{"id":390465,"date":"2019-03-08T00:00:00","date_gmt":"2019-03-08T00:00:00","guid":{"rendered":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/dlsfmd0009-2019-biopharma-type-1-diabetes-disease-landscape-and-forecast-g7-2019\/"},"modified":"2026-03-31T10:47:14","modified_gmt":"2026-03-31T10:47:14","slug":"dlsfmd0009-2019-biopharma-type-1-diabetes-disease-landscape-and-forecast-g7-2019","status":"publish","type":"report","link":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/dlsfmd0009-2019-biopharma-type-1-diabetes-disease-landscape-and-forecast-g7-2019\/","title":{"rendered":"Type 1 Diabetes | Disease Landscape and Forecast | G7 | 2019"},"content":{"rendered":"<p>Decision Resources Group anticipates the next ten years to be an exciting time in the type 1 diabetes (T1D) space\u00a0as the number of treatment options continues to grow. Existing agents fail to provide sustained and intrinsic control of\u00a0T1D, and none address the autoimmune component of\u00a0T1D\u2019s etiology. While late-stage pipeline therapies in development represent drug classes already on the market (e.g.,\u00a0SGLT-2\u00a0inhibitors), several early-stage pipeline therapies present genuine novel mechanisms of action. There is a shifting emphasis on the types of therapies in development for\u00a0T1D, with significant interest in pancreatic beta-cell replacement therapies and CD3 antigen inhibitors. The launch of biosimilar insulins\u00a0is having a profound effect on the\u00a0T1D\u00a0market across the G7, and we are witnessing an intricate interplay of physician and payer attitudes to this new treatment option.<\/p>\n<p><strong>Questions Answered<\/strong><\/p>\n<ul><\/p>\n<li><strong>What<\/strong><strong>\u00a0clinical role will oral therapies, regenerative\u00a0approaches, and immunological approaches\u00a0play in the evolving\u00a0T1D\u00a0treatment landscape?<\/strong><\/li>\n<p><\/p>\n<li><strong>What will be the market impact of Boehringer Ingelheim\/Eli Lilly\u2019s Abasaglar and other biosimilars? How resistant are physicians to payer pressure regarding switching patients to biosimilars?<\/strong><\/li>\n<p><\/p>\n<li><strong>How will endocrinologists differentiate between the emerging therapies, and which will enjoy the greatest clinical and commercial success in an increasingly stringent regulatory environment?<\/strong><\/li>\n<p><\/p>\n<li><strong>What can entrenched\u00a0T1D\u00a0players do to further protect their franchises from biosimilar and novel agent competition?<\/strong><\/li>\n<p>\t\u00a0\n<\/ul>\n<p><strong>Scope<\/strong><\/p>\n<p><strong>Markets covered:\u00a0<\/strong>United States, France, Germany, Italy, Spain, United Kingdom, and Japan.<\/p>\n<p><strong>Primary research:\u00a0<\/strong>20 country-specific interviews with thought-leaders and endocrinologists. Patient shares surveyed in all regions.<\/p>\n<p><strong>Epidemiology:\u00a0<\/strong>Diagnosed prevalence; 3 drug-treated subpopulations modeled\u2014 adult, adolescent, and child.<\/p>\n<p><strong>Emerging therapies:\u00a0<\/strong>Phase II: 30+\u00a0drugs; Phase III: 7\u00a0drugs; preregistration: 2\u00a0drugs. Coverage of select preclinical and Phase I products.<\/p>\n<p><strong>Market forecast features:<\/strong>\u00a0Using a proprietary model, we forecast population sizes and\u00a0T1D\u00a0drug sales for rolled-up adult, adolescent, and child patient segments through 2026.<\/p>\n<p><strong>Key companies:\u00a0<\/strong>Novo Nordisk, Sanofi, Eli Lilly,\u00a0Merck, Boehringer\u00a0Ingelheim, Samsung Bioepis, Mylan, Biocon, Astellas, Janssen, Bristol-Myers Squibb, AstraZeneca, Lexicon, Sanofi<\/p>\n<p><strong>Key drugs:\u00a0<\/strong>Lantus, Levemir, Toujeo, Tresiba, Abasaglar,\u00a0NovoLog, Humalog, Fiasp, Admelog, Ryzodeg,\u00a0Jardiance, Farxiga, Invokana, Suglat,\u00a0sotagliflozin.<\/p>\n","protected":false},"template":"","class_list":["post-390465","report","type-report","status-publish","hentry","report-gateway-biopharma","biopharma-therapy-areas-type-1-diabetes","biopharma-therapy-areas-type-2-diabetes","biopharma-date-931"],"acf":[],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/390465","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report"}],"about":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/types\/report"}],"version-history":[{"count":1,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/390465\/revisions"}],"predecessor-version":[{"id":393590,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/390465\/revisions\/393590"}],"wp:attachment":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/media?parent=390465"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}