Multiple guidelines recommend treating post-traumatic stress disorder(PTSD) with psychotherapy first line. However, such approaches may not suffice for many patients, necessitating the use of pharmacological agents. Selective serotonin reuptake inhibitors (SSRIs) and other antidepressants are often used in the first line. Given the multiple symptom domains that affect PTSD patients, combination therapy with anxiolytics and benzodiazepines, as well as mood stabilizers, is widely used. Atypical antipsychotics may also be prescribed to patients who do not respond to prior lines of therapy. Given patients’ variable response rates and comorbid symptoms, treatment of PTSD follows a fragmented and individualized approach. In this report, we use national patient-level claims data to explore the use of key therapies for PTSD in both newly diagnosed and recently treated patients.
Treatment Algorithms: Claims Data Analysis provides detailed analysis of brand use across different lines of therapy using real-world patient-level claims data so that clients can accurately assess their source of business and quantify areas of opportunity for increasing their brand share.
Markets covered: United States
Real-world data: Longitudinal patient-level claims data analysis
Key companies: Allergan, Janssen, Lundbeck, Otsuka, Sunovion, Takeda
Key drugs: Latuda, Viibryd, Vraylar, Rexulti, Fetzima, Trintellix, aripiprazole, bupropion, escitalopram, anxiolytics/benzodiazepines, antiepileptic drugs, sertraline
Key analysis provided: