{"id":389825,"date":"2022-05-23T00:00:00","date_gmt":"2022-05-23T00:00:00","guid":{"rendered":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/acreim0014-2022-biopharma-atopic-dermatitis-access-reimbursement-us-2022\/"},"modified":"2026-04-27T23:31:56","modified_gmt":"2026-04-27T23:31:56","slug":"acreim0014-2022-biopharma-atopic-dermatitis-access-reimbursement-us-2022","status":"publish","type":"report","link":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/acreim0014-2022-biopharma-atopic-dermatitis-access-reimbursement-us-2022\/","title":{"rendered":"Atopic Dermatitis | Access &#038; Reimbursement | US | 2022"},"content":{"rendered":"<p>The treatment landscape for atopic dermatitis (AD) in the United States is undergoing a revolution. Since 2017, six new agents have been approved by the FDA (four of them since the start of 2021), including two systemic JAK inhibitors, two nonsteroidal topical therapies, and two injectable biological drugs. Treatment of patients with mild and moderate AD relies on topical agents, traditionally corticosteroids, as the mainstay of treatment, while patients with moderate to severe AD may be treated with systemic immunosuppressants like azathioprine or cyclosporine. Newer topical agents like Pfizer\u2019s PDE-4 inhibitor Eucrisa (crisaborole) and Incyte\u2019s JAK inhibitor Opzelura (ruxolitinib) are expanding treatment options for mild to moderate AD, while newer options for the treatment of moderate to severe AD include injectable targeted biologics (Sanofi \/ Regeneron\u2019s Dupixent [dupilumab] and LEO\u2019s Adbry [tralokinumab]) and systemic JAK inhibitors (Pfizer\u2019s Cibinqo [abrocitinib] and AbbVie\u2019s Rinvoq [upadacitinib]). While Dupixent and Eucrisa, both approved in 2017, have established their niches in AD treatment, the views and policies of physicians and payers on more recently approved therapies, which we explore in depth in this report, will influence physician prescribing of and patient access to these newer therapies and ultimately shape both the AD treatment landscape and the AD drug market.<\/p>\n<p><strong>QUESTIONS ANSWERED<\/strong><\/p>\n<ul>\n<li>What are the current prescribing practices for AD, and how are they impacted by payer policy?<\/li>\n<li>What are physicians\u2019 and payers\u2019 initial reactions to Opzelura, Adbry, Cibinqo, and Rinvoq, and how has \/ will these agents\u2019 availability for AD impact physician prescribing and payer reimbursement?<\/li>\n<li>How will dermatologists\u2019 prescribing of established agents by line of therapy shift as these new agents are incorporated into the treatment algorithm?<\/li>\n<li>As systemic JAK inhibitors are granted label expansions for AD, to what extent will payers consider using an indication-based formulary approach?<\/li>\n<li>What are payer and physician perspectives on promising but likely costly emerging agents such as Dermira\u2019s lebrikizumab and Chugai \/ Dermira \/ Maruho\u2019s nemolizumab?<\/li>\n<\/ul>\n<p><strong>CONTENT HIGHLIGHTS <\/strong><\/p>\n<p><strong>Geography:<\/strong> United States<\/p>\n<p><strong>Primary Research:<\/strong> Survey of 102 U.S. dermatologists. Survey of 31 U.S. managed care organization (MCO) pharmacy and medical directors (PDs\/MDs).<\/p>\n<p><strong>Key Drugs Covered: <\/strong>Dupixent, Eucrisa, Cibinqo, Rinvoq, Olumiant, Adbry, Opzelura, lebrikizumab, nemolizumab,\u00a0topical corticosteroids, topical calcineurin inhibitors.<\/p>\n<p><strong>PRODUCT DESCRIPTION<\/strong><\/p>\n<p><em>U.S. Access &#038; Reimbursement<\/em> provides integrated brand- and disease-level insight on reimbursement dynamics and the impact of U.S. payer policy on physician prescribing behavior in the market access environment, including up-to-date analysis of drug coverage and restriction policies and payer and prescriber perspectives on key marketed drugs and receptivity to emerging therapies.<\/p>\n","protected":false},"template":"","class_list":["post-389825","report","type-report","status-publish","hentry","report-gateway-biopharma","biopharma-geography-us","biopharma-date-960"],"acf":[],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/389825","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report"}],"about":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/types\/report"}],"version-history":[{"count":2,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/389825\/revisions"}],"predecessor-version":[{"id":576246,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/389825\/revisions\/576246"}],"wp:attachment":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/media?parent=389825"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}