{"id":391661,"date":"2014-05-01T00:00:00","date_gmt":"2014-05-01T00:00:00","guid":{"rendered":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/pcorcg6314-biopharma-multiple-sclerosis-pharmacor-g7-2014\/"},"modified":"2026-03-31T09:05:21","modified_gmt":"2026-03-31T09:05:21","slug":"pcorcg6314-biopharma-multiple-sclerosis-pharmacor-g7-2014","status":"publish","type":"report","link":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/pcorcg6314-biopharma-multiple-sclerosis-pharmacor-g7-2014\/","title":{"rendered":"Multiple Sclerosis | Pharmacor | G7 | 2014"},"content":{"rendered":"<p><em>Last Updated 1 May 2014<\/em><br \/>\nThe market for disease-modifying multiple sclerosis (MS) therapies is in the midst of transformation: three oral agents are now available\u2014fingolimod (Novartis\/Mitsubishi Tanabe Pharma\u2019s Gilenya\/Imusera), teriflunomide (Genzyme\u2019s\/Sanofi\u2019s Aubagio), and dimethyl fumarate (Biogen Idec\u2019s Tecfidera)\u2014alemtuzumab (Genzyme\/Sanofi\/Bayer HealthCare\u2019s Lemtrada) has reached the European market, and additional novel products and useful follow-ons are poised to launch. Over the next ten years, the wave of new product launches for the treatment of relapsing forms of MS will lead to meaningful shifts in an already complicated treatment algorithm and cause further fragmentation of the market. Meanwhile, drug developers have renewed their focus on identifying treatments for progressive forms of MS\u2014a perennially underserved population with few therapeutic options. The launch of premium-priced novel therapies, coupled with anticipated U.S. price increases, will drive a near-doubling of the market by 2018. Nevertheless, we expect that uptake of novel therapies will be tempered by a conservative prescriber base biased (at least initially) toward time-tested parenteral agents\u2014especially given the relative lack of long-term safety data and clinical experience with novel agents, as well as the absence of prognostic and theranostic markers needed to help guide tough treatment decisions. Last, the progressive introduction of generic and biosimilar competitors will mark a historic shift in this high-cost market as reimbursement authorities embrace the opportunity to lower drug-related healthcare expenditures in MS.<\/p>\n","protected":false},"template":"","class_list":["post-391661","report","type-report","status-publish","hentry","report-gateway-biopharma","biopharma-therapy-areas-multiple-sclerosis","biopharma-date-574"],"acf":[],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/391661","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report"}],"about":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/types\/report"}],"version-history":[{"count":1,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/391661\/revisions"}],"predecessor-version":[{"id":394784,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/391661\/revisions\/394784"}],"wp:attachment":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/media?parent=391661"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}