{"id":391147,"date":"2016-04-27T00:00:00","date_gmt":"2016-04-27T00:00:00","guid":{"rendered":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/unneid0001-2016-biopharma-gram-negative-infections-unmet-need-esbl-us-eu-2016\/"},"modified":"2026-03-31T09:02:16","modified_gmt":"2026-03-31T09:02:16","slug":"unneid0001-2016-biopharma-gram-negative-infections-unmet-need-esbl-us-eu-2016","status":"publish","type":"report","link":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/unneid0001-2016-biopharma-gram-negative-infections-unmet-need-esbl-us-eu-2016\/","title":{"rendered":"Gram-Negative Infections | Unmet Need | ESBL | US\/EU | 2016"},"content":{"rendered":"<p>The increasing prevalence and severity of Gram-negative infections (GNIs) caused by extended-spectrum beta-lactamase (ESBL)-producing pathogens have emerged as a global public health concern. Recent surveillance studies find that an increasing proportion of ESBL-producing pathogens are also associated with resistance to other classes of antibiotics, further limiting therapeutic options. As such, new antibiotics with activity against ESBL-producing Gram-negative pathogens represent a key unmet need in the GNI therapy market.<\/p>\n","protected":false},"template":"","class_list":["post-391147","report","type-report","status-publish","hentry","report-gateway-biopharma","biopharma-therapy-areas-infectious-disease","biopharma-product-unmet-need","biopharma-geography-us","biopharma-date-858"],"acf":[],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/391147","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report"}],"about":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/types\/report"}],"version-history":[{"count":1,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/391147\/revisions"}],"predecessor-version":[{"id":394270,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/391147\/revisions\/394270"}],"wp:attachment":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/media?parent=391147"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}