expertly written abstracts, manuscripts, and visually engaging posters.
Personalized learning materials, training sessions and live demonstrations
Empower your team with tailored educational resources and hands-on scientific communication training.

Our clients

We deliver tailored bioinformatics solutions to diverse clients, driving innovation and better outcomes across sectors with deep domain expertise.

Pharmaceuticals

We help pharma companies accelerate drug discovery, development, and personalized medicine with insights that improve research, patient journeys, and outcomes.

Biotechnology

We partner with biotech firms to develop innovative solutions in gene editing, biomarker discovery, and synthetic biology—driving breakthroughs across applications.

Academic and Research Institutions

We provide bioinformatics support for research projects, grant applications, and publications.

Ready to transform your data into actionable insights?

Meet our team of experts, each bringing a wealth of experience in bioinformatics, systems biology, data science, and life sciences.

Meet our experts 3p

We’ve partnered with Clarivate’s bioinformatics services team for over 13 years. After evaluating multiple providers in 2012, Clarivate stood out—and continues to deliver exceptional scientific rigor and broad expertise. Their team plays a critical role in helping us prioritize targets, identify biomarkers, stratify patients, select indications, and uncover disease and drug mechanisms. Clarivate’s best-in-class content, deep scientific insight, and seamless collaboration make them a uniquely valuable partner in bioinformatics and predictive analytics.

Computational Biology Team Takeda Pharmaceutical Company

In a key preclinical RNA-seq study in cynomolgus monkeys, our initial analysis captured only 19.4% genome coverage—leaving critical data unusable. Clarivate re-analyzed the dataset, boosting coverage to 98.5% through a custom de novo transcriptome assembly and rigorous QC. Their expertise, clear communication, and tailored approach significantly enhanced the reliability of our results and confidence in the study.

Research Pharmacology Group Shire

Over two years, Clarivate has supported Takeda’s R&D in inflammation and autoimmune diseases through expert bioinformatics and computational biology consulting. Their strategic contributions —from indication expansion to single-cell transcriptomics— accelerated timelines and enhanced decision-making. The collaboration also included a public joint webinar on drug combination prediction. Clarivate is not just a vendor—they are a trusted partner in our scientific journey.

Director of Computational Biology Takeda Pharmaceutical Company

Clarivate collaborated on a comprehensive analysis of the skin microbiome, reviewing over 600 peer-reviewed studies and reprocessing publicly available datasets using a standardized bioinformatics pipeline. The result is a user-friendly interface that enables researchers to explore the aggregated data, uncover patterns of microbial composition, and distinguishing healthy skin from dysbiosis. We appreciate Clarivate’s scientific excellence, collaborative spirit, and commitment to making complex data accessible and actionable.

Principal Investigator S-Biomedic

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Our latest thought leadership

Explore our latest insights in thought leadership—featuring publications, blog posts, and webinars on key topics and cutting-edge research in the field.

Drug combinations: your questions answered Drug combinations: your questions answered
Blog November 19, 2024
Drug combinations: your questions answered

Developing drug combinations is a complex process with challenges and opportunities that can significantly impact patient outcomes. Diseases such as cancer often involve multiple molecular pathways, so single drugs may…

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Indication Expansion: Pioneering new uses for existing cancer drugs Indication Expansion: Pioneering new uses for existing cancer drugs
Blog May 31, 2024
Indication Expansion: Pioneering new uses for existing cancer drugs

Drug repurposing The process of de-novo drug discovery and development pipelines is both time-consuming and costly. It typically spans around 17 years and incurs costs exceeding $2 billion from the…

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Best practices for AI and ML use across the drug discovery and development lifecycle Best practices for AI and ML use across the drug discovery and development lifecycle
Blog November 23, 2023
Best practices for AI and ML use across the drug discovery and development lifecycle

The speed of drug discovery and development are being transformed by AI and machine learning applications. AI and life science companies need to conduct due diligence to ensure optimal results and avoid the pitfalls of AI capabilities.

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Drug repurposing, real world data and AI/ML: perspectives and opportunities Drug repurposing, real world data and AI/ML: perspectives and opportunities
Blog October 19, 2023
Drug repurposing, real world data and AI/ML: perspectives and opportunities

De-novo drug discovery and development pipelines are time-consuming and costly. It can take up to 17 years and cost more than $2 billion dollars from the discovery of a new…

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Machine learning combining multi-omics data and network algorithms identifies adrenocortical carcinoma prognostic biomarkers Machine learning combining multi-omics data and network algorithms identifies adrenocortical carcinoma prognostic biomarkers
Article
Machine learning combining multi-omics data and network algorithms identifies adrenocortical carcinoma prognostic biomarkers
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Comparing Phoneme Speech Recordings and Acoustic App Data Capture Experience for Android and iOS Mobile Device Users in the Large Decentralized AcRIS Study Comparing Phoneme Speech Recordings and Acoustic App Data Capture Experience for Android and iOS Mobile Device Users in the Large Decentralized AcRIS Study
Article
Comparing Phoneme Speech Recordings and Acoustic App Data Capture Experience for Android and iOS Mobile Device Users in the Large Decentralized AcRIS Study
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Best-in-class content

Leveraging our extensive proprietary content, we are uniquely positioned to extract deep insights and deliver unparalleled results for our clients.

CBDD

Computational biology methods for drug discovery

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Cortellis Drug Discovery Intelligence

Accelerate drug development with complete discovery and preclinical intelligence

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MetaBase & MetaCore

Accelerate drug discovery research

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OFF-X Translational Safety Intelligence

A unique translational tool providing drug and class safety intelligence to anticipate risks and drive new competitive value

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Cortellis Competitive Intelligence

Make critical portfolio decisions backed by comprehensive pipeline and pharma competitive intelligence

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Cortellis Clinical Trials Intelligence

Position your clinical trials for success from day one

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