{"id":390696,"date":"2018-04-26T00:00:00","date_gmt":"2018-04-26T00:00:00","guid":{"rendered":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/unnecg0018-2018-biopharma-interstitial-cystitis-unmet-need-us-eu-2018\/"},"modified":"2026-04-27T11:27:51","modified_gmt":"2026-04-27T11:27:51","slug":"unnecg0018-2018-biopharma-interstitial-cystitis-unmet-need-us-eu-2018","status":"publish","type":"report","link":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/unnecg0018-2018-biopharma-interstitial-cystitis-unmet-need-us-eu-2018\/","title":{"rendered":"Interstitial Cystitis | Unmet Need | US\/EU | 2018"},"content":{"rendered":"<p>Interstitial cystitis\/bladder pain syndrome (ICBPS) is a disorder characterized by chronic pain, discomfort, and pressure in the pelvic region that often includes symptoms of urinary frequency and urgency. Janssen\/bene-Arzneimittel\u2019s\u00a0Elmiron and Mylan\u2019s\u00a0intravesical dimethyl sulfoxide (RIMSO-50) are the only two pharmacological treatments approved for ICBPS, but other antihistamines, antidepressants, and antiepileptics\u00a0may be\u00a0used off-label to ameliorate symptoms. Because pharmacological treatments are usually only partially effective, they are often combined with nonpharmacological therapies in a trial-and-error approach. As such, substantial unmet need persists for more effective treatment options.<\/p>\n<p><strong>QUESTIONS ANSWERED<\/strong><\/p>\n<ul>\n<li>What are the treatment drivers and goals for ICBPS?<\/li>\n<li>What drug attributes are key influencers, which have limited impact, and which are hidden opportunities?<\/li>\n<li>How do current therapies perform on key treatment drivers and goals for ICBPS?<\/li>\n<li>What are the prevailing areas of unmet need and opportunity in ICBPS?<\/li>\n<li>What trade-offs across different clinical attributes and price are acceptable to U.S. and European urologists for a hypothetical new ICBPS drug?<\/li>\n<\/ul>\n<p><strong>PRODUCT DESCRIPTION<\/strong><\/p>\n<p>Unmet Need: Provides quantitative insight into U.S. and European physician perceptions of key treatment drivers and goals and the current level of unmet need for a specific disease. Commercial opportunities are analyzed, and the extent to which emerging therapies may capitalize on these opportunities is evaluated.<\/p>\n<p><strong>Markets covered:<\/strong> United States, United Kingdom, France, Germany.<\/p>\n<p><strong>Primary research: <\/strong>Survey of 60 U.S. and 30 European urologists fielded in March 2018.<\/p>\n<p><strong>Key companies: <\/strong>bene-Arzneimittel, Janssen,\u00a0Mylan, Pfizer.<\/p>\n<p><strong>Key drugs: <\/strong> Elmiron, amitriptyline, hydroxyzine, duloxetine, Lyrica, gabapentin, intravesical medications (lidocaine, heparin, dimethyl sulfoxide, hyaluronic acid, others).<\/p>\n<p><strong>Key metrics included:<\/strong><\/p>\n<ul>\n<li>Stated versus derived analysis of U.S. and European physician prescribing behavior.<\/li>\n<li>Conjoint analysis with U.S. and European physicians, including market simulator.<\/li>\n<li>Assessment of current drug performance against treatment drivers and goals.<\/li>\n<li>Physician perceptions of unmet need in disease\/subpopulation covered and related diseases\/subpopulations.<\/li>\n<\/ul>\n","protected":false},"template":"","class_list":["post-390696","report","type-report","status-publish","hentry","report-gateway-biopharma","biopharma-therapy-areas-chronic-pain","biopharma-product-unmet-need","biopharma-geography-us","biopharma-date-920"],"acf":[],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/390696","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report"}],"about":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/types\/report"}],"version-history":[{"count":1,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/390696\/revisions"}],"predecessor-version":[{"id":393820,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/390696\/revisions\/393820"}],"wp:attachment":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/media?parent=390696"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}