The axial spondyloarthritis (AxSpA) market dynamics are constantly shifting. The definition of the disease, once limited to ankylosing spondylitis (AS), has expanded beyond those with spinal abnormalities detectable by radiography and into the population of nonradiographic (nr-AxSpA) patients. TNF-alpha inhibitors are the well-established biologics in AxSpA patients who do not respond to conventional therapies. The approval of the IL-17 inhibitor Cosentyx in the EU in 2015 marked the first non-TNF biologic for AS and the first drug with a new mechanism of action in over a decade. The launch of biosimilar TNF-alpha inhibitors, especially biosimilar etanercept in 2016 and biosimilar adalimumab in 2018, has and will continue to impact the market.
Geographies: France, Germany, Italy, Spain, United Kingdom.
Primary Research: Survey of 251 rheumatologists in France, Germany, Italy, Spain, and the United Kingdom.
Key Drugs Covered: Humira / biosimilar, Enbrel / biosimilar, Cimzia, Simponi, Remicade / biosimilar, Cosentyx.
Key insights provided: Factors influencing disease management and treatment decisions, drivers and constraints of treatment selection, physician-reported treatment practices and brand-level patient shares, rationale for changes in treatment approach, physician insight on persistency and compliance, and physician-reported recent / anticipated changes in brand usage or treatment approach.
Current Treatment: Physician Insights provides physician insights on treatment dynamics, prescribing behavior, and drivers of brand use so that marketers can create specific messaging around these treatment dynamics to more effectively increase or defend their market position.