Clarivate Epidemiology's coverage of beta thalassemia (BT) comprises epidemiological estimates of key patient populations across the major mature pharmaceutical markets (the United States, France, Germany, Italy, Spain, the United Kingdom, and Japan). We report the prevalence of beta thalassemia for each country, as well as annualized case counts projected to the national population.
Clarivate Epidemiology's beta thalassemia forecast will answer the following questions:
How will changes in the levels of exposure to known risk or protective factors affect the number of people living with a diagnosis of beta thalassemia?
Of all people with beta thalassemia, how many in each country across the major mature pharmaceutical markets have been formally diagnosed?
How will demographic trends, such as population aging and improving life expectancy, affect the epidemiology of beta thalassemia over the forecast period?
All forecast data are available on the Clarivate Insights Platform in tabular format, with options to download to MS Excel. All populations are accompanied by a comprehensive description of the methods and data sources used, with hyperlinks to external sources. A summary evidence table generated as part of our systematic review of the epidemiological literature is also provided for full transparency into research and methods.
In total, Clarivate Epidemiology forecasts 30 beta thalassemia patient populations, as follows:
Diagnosed BT prevalent cases.
Diagnosed BT major prevalent cases.
Diagnosed BT intermedia prevalent cases.
Diagnosed B0/B0 BT major prevalent cases.
Diagnosed B0/B+ BT major prevalent cases.
Diagnosed B+/B+ BT major prevalent cases.
Diagnosed B0/B0 BT major prevalent cases with matched related HSC transplantation – younger than 12 years old.
Diagnosed B0/B0 BT major prevalent cases with matched related HSC transplantation – 12 years of age or older.
Diagnosed B0/B0 BT prevalent cases without matched related HSC transplantation – younger than 12 years old.
Diagnosed B0/B0 BT prevalent cases without matched related HSC transplantation – 12 years of age or older.
Literature review (studies included in / excluded from the analyses of beta thalassemia)
Diagnosed prevalence of beta thalassemia
Beta thalassemia by severity
Beta thalassemia major by genotype
Diagnosed prevalent cases of beta thalassemia major by HSC transplantation
Diagnosed prevalent cases of beta thalassemia intermedia by the need for transfusion
Drug-treated cases of beta thalassemia
Risk / protective factors applied to disease forecast models
Reference materials
Bibliography
Abbreviation table
Glossary
Deepika Chauhan
Deepika Chauhan, M.B.B.S., M.P.H., is an associate epidemiologist at Clarivate. Her focus is on oncology indications such as non-small-cell lung cancer, colorectal cancer, and gastric cancer. Prior to this role, she was an intern with DRG Analytics, where she worked with cross-functional teams to deliver analytical solutions to clients. Ms. Chauhan also worked at Drexel University as a research assistant on the EPA’s project to prevent Legionnaire’s disease in residential buildings. She graduated with an M.P.H. degree in epidemiology from Drexel University and holds a bachelor’s degree in medicine.
Stephanie Niquita Phankon
Stephanie Niquita Phankon, M.B.B.S., M.P.H., is a senior epidemiologist at Clarivate. She trained as a community physician and has supervised and coordinated various governmental and nongovernmental public health projects. She holds an M.P.H. specializing in epidemiology from the Tata Institute of Social Sciences in Mumbai and a medical degree from Hubei University of Chinese Medicine in the People’s Republic of China.
