Major Depressive Disorder (DSM-V) – Current Treatment – Detailed, Expanded Analysis: Treatment Algorithms: Claims Data Analysis (US)
Major depressive disorder (MDD) is a highly drug-treated condition that uses an array of drug classes, including, but not limited to, selective serotonin reuptake inhibitors (SSRIs), selective serotonin and norepinephrine reuptake inhibitors (SNRIs), and—as adjunctive therapies—atypical antipsychotics. Although this drug market is ingrained with generic therapies, MDD patients’ heterogeneous response to current drugs and the need for additional efficacious therapies gives branded agents (e.g., Trintellix [Lundbeck/Takeda], Rexulti [Otsuka/Lundbeck], Vraylar [AbbVie], Spravato [Johnson & Johnson Innovative Medicine], Auvelity [Axsome Therapeutics]) the opportunity to be incorporated into the treatment algorithm. Given MDD’s highly competitive landscape encompassing both long-established and newer-to-market drugs, it is valuable for drug marketers and developers to understand physicians’ actual prescribing behavior in MDD. Our Treatment Algorithms study provides national patient-level claims data to explore the use of key therapies in both newly diagnosed and recently treated patients, providing insight into the current MDD treatment landscape.
Questions answered
- What patient shares do key therapies and brands garner by line of therapy in newly diagnosed MDD patients? What are the quarterly trends in prescribing among recently treated and newly diagnosed MDD patients?
- How have Trintellix, Rexulti, Vraylar, Spravato, and Auvelity been integrated into the treatment algorithm, and what are their sources of business?
- What percentage of MDD patients receive drug therapy within one year of diagnosis, and how quickly? What percentage of patients progress to later lines of therapy within one year of diagnosis?
- What percentage of MDD patients are treated with monotherapy vs. combination therapy? What are the most commonly used combinations?
- What are the product-level compliance and persistency rates among drug-treated patients?
Markets covered: United States.
Key companies: Lundbeck, Otsuka, Takeda, Johnson & Johnson Innovative Medicine, AbbVie, Axsome Therapeutics.
Key drugs: Trintellix, Rexulti, Vraylar, Spravato, Auvelity, escitalopram, sertraline, bupropion SR/XL, duloxetine, venlafaxine, quetiapine, trazodone.
Product description
Treatment Algorithms: Claims Data Analysis provides detailed, quantitative analysis of the treatment journey and brand usage across lines of therapy and overall using real-world, patient-level claims data so that marketers can accurately assess their source of business, benchmark usage against competitors, and quantify areas of opportunity for their marketed or emerging brand.
Key features
Dashboard featuring interactive visuals, easy navigation, and expanded analyses.
Table of contents
Soumya Soni, M.Tech., Healthcare Research & Data Analyst, CNS and Ophthalmology. Ms. Soni has substantial experience in market research, competitive intelligence, promotional intelligence, and consulting. She has produced multiple competitive intelligence-based landscape reports in oncology and contributed to ad-hoc market research projects. She also has experience in post-conference report preparation for key medical conferences such as AACR, ESMO, SITC, and ASH. Ms. Soni holds a master’s degree in biotechnology from Jaypee Institute of Information Technology in Noida, India.
Himanshu Jain, M.S.(Pharm.), Senior Manager, CNS and Ophthalmology. He has authored content for psychiatry and ophthalmology indications, including forecasting markets for schizophrenia, depression, and dry eye disease. He has about 15 years of experience working in market research and consulting firms. He earned his master’s degree in Pharmacology & Toxicology from the National Institute of Pharmaceutical Education and Research and holds an Executive Post-Graduate Diploma in International Business from the Indian Institute of Foreign Trade.