Chronic sinusitis is prolonged inflammation of the paranasal sinuses that persists for more than 12 weeks despite treatment. Intranasal corticosteroids are typically used for treatment, followed by antibiotics or allergy medications, such as antihistamines, decongestants, leukotriene inhibitors, and anti-inflammatory agents. Although chronic sinusitis is one of the more-prevalent chronic illnesses in the United States, not many treatment options are available. Because no antibiotics are currently approved by the FDA to treat chronic sinusitis, otolaryngologists often prescribe antibiotics off-label based primarily on historical practice.
The report answers key questions including:
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