Several effective anti-inflammatory agents and bronchodilators are available for controlling patients’ mild or moderate asthma. However, despite the entry of LAMAs (e.g., BI’s Spiriva) and novel biologics (e.g., AstraZeneca’s Fasenra, Teva’s Cinqair, Sanofi / Regeneron’s Dupixent, GSK’s Nucala) in the market, an unmet need remains for effective therapies for severe disease, especially for patients whose symptoms are not adequately controlled with current therapies or who depend on frequent SABA and/or oral corticosteroid use to achieve relief. This “Unmet Need” report provides quantitative insights into key treatment drivers and goals and the current level of unmet need in severe asthma, based on the perceptions of U.S. and European physicians. We analyze the commercial opportunities and how emerging therapies may capitalize on these opportunities.
United States, France, Germany, United Kingdom
Survey of approximately 30 U.S. pulmonologists, 30 U.S. allergists, and 30 European pulmonologists
Key Drugs Covered
Xolair, Nucala, Cinqair / Cinqaero, Fasenra, Dupixent, Spiriva (tiotropium), LABA / ICSFDCs
Key metrics included
“Unmet Need” supports clinical development decisions by identifying key attributes and assessing areas of unmet need for a specific disease or subpopulation. Based on surveys with U.S. and European physicians, this report provides insight into key treatment drivers and goals, the performance of current therapies, and the remaining commercial opportunities. One market scenario is profiled in detail by DRG experts, and additional customized market scenarios can be evaluated with the corresponding TPP simulator.