{"id":389962,"date":"2021-11-10T00:00:00","date_gmt":"2021-11-10T00:00:00","guid":{"rendered":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/dlsfon0001-2021-biopharma-breast-cancer-disease-landscape-and-forecast-g7-2021\/"},"modified":"2026-04-22T05:21:17","modified_gmt":"2026-04-22T05:21:17","slug":"dlsfon0001-2021-biopharma-breast-cancer-disease-landscape-and-forecast-g7-2021","status":"publish","type":"report","link":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/dlsfon0001-2021-biopharma-breast-cancer-disease-landscape-and-forecast-g7-2021\/","title":{"rendered":"Breast Cancer | Disease Landscape and Forecast | G7 | 2021"},"content":{"rendered":"<p>Characterized by high incidence and long treatment durations, the breast cancer therapy market represents substantial commercial opportunity for drug developers. CDK4\/6 inhibitors (Pfizer\u2019s Ibrance, Novartis\u2019s Kisqali, and Eli Lilly\u2019s Verzenio\/Verzenios) are creating new dynamics in the treatment of metastatic HR-positive\/HER2-negative disease. Meanwhile, novel HER2-targeted agents, label expansions, and biosimilar entries\u2014all of which will lead to changes in treatment guidelines\u2014will have an impact on sales of current drugs for HER2-positive breast cancer. Furthermore, the approval of PARP inhibitors (AstraZeneca \/ Merck &#038; Co.\u2019s Lynparza and Pfizer\u2019s Talzenna), immune checkpoint inhibitors (Roche \/ Genentech \/ Chugai\u2019s Tecentriq and Merck &#038; Co.\u2019s Keytruda), PI3K inhibitors (Novartis\u2019s Piqray), HER2-targeted agents (Daiichi Sankyo \/ AstraZeneca\u2019s Enhertu, Seagen \/ Pfizer\u2019s Tukysa, and MacroGenics\u2019 Margenza), and TROP2-targeted agents (Gilead\u2019s Trodelvy), as well as the anticipated entry of other agents from these drug classes, will diversify treatment options, especially for triple-negative breast cancer.<\/p>\n<p><strong>QUESTIONS ANSWERED<\/strong><\/p>\n<ul>\n<li>What is the size of the drug-treatable breast cancer population, and how will drug-treatment rates change over time?<\/li>\n<li>What is the expected market impact of recent drug approvals, such as Keytruda, Piqray, Enhertu, and Tukysa, on the various subpopulations of breast cancer?<\/li>\n<li>What are the most promising agents in the pipeline, and how will they shape the future of the breast cancer therapy market?<\/li>\n<li>What are the drivers and constraints in the breast cancer market, and how will the market evolve over the forecast period?<\/li>\n<\/ul>\n<p><strong>PRODUCT DESCRIPTION<\/strong><\/p>\n<p><em>Disease Landscape &#038; Forecast<\/em> provides comprehensive market intelligence with world-class epidemiology, keen insight into current treatment paradigms, in-depth pipeline assessments, and drug forecasts supported by detailed primary and secondary research.<\/p>\n<p><strong>SOLUTION ENHANCEMENT<\/strong><\/p>\n<p><em>Disease Landscape &#038; Forecast<\/em> will feature continuous updates in 2021 to provide timely insights and analyses as meaningful indication-specific news and events unfold.<\/p>\n<p><strong>CONTENT HIGHLIGHTS<\/strong><\/p>\n<ul>\n<li>Geographies: United States, EU5, Japan.<\/li>\n<li>Primary research: 19 country-specific interviews with thought-leading medical oncologists supported by survey data collected for this and other Clarivate research.<\/li>\n<li>Epidemiology: Incidence of breast cancer by country, segmented by HR and HER2 status, staging, and line of therapy.<\/li>\n<li>Forecast: 10-year, annualized, drug-level sales and patient share of key breast cancer therapies through 2030, segmented by brands \/ biosimilars \/ generics and market-relevant drug-treatable populations.<\/li>\n<li>Emerging therapies: Phase III\/PR: 18 drugs; coverage of select Phase I and II products.<\/li>\n<\/ul>\n","protected":false},"template":"","class_list":["post-389962","report","type-report","status-publish","hentry","report-gateway-biopharma","biopharma-therapy-areas-breast-cancer","biopharma-date-950"],"acf":[],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/389962","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report"}],"about":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/types\/report"}],"version-history":[{"count":2,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/389962\/revisions"}],"predecessor-version":[{"id":576353,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/389962\/revisions\/576353"}],"wp:attachment":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/media?parent=389962"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}