{"id":295580,"date":"2023-03-09T00:00:00","date_gmt":"2023-03-09T00:00:00","guid":{"rendered":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/cutrcg0011-2023-biopharma-migraine-current-treatment-current-treatment-physician-insights-migraine\/"},"modified":"2026-03-31T10:34:38","modified_gmt":"2026-03-31T10:34:38","slug":"cutrcg0011-2023-biopharma-migraine-current-treatment-current-treatment-physician-insights-migraine-prophylaxis-us","status":"publish","type":"report","link":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/cutrcg0011-2023-biopharma-migraine-current-treatment-current-treatment-physician-insights-migraine-prophylaxis-us\/","title":{"rendered":"Migraine &#8211; Current Treatment &#8211; Current Treatment: Physician Insights &#8211; Migraine Prophylaxis (US)"},"content":{"rendered":"<p>Prophylactic therapy for migraine is prescribed to reduce migraine frequency, severity, and duration of attacks and to increase responsiveness of attacks to acute treatment. Generic oral <abbr data-abbreviation-entity=\"4723\" title=\"antiepileptic drug\">AED<\/abbr>s (e.g., topiramate), beta blockers (e.g., propranolol), antidepressants (e.g., amitriptyline), and AbbVie\u2019s Botox are historical mainstays, but an influx of novel <abbr data-abbreviation-entity=\"4758\" title=\"calcitonin gene-related peptide\">CGRP<\/abbr>-targeting injectable (Amgen\/Novartis\u2019s Aimovig, Teva\u2019s Ajovy, Eli Lilly\u2019s Emgality, and Lundbeck\u2019s Vyepti) and oral (Pfizer\u2019s Nurtec <abbr data-abbreviation-entity=\"5333\" title=\"orally disintegrating tablet\">ODT<\/abbr> and AbbVie\u2019s Qulipta) prophylactic agents is transforming the paradigm. Although they target a common pathway, these novel agents differ meaningfully in their clinical profile, in addition to their route and frequency of administration; as such, they appeal differentially to patients and the various specialists prescribing prophylactic treatment (e.g., <abbr data-abbreviation-entity=\"4927\" title=\"primary care physician\">PCP<\/abbr>s, neurologists). Understanding prescribing patterns and drivers is paramount for established agents competing for market share and for developers of emerging treatments.<\/p>\n<p><strong>QUESTIONS ANSWERED<\/strong><\/p>\n<ul class=\"round-bullets\">\n<li>How do <abbr data-abbreviation-entity=\"4927\" title=\"primary care physician\">PCP<\/abbr>s and neurologists differ in their prescribing for migraine prophylaxis?<\/li>\n<li>What patient share do key prophylactic therapies and brands attain in chronic and episodic migraine patients and by line of therapy in migraine patients initiating prophylaxis?<\/li>\n<li>What impact has the entry of the oral <abbr data-abbreviation-entity=\"4758\" title=\"calcitonin gene-related peptide\">CGRP<\/abbr>-targeted therapies had on the prescribing of anti-<abbr data-abbreviation-entity=\"4758\" title=\"calcitonin gene-related peptide\">CGRP<\/abbr> <abbr data-abbreviation-entity=\"4880\" title=\"monoclonal antibody\">MAb<\/abbr>s, and what drives this dynamic?<\/li>\n<li>Which anti-<abbr data-abbreviation-entity=\"4758\" title=\"calcitonin gene-related peptide\">CGRP<\/abbr> <abbr title=\"monoclonal antibody\">MAb<\/abbr>s perform best on key clinical factors? Which are most prescribed, and why?<\/li>\n<li>What impact has the emergence of anti-<abbr data-abbreviation-entity=\"4758\" title=\"calcitonin gene-related peptide\">CGRP<\/abbr> <abbr data-abbreviation-entity=\"4880\" title=\"monoclonal antibody\">MAb<\/abbr>s had on the prescribing of Botox, and what drives this dynamic?<\/li>\n<li>What percentage of patients are treated with monotherapy versus combination therapy? What are the most common combinations?<\/li>\n<li>What are physicians\u2019 goals regarding the duration of prophylactic therapy, and at what point do they re-evaluate whether to continue it?<\/li>\n<\/ul>\n<p><strong>PRODUCT DESCRIPTION<\/strong><\/p>\n<p>Current Treatment: Physician Insights provides physician insights on treatment dynamics, prescribing behavior, and drivers of brand use so that marketers can create specific messaging around these treatment dynamics to more effectively increase or defend their market position.<\/p>\n","protected":false},"template":"","class_list":["post-295580","report","type-report","status-publish","hentry","report-gateway-biopharma","biopharma-therapy-areas-migraine","biopharma-product-current-treatment","biopharma-geography-us","biopharma-date-975"],"acf":[],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/295580","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report"}],"about":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/types\/report"}],"version-history":[{"count":1,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/295580\/revisions"}],"predecessor-version":[{"id":295810,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/295580\/revisions\/295810"}],"wp:attachment":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/media?parent=295580"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}