Chronic Obstructive Pulmonary Disease – Access & Reimbursement – Detailed, Expanded Analysis (US) Inhaled COPD Therapies

Medicare beneficiaries with chronic obstructive pulmonary disease (COPD) have access to more than a dozen long-acting bronchodilator inhalers, ranging from blockbusters like GlaxoSmithKline’s (GSK’s) Advair,  AstraZeneca’s Symbicort, and Boehringer Ingelheim’s Spiriva to newer combination inhalers such as GSK’s Anoro Ellipta and Trelegy Ellipta (the first triple combination) and Boehringer Ingelheim’s Stiolto Respimat. Despite the competition, the cost of inhalers remains high, about $400-500 a month, presenting an affordability challenge particularly for seniors in high-deductible Medicare Advantage plans. Amid the recent entry of generic salmeterol / fluticasone, the COPD market is still developing as new products seek to improve efficacy, as well as dosing convenience. This report examines the reimbursement and prescribing environment for current and select emerging COPD drugs, with a special focus on patient affordability of inhalers in Medicare Advantage plans with prescription drug coverage (MAPD).

QUESTIONS ANSWERED

  • What attributes drive favorable reimbursement of branded inhalers on MCOs’ largest MAPDs and market uptake by pulmonologists, and how do generics impact the market?
  • How often are pulmonologists made aware of their patients’ difficulties in affording COPD therapy, and what are the negative effects on adherence and exacerbations?
  • What do managed care organization(MCO) directors consider the most feasible strategies to address the affordability issues facing Medicare members with COPD? What are the market-access prospects for AstraZeneca’s emerging Breztri Aerosphere if it is FDA-approved as the second triple-combination inhaler after GSK’s Trelegy?

Geography: United States

Primary research: Surveys of 100 U.S. pulmonologists and 41 U.S. MCO pharmacy and medical directors

Fingertip formulary: Formulary coverage data of COPD therapies by Medicare Advantage prescription drug plans covering 14.8 million lives nationally.

Key drugs covered: Advair, Symbicort, Dulera, Breo, AirDuo, Spiriva, Tudorza, Incruse, Seebri, Anoro, Stiolto, Bevespi, Utibron, Dualir, Trelegy, Breztri

Content highlights:

Reimbursement and contracting

Access and prescribing

Opportunities and challenges for emerging therapies

Disease-specific special topic

PRODUCT DESCRIPTION

U.S. Access & Reimbursement provides integrated brand- and disease-level insight on reimbursement dynamics and the impact of U.S. payer policy on physician prescribing behavior in the market access environment, including up-to-date analysis of drug coverage and restriction policies and payer and prescriber perspectives on key marketed drugs and receptivity to emerging therapies.

Table of contents

  • Chronic Obstructive Pulmonary Disease - Access & Reimbursement - Detailed, Expanded Analysis (US) Inhaled COPD Therapies
    • Access & Reimbursement COPD US April 2020

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