{"id":251795,"date":"2021-02-22T00:00:00","date_gmt":"2021-02-22T00:00:00","guid":{"rendered":"https:\/\/clarivate.com\/products\/research-reports\/report\/epidor0002-biopharma-tuberous-sclerosis-epidemiology-mature-markets\/"},"modified":"2026-03-31T10:43:54","modified_gmt":"2026-03-31T10:43:54","slug":"epidor0002-biopharma-tuberous-sclerosis-epidemiology-mature-markets","status":"publish","type":"report","link":"https:\/\/clarivate.com\/life-sciences-healthcare\/report\/epidor0002-biopharma-tuberous-sclerosis-epidemiology-mature-markets\/","title":{"rendered":"Tuberous Sclerosis &#8211; Epidemiology &#8211; Mature Markets"},"content":{"rendered":"<p><abbr title=\"Decision Resources Group\">DRG<\/abbr> Epidemiology\u2019s coverage of tuberous sclerosis comprises epidemiological estimates of key patient populations in\u00a0the major mature pharmaceutical markets (the United States, France, Germany, Italy, Spain, the United Kingdom, and Japan). We report the prevalence of tuberous sclerosis for each country, as well as annualized case counts projected to the national population.<\/p>\n<p>Most patient populations are forecast over a period of 20 years for the major mature pharmaceutical markets covered in this report.<\/p>\n<p><abbr title=\"Decision Resources Group\">DRG<\/abbr> Epidemiology\u2019s tuberous sclerosis forecast will answer the following questions:<\/p>\n<ul class=\"round-bullets\">\n<li>How will demographic trends, such as population aging and improving life expectancy, affect the epidemiology of tuberous sclerosis over the forecast period?<\/li>\n<\/ul>\n<p>All forecast data are available on the <abbr title=\"Decision Resources Group\">DRG<\/abbr> Insights Platform in tabular format, with options to download to MS Excel. All populations are accompanied by a comprehensive description of the methods and data sources used, with hyperlinks to external sources. A summary evidence table generated as part of our systematic review of the epidemiological literature is also provided for full transparency into research and methods.<\/p>\n<p>In total, <abbr title=\"Decision Resources Group\">DRG<\/abbr> Epidemiology forecasts six\u00a0tuberous sclerosis patient populations, as follows:<\/p>\n<ul class=\"round-bullets\">\n<li>Diagnosed prevalent cases.<\/li>\n<li>Diagnosed prevalent cases with the\u00a0<abbr title=\"tuberous sclerosis complex subunit 1 \">TSC1<\/abbr> genotype.<\/li>\n<li>Diagnosed prevalent cases with the\u00a0<abbr title=\"tuberous sclerosis complex subunit 2 \">TSC2<\/abbr> genotype.<\/li>\n<li>Diagnosed prevalent cases with no mutation identified.<\/li>\n<li>Diagnosed prevalent cases with epilepsy.<\/li>\n<li>Diagnosed prevalent cases with developmental delays.<\/li>\n<li>\u2026 and more (details available on request).<\/li>\n<\/ul>\n<p>Note: Coverage may vary by country.<\/p>\n","protected":false},"template":"","class_list":["post-251795","report","type-report","status-publish","hentry","report-gateway-biopharma","biopharma-product-epidemiology","biopharma-geography-us","biopharma-date-950"],"acf":[],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/251795","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report"}],"about":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/types\/report"}],"version-history":[{"count":1,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/251795\/revisions"}],"predecessor-version":[{"id":284249,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/report\/251795\/revisions\/284249"}],"wp:attachment":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/media?parent=251795"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}