Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder characterized by alterations in motility, stool consistency and frequency, and urgency. It is generally classified into three subtypes: constipation predominant, diarrhea predominant, and mixed. Our analysis focuses on IBS-D, the diarrhea predominant subtype. Limited treatment options are currently available for IBS and only a few drugs have secured an FDA approval for IBS-D. Treatment options include antidepressants (off-label), motor stimulants (off-label), anticholinergic agents (off-label), a 5-HTR modulator (Sebela Pharmaceuticals’ Lotronex), and two recently approved agents: Salix Pharmaceuticals’ Xifaxan, an antibiotic, and Allergan’s Viberzi, an opioid delta receptor antagonist.
Treatment Algorithms: Claims Data Analysis provides detailed analysis of brand usage across different lines of therapy using real-world, patient-level claims data, so you can accurately assess your source of business and quantify areas of opportunity for increasing your brand share.