{"id":295567,"date":"2023-05-25T00:00:00","date_gmt":"2023-05-25T00:00:00","guid":{"rendered":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/cutrcg0018-2023-biopharma-migraine-current-treatment-current-treatment-physician-insights-migraine\/"},"modified":"2026-04-15T09:41:41","modified_gmt":"2026-04-15T09:41:41","slug":"cutrcg0018-2023-biopharma-migraine-current-treatment-current-treatment-physician-insights-migraine-prophylaxis-eu5","status":"publish","type":"report","link":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/cutrcg0018-2023-biopharma-migraine-current-treatment-current-treatment-physician-insights-migraine-prophylaxis-eu5\/","title":{"rendered":"Migraine &#8211; Current Treatment &#8211; Current Treatment: Physician Insights &#8211; Migraine Prophylaxis (EU5)"},"content":{"rendered":"<p>Prophylactic therapy for migraine is prescribed to reduce the frequency, severity, and duration of migraine attacks and to increase the responsiveness of these attacks to acute treatment. Generic oral <abbr title=\"antiepileptic drug\">AED<\/abbr>s (e.g., topiramate), beta blockers (e.g., propranolol), antidepressants (e.g., amitriptyline), and AbbVie\u2019s Botox are historical mainstays, but an influx of novel <abbr title=\"calcitonin gene-related peptide\">CGRP<\/abbr>-targeting injectables (Amgen\/Novartis\u2019s Aimovig, Teva\u2019s Ajovy, Eli Lilly\u2019s Emgality, and, more recently in select European markets, Lundbeck\u2019s Vyepti) is transforming the paradigm, with further changes expected following the anticipated entry of oral prophylactic agents in Europe, including Pfizer\u2019s Vydura (Nurtec <abbr title=\"orally disintegrating tablet\">ODT<\/abbr>) and AbbVie\u2019s Qulipta. Although they target a common pathway, these novel agents differ meaningfully in their clinical profile, in addition to their route and frequency of administration; as such, they appeal differentially to patients and the various specialists prescribing prophylactic treatment (e.g., general practitioners \/ internal medicine physicians [<abbr title=\"general practitioner\">GP<\/abbr>s \/ <abbr title=\"internal medicine physician\">IM<\/abbr>s], neurologists). Understanding prescribing patterns and drivers is paramount for established agents competing for market share and for developers of emerging treatments.<\/p>\n<p><strong>QUESTIONS ANSWERED<\/strong><\/p>\n<ul class=\"round-bullets\">\n<li>How do <abbr title=\"general practitioner\">GP<\/abbr>\/<abbr title=\"internal medicine physician\">IM<\/abbr>s and neurologists differ in their prescribing for migraine prophylaxis?<\/li>\n<li>What patient share do key prophylactic therapies and brands attain in chronic and episodic migraine patients and by line of therapy in migraine patients initiating prophylaxis?<\/li>\n<li>What impact will the entry of the oral <abbr title=\"calcitonin gene-related peptide\">CGRP<\/abbr>-targeted therapies have on the prescribing of anti-<abbr title=\"calcitonin gene-related peptide\">CGRP<\/abbr> <abbr title=\"monoclonal antibody\">MAb<\/abbr>s, and what factors will drive this dynamic?<\/li>\n<li>Which anti-<abbr title=\"calcitonin gene-related peptide\">CGRP<\/abbr> <abbr title=\"monoclonal antibody\">MAb<\/abbr>s perform best on key clinical factors? Which are most prescribed, and why?<\/li>\n<li>What impact has the emergence of anti-<abbr title=\"calcitonin gene-related peptide\">CGRP<\/abbr> <abbr title=\"monoclonal antibody\">MAb<\/abbr>s had on the prescribing of Botox, and what drives this dynamic?<\/li>\n<li>What percentage of patients are treated with monotherapy versus combination therapy? What are the most common combinations?<\/li>\n<li>What are physicians\u2019 goals regarding the duration of prophylactic therapy, and at what point do they reevaluate whether to continue treatment?<\/li>\n<\/ul>\n<p><strong>PRODUCT DESCRIPTION<\/strong><\/p>\n<p><em>Current Treatment: Physician Insights<\/em> provides physician insights on treatment dynamics, prescribing behavior, and drivers of brand use so that marketers can create specific messaging around these treatment dynamics to more effectively increase or defend their market position.<\/p>\n","protected":false},"template":"","class_list":["post-295567","report","type-report","status-publish","hentry","report-gateway-biopharma","biopharma-therapy-areas-migraine","biopharma-product-current-treatment","biopharma-date-975"],"acf":[],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/295567","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report"}],"about":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/types\/report"}],"version-history":[{"count":1,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/295567\/revisions"}],"predecessor-version":[{"id":295797,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/295567\/revisions\/295797"}],"wp:attachment":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/media?parent=295567"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}