The atopic dermatitis (AD) market is poised to undergo a revolution owing to recent advances in understanding of disease pathology, the recent approval of topical crisaborole (Pfizer’s Eucrisa) in the United States, and the high-profile development of the first targeted AD biologic, dupilumab (Sanofi/Regeneron’s Dupixent). Although many treatments, both topical and systemic, are available for the treatment of atopic dermatitis, tremendous unmet need remains for therapies that treat severe, treatment-refractory atopic dermatitis. In this analysis, we assess the commercial opportunity that exists in the atopic dermatitis space through a comprehensive look at dermatologists’ treatment goals; the key efficacy, safety, and delivery attributes driving prescribing choice; the gaps in treatment left by current therapies; and the interplay of clinical and nonclinical attributes in determining the appeal of hypothetical new AD products.
Questions Answered:
Markets covered: United States, United Kingdom, France, Germany
Primary research: Survey of 60 U.S. and 30 European dermatologists fielded in January 2017
Key companies: Pfizer, Sanofi, Regeneron, Valeant, Astellas
Key drugs: Elidel, Eucrisa, Dupixent, Protopic