Conventional agents (e.g., immunosuppressants, 5-ASAs) have long been used to treat pediatric Crohn’s disease (CD). Among the TNF-α inhibitors, Janssen/Merck’s Remicade and AbbVie/Eisai’s Humira are the most commonly used biologics in moderate to severe pediatric CD. The newer drugs (i.e., Takeda’s Entyvio and Janssen’s Stelara), approved for adult CD, offer alternative treatment options, especially for TNF-α refractory patients; however, these drugs are not approved in pediatric CD. Still, given the limited treatment options for pediatric CD patients who fail TNF-α inhibitors, physicians may turn to these novel therapies for some patients. Indeed, the availability of these newer agents will likely make the treatment landscape more complex.
Treatment Algorithms: Claims Data Analysis provides detailed analysis of brand usage across different lines of therapy using real-world data patient-level claims data so you can accurately assess your source of business and quantify areas of opportunity for increasing your brand share.