Dyslipidemia is an important modifiable risk factor for cardiovascular disease, which is one of the leading causes of death globally. Statins continue to dominate treatment of dyslipidemia, driven largely by strong physician familiarity and low cost owing to their widespread generic availability. With the positive outcomes data for certain nonstatin therapies, including Vascepa, PCSK9 inhibitors, and emerging therapies like bempedoic acid, the treatment paradigm is expected to evolve. However, the high prices of PCSK9 inhibitors and the resulting negotiations to reduce the prices of these novel agents highlight both physicians’ and payers’ preference for low-priced therapies.
Geography: United States
Primary research: Survey of 50 U.S. cardiologists and 50 U.S. endocrinologists and survey of 30 U.S. managed care organizations (MCO) pharmacy and medical directors (PDs / MDs)
Key drugs covered: Livalo, Vascepa, Repatha, and Praluent
Content highlights: Reimbursement and contracting; access and prescribing; special topics; opportunities and challenges for emerging therapies
U.S. Access & Reimbursement provides in-depth insight on the impact of payer policy on prescribing behavior so that clients can build their market access strategy and optimize their brand positioning. This analysis of primary market research with physician specialists and U.S. payers helps clients stay up-to-date on restriction policies, gauge payer and prescriber attitudes toward specific therapies, identify opportunities where brands can capture patient share through market access, and maximize opportunities for emerging therapies by learning how previous brands gained favorable reimbursement or why they stumbled.