{"id":390593,"date":"2018-09-06T00:00:00","date_gmt":"2018-09-06T00:00:00","guid":{"rendered":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/cutrim0024-2018-biopharma-systemic-lupus-erythematosus-current-treatment-physician-insights-systemic-lupus-erythematosus\/"},"modified":"2026-04-23T11:39:11","modified_gmt":"2026-04-23T11:39:11","slug":"cutrim0024-2018-biopharma-systemic-lupus-erythematosus-current-treatment-physician-insights-systemic-lupus-erythematosus","status":"publish","type":"report","link":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/cutrim0024-2018-biopharma-systemic-lupus-erythematosus-current-treatment-physician-insights-systemic-lupus-erythematosus\/","title":{"rendered":"Systemic Lupus Erythematosus | Current Treatment: Physician Insights | Systemic Lupus Erythematosus (Excluding Active Lupus Nephritis and Severe CNS Manifestations) | US | 2018"},"content":{"rendered":"<p><strong>MARKET OUTLOOK<\/strong><\/p>\n<p>SLE is an autoimmune disease characterized by varied symptoms ranging from general fatigue to serious organ manifestations. Options available to treat SLE are limited, with hydroxychloroquine, corticosteroids, and immunosuppressants as the mainstays of treatment. However, not all patients respond to these therapies and many report significant adverse events; in these patients, physicians\u00a0administer biologics, such as GlaxoSmithKline\u2019s Benlysta (the only biologic approved for SLE) and Genentech\/Biogen\u2019s Rituxan (used off-label). \u201cSystemic Lupus Erythematosus\u00a0 (excluding active lupus nephritis and severe CNS manifestations) Current Treatment\u201d content offers valuable insights into treatment algorithm of the disease, physician prescribing behavior, and patient share dynamics of current therapies used to treat lupus nephritis. Better understanding of patient treatment pathways and drivers of physicians\u2019 treatment decisions can help elucidate physician preferences and patient share dynamics for\u00a0these agents as well as provide valuable insights for manufacturers of novel brands coming to market.<\/p>\n<p><strong>QUESTIONS ANSWERED<\/strong><\/p>\n<ul>\n<li>What patient share do key drug classes and individual therapies garner in mild, moderate, and severe SLE (excluding severe lupus nephritis and severe CNS manifestations)?<\/li>\n<li>Which main factors influence treatment practices in SLE (excluding severe lupus nephritis and severe CNS manifestations)? What is the sequencing of treatment in this patient population? What do physicians report as recent and anticipated changes in their treatment practices?<\/li>\n<li>Which features drive the choice of a therapy for SLE without severe lupus nephritis and severe CNS manifestations? What are the key barriers in prescribing of SLE therapies?<\/li>\n<li>What are the compliance and persistency rates for key SLE therapies?<\/li>\n<\/ul>\n<p><strong>PRODUCT DESCRIPTION<\/strong><\/p>\n<p>Current Treatment: Physician Insights provides physician insights on treatment dynamics, prescribing behavior, and drivers of brand use so you can create specific messaging around these treatment dynamics in order to more effectively increase or defend your market position.<\/p>\n<p><strong>GEOGRAPHIES<\/strong><\/p>\n<p>United States.<\/p>\n<p><strong>PRIMARY RESEARCH<\/strong><\/p>\n<p>Survey of\u00a0102\u00a0rheumatologists in the United States.<\/p>\n<p><strong>KEY DRUGS COVERED<\/strong><\/p>\n<p>Benlysta (IV), Benlysta (SC), Rituxan (rituximab), Orencia (abatacept), mycophenolate mofetil, cyclophosphamide, azathioprine, cyclosporine, methotrexate, tacrolimus, hydroxychloroquine.<\/p>\n<p><strong>KEY INSIGHTS PROVIDED<\/strong><\/p>\n<ul>\n<li>Factors influencing disease management and treatment decisions.<\/li>\n<li>Drivers and constraints of treatment selection.<\/li>\n<li>Physician reported treatment practices and brand-level patient shares.<\/li>\n<li>Rationale for changes in treatment approach.<\/li>\n<li>Physician insight on persistency and compliance.<\/li>\n<li>Physician reported recent\/anticipated changes in brand usage or treatment approach.<\/li>\n<\/ul>\n","protected":false},"template":"","class_list":["post-390593","report","type-report","status-publish","hentry","report-gateway-biopharma","biopharma-therapy-areas-systemic-lupus-erythematosus","biopharma-product-current-treatment","biopharma-geography-us","biopharma-date-920"],"acf":[],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/390593","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report"}],"about":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/types\/report"}],"version-history":[{"count":1,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/390593\/revisions"}],"predecessor-version":[{"id":393717,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/390593\/revisions\/393717"}],"wp:attachment":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/media?parent=390593"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}