The schizophrenia therapy market is dominated by oral and long-acting injectable (LAI) antipsychotics, which are primarily effective in treating positive symptoms. However, in late 2019, the U.S. market saw the approval of a novel drug for schizophrenia—Intra-Cellular Therapies’ Caplyta (lumateperone)—and more therapies with novel mechanisms of action are in late-phase development, including Sumitomo Dainippon Pharma / Sunovion's SEP-363856. In addition, new oral and LAI antipsychotics (e.g., Alkermes’s ALKS3831, Janssen’s paliperidone palmitate six-month depot), as well as generics of some key branded agents (e.g., Sumitomo Dainippon Pharma / Sunovion’s Latuda), could launch in the near future. The availability of these new therapies may strongly influence treatment dynamics in schizophrenia.
DRG’s Special Topics reports assess key trends in dynamic disease areas. This report on schizophrenia will help drug marketers and developers gain needed insight into the anticipated impact of newer-to-market and key emerging therapies on physician prescribing decisions for schizophrenia in the United States.
Geographies: United States.
Primary research: Survey of 95 U.S. psychiatrists fielded in July 2020.
Key drugs covered: Caplyta, Secuado, ALKS3831, SEP-363856, pimavanserin, paliperidone palmitate six-month depot, Doria, TV-46000, Rexulti, Vraylar, Latuda, Abilify Maintena, Aristada, Invega Sustenna, Invega Trinza, Risperdal Consta, Perseris.
Key insights provided: