Multiple Sclerosis – Geographic Focus: China – Multiple Sclerosis: China In-Depth (China)
Multiple sclerosis (MS), a chronic immune-mediated disease of the nervous system, is classified as a rare disease in China because of its low prevalence in that country. Traditionally, MS patients in China have been treated with disease-modifying therapies (DMTs) (IFN-β-1b [Bayer’s Betaferon], teriflunomide [Sanofi’s Aubagio], fingolimod [Novartis’s Gilenya], and siponimod [Novartis’s Mayzent]) and immunosuppressants (such as methotrexate, mitoxantrone, rituximab, azathioprine). In addition, the approval of ofatumumab (Novartis’s Kesimpta) and dimethyl fumarate (Biogen’s Tecfidera) in 2021 will boost the use of novel agents for the treatment of MS in China, thus increasing overall market sales. Despite the launch and availability of multiple DMTs in this market, pricing and reimbursement dynamics will continue to play a critical role in determining how the treatment paradigm will evolve over the next 10 years. Understanding these intersecting factors will be key to the success of current and future players in this market.
QUESTIONS ANSWERED
- What is the diagnosed prevalence of different clinical forms of MS, and how are these patients treated today? Do treatment management strategies differ between urban and rural China?
- Which are the most commercially relevant drugs in this market and why?
- What are interviewed experts’ insights into current treatment options?
- What are the key market access considerations, and how are they likely to impact the uptake of emerging therapies in this market?
- What are the key drivers and constraints in this market, and how will the market evolve over the forecast period?
PRODUCT DESCRIPTION
China In-Depth offers comprehensive market intelligence, including world-class epidemiology, keen insight into the China-specific access and reimbursement environment, current treatment paradigms, in-depth pipeline assessments, and drug forecasts supported by detailed primary and secondary research. This solution helps companies gauge commercial outlooks and optimize clinical development, subpopulation targeting, physician messaging, and overall long-term strategy in China.
Release date
March 2023
Geography
China
Primary research
Country-specific qualitative and quantitative insights driven by 5 thought-leader interviews and surveys with 50 neurologists.
Epidemiology
Diagnosed prevalence of MS (CIS, RR-MS, SP-MS, and PP-MS) in China, segmented by urban vs. rural; clinically relevant and market-relevant drug-treatable populations.
Forecast
10-year, annualized, drug-level sales and patient share of key MS therapies through 2032, based on primary and secondary market research to formulate bottom-up assumptions.
Emerging therapies
Phase III/PR: 5 drugs; Phase II: 4 drugs; Phase I: 3 drugs.
Chakradhar Reddy, B.Tech., Healthcare Research & Data Analyst, China-In-Depth. Mr. Reddy has several years’ experience in competitive intelligence and commercial analytics in the healthcare domain. Prior to joining Clarivate, he was an analyst in oncology and thought leadership at IQVIA. He holds a bachelor’s degree in genetic engineering from PRIST University in Thanjavur, India.
Navya Vardhan, M.Sc., Epidemiologist, Epidemiology. She obtained her M.Sc. in biostatistics and demography from the International Institute for Population Sciences in Mumbai. She also holds a B.Sc. in mathematics.