Treatment of psoriatic arthritis (PsA) typically begins with conventional disease-modifying antirheumatic drugs (DMARDs), such as methotrexate, and progresses to more-potent biologics and/or targeted oral therapies as needed. The U.S. market for conventional DMARD-refractory PsA is crowded with multiple efficacious therapies, including six tumor necrosis factor-alpha (TNF-α) inhibitors, two interleukin (IL)-17 inhibitors, an IL-12/23 inhibitor, an IL-23 inhibitor, and two targeted oral agents (a PDE4 inhibitor and a JAK inhibitor). Additionally, the FDA approvals of another oral JAK inhibitor, Rinvoq (AbbVie), and a second-in-class IL-23 inhibitor, Skyrizi (AbbVie), have expanded physicians’ treatment armamentarium for PsA and increased competition among targeted therapies in this already cluttered market.
Treatment Algorithms: Claims Data Analysis provides detailed, quantitative analysis of the treatment journey and brand usage across lines of therapy and overall using real-world, patient-level claims data so that marketers can accurately assess their source of business, benchmark usage against competitors, and quantify areas of opportunity for their marketed or emerging brand.
Markets covered: United States
Key companies: AbbVie, Amgen, Janssen, Novartis, Eli Lilly, Pfizer, Sun Pharma, UCB
Key drugs: Humira, Enbrel, Remicade, biosimilar infliximab, Cimzia, Simponi, Simponi Aria, Stelara, Cosentyx, Taltz, Tremfya, Skyrizi, Orencia, Otezla, Xeljanz, Rinvoq, methotrexate
The accompanying interactive dashboard provides novel delivery of data with interactive visuals, easier navigation, expanded analyses, and optional quarterly data refreshes.