{"id":390733,"date":"2018-03-05T00:00:00","date_gmt":"2018-03-05T00:00:00","guid":{"rendered":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/algoim0041-2018-biopharma-systemic-lupus-erythematosus-treatment-algorithms-claims-data-analysis-us-2018\/"},"modified":"2026-04-22T23:28:03","modified_gmt":"2026-04-22T23:28:03","slug":"algoim0041-2018-biopharma-systemic-lupus-erythematosus-treatment-algorithms-claims-data-analysis-us-2018","status":"publish","type":"report","link":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/algoim0041-2018-biopharma-systemic-lupus-erythematosus-treatment-algorithms-claims-data-analysis-us-2018\/","title":{"rendered":"Systemic Lupus Erythematosus | Treatment Algorithms | Claims Data Analysis | US | 2018"},"content":{"rendered":"<p>Systemic Lupus Erythematosus (<abbr data-original-title=\"systemic lupus erythematosus\" title=\"\">SLE<\/abbr>) is an autoimmune disease that affects multiple organ systems of the body, and its symptoms range from general malaise to serious,\u00a0<abbr data-original-title=\"central nervous system\" title=\"\">CNS<\/abbr>\u00a0and renal manifestations. Currently, there are limited treatment options available to treat the condition. Corticosteroids, hydroxychloroquine, and conventional immunosuppressants are the mainstay of treatment for\u00a0<abbr data-original-title=\"systemic lupus erythematosus\" title=\"\">SLE<\/abbr>. However, many patients fail to respond to these therapies and\/or experience significant adverse events, and clinicians utilize other agents including Benlysta (the only biologic indicated for\u00a0<abbr data-original-title=\"systemic lupus erythematosus\" title=\"\">SLE<\/abbr>) and Rituxan (off-label).<\/p>\n<p>The Treatment Algorithms: Claims Data Analysis report examines physicians\u2019 actual prescribing behavior as they initiate therapy and move through second- and third-line choices. Our analysis is supported by a deep longitudinal patient-level claims dataset and provides a representative sample of\u00a0<abbr data-original-title=\"United States\" title=\"\">U.S.<\/abbr>\u00a0treatment practice for Medicare supplemental and commercially insured patients.<\/p>\n<p><strong>Questions answered:<\/strong><\/p>\n<ul>\n<li>Which therapies capture the top patient share in different lines of therapies for both newly diagnosed and recently treated patients?<\/li>\n<li>What proportion of\u00a0<abbr data-original-title=\"systemic lupus erythematosus\" title=\"\">SLE<\/abbr>\u00a0patients receive drug therapy within one year of diagnosis, and how quickly? What percentage of patients progress to later lines of therapy within one year of diagnosis?<\/li>\n<li>Which therapies are used alone and which ones are used in combination? What are the most widely used combination therapies?<\/li>\n<li>What percentage of newly diagnosed patients on key\u00a0<abbr data-original-title=\"systemic lupus erythematosus\" title=\"\">SLE<\/abbr>\u00a0therapies add or switch to new agents as they move through lines of treatment?<\/li>\n<li>What are the persistency and compliance rates for key\u00a0<abbr data-original-title=\"systemic lupus erythematosus\" title=\"\">SLE<\/abbr>\u00a0therapies?<\/li>\n<\/ul>\n","protected":false},"template":"","class_list":["post-390733","report","type-report","status-publish","hentry","report-gateway-biopharma","biopharma-therapy-areas-systemic-lupus-erythematosus","biopharma-product-treatment-algorithms-claims-data-analysis","biopharma-geography-us","biopharma-date-920"],"acf":[],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/390733","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report"}],"about":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/types\/report"}],"version-history":[{"count":1,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/390733\/revisions"}],"predecessor-version":[{"id":393857,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/390733\/revisions\/393857"}],"wp:attachment":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/media?parent=390733"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}