{"id":396645,"date":"2020-02-13T00:00:00","date_gmt":"2020-02-13T00:00:00","guid":{"rendered":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/exinim0003-2020-biopharma-cutaneous-lupus-erythematosus-executive-insights-us-2020\/"},"modified":"2026-04-22T05:23:38","modified_gmt":"2026-04-22T05:23:38","slug":"exinim0003-2020-biopharma-cutaneous-lupus-erythematosus-executive-insights-us-2020","status":"publish","type":"report","link":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/exinim0003-2020-biopharma-cutaneous-lupus-erythematosus-executive-insights-us-2020\/","title":{"rendered":"Cutaneous Lupus Erythematosus | Executive Insights | US | 2020"},"content":{"rendered":"<p><strong>MARKET OUTLOOK<\/strong><\/p>\n<p>Cutaneous lupus erythematosus (CLE) is a heterogeneous inflammatory autoimmune disease affecting the skin; discoid lupus erythematosus (DLE) is the most prevalent subtype of CLE. To date, no FDA-approved treatments are available for the treatment of CLE \/ DLE. The current treatment landscape involves off-label prescribing of calcineurin inhibitors, antimalarials, immunosuppressants, corticosteroids, and sometimes other drug classes, including biologics (e.g., rituximab, ustekinumab). The CLE pipeline holds an array of therapies with unique mechanisms of action, such as an anti-BDCA2 monoclonal antibody (Biogen\u2019s BIIB059), JAK inhibitors (LEO Pharma\u2019s delgocitinib and Gilead \/ Galapagos\u2019 filgotinib), and a Syk kinase inhibitor (Gilead \/ Galapagos\u2019 lanraplenib). If proven efficacious, these agents will enjoy a substantial commercial opportunity because of the high unmet need in this space.<\/p>\n<p><strong>QUESTIONS ANSWERED<\/strong><\/p>\n<ul>\n<li>What are the key areas of unmet need and opportunity in the CLE \/ DLE market?<\/li>\n<li>How are patients with CLE \/ DLE treated?<\/li>\n<li>What is the approximate size of the diagnosed prevalent CLE and DLE populations in the United States?<\/li>\n<li>What is the expected impact of novel therapies on the CLE \/ DLE market?<\/li>\n<li>What is the current market landscape and how will the landscape change in the in the future ?<\/li>\n<li>What are the key drivers of and constraints on the CLE market?<\/li>\n<\/ul>\n<p><strong>Geography<\/strong><\/p>\n<p>United States Primary Research 3 KOL interviews in January\u00a02020<\/p>\n<p><strong>Key COMPANIES Covered<\/strong><\/p>\n<p>Biogen, LEO Pharma, Gilead, Galapagos<\/p>\n<p><strong>Key Drugs Covered<\/strong><\/p>\n<p>Hydroxychloroquine, mycophenolate mofetil, Revlimid, BIIB059, delgocitinib, filgotinib, lanraplenib<\/p>\n<p><strong>PRODUCT DESCRIPTION<\/strong><\/p>\n<p>Executive Insights provides indication-specific market intelligence with world-class epidemiology, keen insight into current treatment paradigms, biotherapeutic pipelines, key clinical unmet needs, and competitive landscapes, supported by primary and secondary research. This solution provides succinct insights to any biopharma function or business professional looking to quickly grasp a new indication of interest.<\/p>\n","protected":false},"template":"","class_list":["post-396645","report","type-report","status-publish","hentry","report-gateway-biopharma","biopharma-geography-us","biopharma-date-942"],"acf":[],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/396645","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report"}],"about":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/types\/report"}],"version-history":[{"count":1,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/396645\/revisions"}],"predecessor-version":[{"id":396997,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/396645\/revisions\/396997"}],"wp:attachment":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/media?parent=396645"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}