The schizophrenia market is highly crowded given the presence of numerous antipsychotic therapies including the continued genericization of key oral therapies, the availability of newer oral atypical antipsychotics (e.g., Otsuka/Lundbeck’s Rexulti and Allergan/Gedeon Richter/Recordati’s Vraylar/Reagila), and the intensifying competition among long-acting injectables (LAIs). Indeed, to gain a foothold in the market, differentiation from already established therapies is a primary requirement for the late-phase and recently approved therapies—including new atypical antipsychotics (e.g., Alkermes’s ALKS-3831), new LAIs (e.g., Indivior’s Perseris, Janssen’s paliperidone six-month depot), and others (Intra-Cellular Therapies’ lumateperone, Minerva Neurosciences’ roluperidone, and Acadia Pharmaceuticals’ pimavanserin). Meanwhile, the potential of early- to mid-phase therapies for negative symptoms and cognitive impairment associated with schizophrenia, which are symptoms on which drug developers are increasingly focusing, remains to be seen.
Product Description: Disease Landscape & Forecast provides comprehensive market intelligence with world-class epidemiology, keen insight into current treatment paradigms, in-depth pipeline assessments, and drug forecasts supported by detailed primary and secondary research.
Geographies: United States, EU5, Japan.
Primary research: 38 country-specific interviews with thought-leading psychiatrists, supported by survey data collected for this and other DRG research.
Epidemiology: Diagnosed prevalence of schizophrenia by country, segmented by positive symptoms and negative symptoms; drug-treated prevalence of schizophrenia by country.
Forecast: Ten-year, annualized, drug-level sales and patient share of key schizophrenia therapies through 2027, segmented by brands/generics.
Emerging therapies: Phase III/PR: 10 drugs. Phase II: 18 drugs. Coverage of select preclinical and Phase I products.