Male Hypogonadism | Treatment Algorithms | Claims Data Analysis | US | 2017

MARKET OUTLOOKLow testosterone is a condition characterized by impaired spermatogenesis and low serum testosterone. In adult men, low testosterone can be caused by intrinsic abnormalities in the testes or changes in pituitary or hypothalamic upstream signaling pathways contributing to testosterone biosynthesis. Age and comborbidity (e.g., obesity or T2D) driven declines in testosterone levels represent the majority of cases of low testosterone in adult men. TRT, which aims to increase overall serum testosterone levels, is the cornerstone therapy for low testosterone and is primarily administered via injection or topical means. However, a key drawback of TRTs is decreased spermatogenesis, and some alternative therapies for low testosterone focus on the stimulation of gonadotropins in effort to preserve fertility. Additionally, the FDA has recently cautioned against the use of TRT due to the possibility of increased cardiac risk, and this study will evaluate potential changes to physician prescribing and treatment strategies through real-world data analyses.QUESTIONS ANSWERED What patient share do key drug classes garner by line of therapy in newly diagnosed low testosterone patients? How have topical TRTs, injectable TRTs, and other miscellaneous TRT formulations been integrated into the treatment algorithm? What proportion of low testosterone patients receive drug therapy within a year of diagnosis, and how quickly? What percentage of patients progress to later lines of therapy within a year of diagnosis? What are the drug class-level compliance and persistency rates among drug-treated patients with low testosterone?PRODUCT DESCRIPTION Treatment Algorithms: Claims Data Analysis: provides detailed analysis of brand usage across different lines of therapy using real-world data patient-level claims data so you can accurately assess your source of business and quantify areas of opportunity for increasing your brand share.
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