Clinical pathways, which establish optimal treatment protocols for specific patient populations based on the best evidence, have become increasingly prevalent in the treatment of cancer as payers and oncology practices seek to standardize best care and control costs. Breast cancer is among the cancers considered top priority for pathways programs. This report examines the application of clinical pathways for metastatic HER2+, HR+/HER2-, and triple-negative breast cancer therapies and explores payer reimbursement policies for current and emerging drugs and their impact on oncologists’ prescribing. The report also investigates the potential for reimbursement and oncologists’ likely uptake of biosimilars of trastuzumab (Herceptin).
Survey of 101 U.S. oncologists and 40 U.S. managed care organization (MCO) pharmacy and medical directors (PDs/MDs)
Key drugs covered
Current therapies: Afinitor, Avastin, Faslodex, Halaven, Herceptin, Ibrance, Kadcyla, Kisqali, Lynparza, Perjeta, Talzenna, Tykerb, Verzenio
Emerging therapies: alpelisib, margetuximab, tucatinib, Tecentriq
U.S. Access & Reimbursement provides in-depth insight on the impact of payer policy on prescribing behavior so that clients can build their market access strategy and optimize their brand positioning. This analysis of primary market research with physician specialists and U.S. payers helps clients stay up-to-date on restriction policies, gauge payer and prescriber attitudes toward specific therapies, identify opportunities where brands can capture patient share through market access, and maximize opportunities for emerging therapies by learning how previous brands gained favorable reimbursement or why they stumbled.