Bladder Cancer and Upper Tract Urothelial Carcinoma | Disease Landscape & Forecast | G7 | 2022

Immune checkpoint inhibitors have greatly altered the treatment landscape for urothelial carcinoma. Initially confined to advanced disease, the anti-PD-1 therapies Keytruda (Merck & Co.) and Opdivo (Bristol Myers Squibb) are now approved for earlier treatment lines. The approval of Bavencio (Merck KGaA / Pfizer) as maintenance therapy for first-line locally advanced or metastatic urothelial carcinoma highlights the expanded use of immune checkpoint inhibitors in all lines of therapy. The regulatory approval of the antibody-drug conjugates Padcev (Seagen / Astellas) and Trodelvy (Gilead) has diversified the treatment paradigm for advanced and metastatic disease. Several new therapies and combinations anticipated to be approved by 2031 will only intensify the competition in this market.


  • What are the sizes of the clinically and commercially relevant drug-treatable bladder cancer and upper tract urothelial carcinoma populations, and how will drug-treatment rates change over time?
  • How is bladder cancer and UTUC currently treated? what are key differences in treatment between the two subtypes? What are the key advantages and disadvantages of existing drugs? What is the expected market impact of recent approvals?
  • Which of the emerging therapies are viewed as most promising, and what sales / uptake could they secure in the bladder cancer and UTUC market?
  • What are the key market drivers and constraints, and how will the market evolve over the 10-year forecast period?


Disease Landscape & Forecast provides comprehensive market intelligence with world-class epidemiology, keen insight into current treatment paradigms, in-depth pipeline assessments, and drug forecasts supported by detailed primary and secondary research.


Disease Landscape & Forecast will feature continual updates in 2022 to provide timely insights and analyses as meaningful indication-specific news and events unfold.

Additionally, Disease Landscape & Forecast introduces a new Drug Pipeline chapter with real-time, global pipeline intelligence content directly from Cortellis. This chapter is updated daily and features interactive figures that can be easily downloaded for detailed analysis or presentations.

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