{"id":575803,"date":"2025-04-02T00:00:00","date_gmt":"2025-04-02T00:00:00","guid":{"rendered":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/epidim0044-biopharma-cystic-fibrosis-epidemiology-epidemiology-cystic-fibrosis-mature-markets\/"},"modified":"2026-03-31T10:26:37","modified_gmt":"2026-03-31T10:26:37","slug":"epidim0044-biopharma-cystic-fibrosis-epidemiology-epidemiology-cystic-fibrosis-mature-markets","status":"publish","type":"report","link":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/epidim0044-biopharma-cystic-fibrosis-epidemiology-epidemiology-cystic-fibrosis-mature-markets\/","title":{"rendered":"Cystic Fibrosis &#8211; Epidemiology &#8211; Epidemiology &#8211; Cystic Fibrosis &#8211; Mature Markets"},"content":{"rendered":"<p>Clarivate\u2019s Epidemiology\u2019s coverage of cystic fibrosis (<abbr title=\"cystic fibrosis\">CF<\/abbr>) comprises epidemiological estimates of key patient populations in 45 countries worldwide. We report both the incidence and prevalence of <abbr title=\"cystic fibrosis\">CF<\/abbr> for each country, as well as annualized case counts projected to the national population.<\/p>\n<p>Clarivate Epidemiology\u2019s <abbr title=\"cystic fibrosis\">CF<\/abbr> forecast will answer the following questions:<\/p>\n<ul class=\"round-bullets\">\n<li>How will improvements in survival change the number of people living with a diagnosis of <abbr title=\"cystic fibrosis\">CF<\/abbr>?<\/li>\n<li>Of all people diagnosed with <abbr title=\"cystic fibrosis\">CF<\/abbr>, how many in each country are drug-treated?<\/li>\n<li>How will demographic trends, such as population aging and improving life expectancy, affect the epidemiology of <abbr title=\"cystic fibrosis\">CF<\/abbr> over the forecast period?<\/li>\n<\/ul>\n<p><span patient populations are forecast over a period of years for the major mature pharmaceutical markets and other countries covered in this report.>All <\/span>for<span>ecast<\/span> data are available on Clarivate\u2019s Insights Platform in a tabular format, with options to download to <abbr data-abbreviation-entity=\"10739\" title=\"Microsoft\">MS<\/abbr> Excel. All populations are accompanied by a comprehensive description of the methods and data sources used, with hyperlinks to external sources. A summary evidence table generated as part of our systematic review of the epidemiological literature is also provided for full transparency into research and methods.<\/p>\n<p>In total, Clarivate Epidemiology forecasts 11 cystic fibrosis patient populations, as follows:<\/p>\n<ul class=\"round-bullets\">\n<li>Diagnosed incident cases of <abbr data-abbreviation-entity=\"6200\" title=\"cystic fibrosis\">C<\/abbr><abbr data-abbreviation-entity=\"6200\" title=\"cystic fibrosis\">F<\/abbr>.<\/li>\n<li>Diagnosed prevalent cases of <abbr data-abbreviation-entity=\"6200\" title=\"cystic fibrosis\">CF<\/abbr>.<\/li>\n<li>Diagnosed prevalent cases stratified by <abbr title=\"cystic fibrosis transmembrane conductance regulator\">CFTR<\/abbr> mutation.\n<ul class=\"round-bullets\">\n<li>Diagnosed F508del homozygous prevalent cases of <abbr data-abbreviation-entity=\"6200\" title=\"cystic fibrosis\">CF<\/abbr><\/li>\n<li>Diagnosed F508del heterozygous prevalent cases of <abbr data-abbreviation-entity=\"6200\" title=\"cystic fibrosis\">CF<\/abbr><\/li>\n<li>Diagnosed prevalent cases of <abbr data-abbreviation-entity=\"6200\" title=\"cystic fibrosis\">CF<\/abbr> negative or unknown for F508del mutation<\/li>\n<\/ul>\n<\/li>\n<li>Diagnosed prevalent cases stratified by <abbr title=\"forced expiratory volume in 1 second\">FEV1<\/abbr> status.\n<ul class=\"round-bullets\">\n<li>Diagnosed prevalent cases of <abbr data-abbreviation-entity=\"6200\" title=\"cystic fibrosis\">CF <\/abbr>of <abbr data-abbreviation-entity=\"5496\" title=\"forced expiratory volume in 1 second\">FEV1<\/abbr>  <\/li>\n<li>Diagnosed of prevalent cases of <abbr data-abbreviation-entity=\"6200\" title=\"cystic fibrosis\">CF <abbr data-abbreviation-entity=\"5496\" title=\"forced expiratory volume in 1 second\">FEV1<\/abbr><\/abbr><abbr data-abbreviation-entity=\"6200\" title=\"cystic fibrosis\"> <\/abbr> > 80<\/li>\n<li>Diagnosed prevalent cases of <abbr data-abbreviation-entity=\"6200\" title=\"cystic fibrosis\">CF <\/abbr>of <abbr data-abbreviation-entity=\"5496\" title=\"forced expiratory volume in 1 second\">FEV1<\/abbr> 40 to 80<\/li>\n<\/ul>\n<\/li>\n<li>Diagnosed prevalent cases stratified by airway pathogen.\n<ul class=\"round-bullets\">\n<li>Diagnosed prevalent cases of <abbr data-abbreviation-entity=\"6200\" title=\"cystic fibrosis\">CF<\/abbr> with chronic pseudomonas aeruginosa<\/li>\n<li>Diagnosed prevalent cases of <abbr data-abbreviation-entity=\"6200\" title=\"cystic fibrosis\">CF<\/abbr> with methicillin-resistant Staphylococcus aureus<\/li>\n<\/ul>\n<\/li>\n<li>Diagnosed drug-treated prevalent cases of <abbr data-abbreviation-entity=\"6200\" title=\"cystic fibrosis\">CF<\/abbr><\/li>\n<li>\u2026 and more (details available on request).<\/li>\n<\/ul>\n<p>Note: Coverage may vary by country.<\/p>\n","protected":false},"template":"","class_list":["post-575803","report","type-report","status-publish","hentry","report-gateway-biopharma","biopharma-therapy-areas-cystic-fibrosis","biopharma-therapy-areas-respiratory","biopharma-product-epidemiology","biopharma-date-2297"],"acf":[],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/575803","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report"}],"about":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/types\/report"}],"version-history":[{"count":1,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/575803\/revisions"}],"predecessor-version":[{"id":577521,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/575803\/revisions\/577521"}],"wp:attachment":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/media?parent=575803"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}