{"id":577640,"date":"2026-03-26T07:23:35","date_gmt":"2026-03-26T07:23:35","guid":{"rendered":"https:\/\/clarivate.com\/life-sciences-healthcare\/?p=574608"},"modified":"2026-06-30T08:25:15","modified_gmt":"2026-06-30T08:25:15","slug":"drugs-to-watch-2026-qa-lillys-next-generation-weight-loss-drugs","status":"publish","type":"post","link":"https:\/\/clarivate.com\/life-sciences-healthcare\/ja\/blog\/drugs-to-watch-2026-qa-lillys-next-generation-weight-loss-drugs\/","title":{"rendered":"Drugs to Watch 2026 Q&A\uff1aEli Lily\u793e\u306e\u6b21\u4e16\u4ee3\u6e1b\u91cf\u85ac"},"content":{"rendered":"

\u6700\u8fd1\u958b\u50ac\u3057\u305f\u30a6\u30a7\u30d3\u30ca\u30fcDrugs to Watch 2026: Navigating the next wave of GLP-1 evolution and beyond<\/a> \u306b\u306f\u3001\u53c2\u52a0\u8005\u304b\u3089\u975e\u5e38\u306b\u512a\u308c\u305f\u8cea\u554f\u304c\u5bc4\u305b\u3089\u308c\u307e\u3057\u305f\u3002Clarivate\u306e\u30a2\u30ca\u30ea\u30b9\u30c8\u3067\u3042\u308bCarles Recasens\u3068Shambhavi Shukla\u304c\u3001\u3053\u3053\u3067\u305d\u306e\u56de\u7b54\u3092\u304a\u5c4a\u3051\u3057\u307e\u3059\u3002<\/p>\n

Retatrutide:<\/strong><\/h3>\n

\u73fe\u5728\u5229\u7528\u53ef\u80fd\u306a\u85ac\u5264\u3068\u306e\u6709\u52b9\u6027\u6bd4\u8f03 <\/strong><\/h3>\n

Q\uff1aRetatrutide\u306b\u3088\u308b\u4f53\u91cd\u6e1b\u5c11\u306f\u3001\u7dcf\u4f53\u91cd\u6e1b\u5c11\u306b\u5360\u3081\u308b\u9664\u8102\u80aa\u4f53\u91cd\u306e\u6e1b\u5c11\u5272\u5408\u3068\u3044\u3046\u89b3\u70b9\u3067\u3001\u73fe\u5728\u5229\u7528\u53ef\u80fd\u306a\u85ac\u5264\u3068\u6bd4\u3079\u3066\u3069\u3046\u3067\u3057\u3087\u3046\u304b\u3002<\/p>\n

A\uff1aRetatrutide\u306f\u3001\u73fe\u5728\u306eGLP-1\u85ac\u3068\u6bd4\u8f03\u3057\u3066\u3001\u7dcf\u4f53\u91cd\u6e1b\u5c11\u306b\u5bfe\u3059\u308b\u9664\u8102\u80aa\u4f53\u91cd\u6e1b\u5c11\u306e\u5272\u5408\u306f\u304a\u304a\u3080\u306d\u540c\u7a0b\u5ea6\u3067\u3042\u308b\u3068\u307f\u3089\u308c\u307e\u3059\u30022\u578b\u7cd6\u5c3f\u75c5\u3068\u80a5\u6e80\u3092\u6709\u3059\u308b\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u4f53\u7d44\u6210\u30b5\u30d6\u89e3\u6790(PMID: 40609566<\/a>)\u3067\u306f\u3001Retatrutide\u306b\u3088\u308b\u9664\u8102\u80aa\u4f53\u91cd\u6e1b\u5c11\u306f\u7dcf\u4f53\u91cd\u6e1b\u5c11\u306e\u7d0438%\u3067\u3042\u308a\u3001semaglutide\u3084tirzepatide\u306a\u3069\u4ed6\u306eGLP-1\u30d9\u30fc\u30b9\u6cbb\u7642\u3067\u5831\u544a\u3055\u308c\u3066\u3044\u308b20\uff5e40%\u306e\u7bc4\u56f2\u5185\u306b\u53ce\u307e\u3063\u3066\u3044\u307e\u3059(PMID: 40609564<\/a>; 39344838<\/a>). \u3053\u308c\u3089\u306e\u6240\u898b\u306f\u3001Retatrutide\u306e\u3088\u308a\u9ad8\u3044\u6e1b\u91cf\u52b9\u679c\u304c\u3001\u9664\u8102\u80aa\u4f53\u91cd\u5272\u5408\u306e\u3088\u308a\u5927\u304d\u306a\u640d\u5931\u3092\u4ee3\u511f\u3068\u3057\u3066\u3044\u308b\u308f\u3051\u3067\u306f\u306a\u3044\u3053\u3068\u3092\u793a\u5506\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u81e8\u5e8a\u7684\u306a\u89b3\u70b9\u304b\u3089\u898b\u308b\u3068\u3001Retatrutide\u306b\u95a2\u3059\u308b\u4e3b\u306a\u691c\u8a0e\u4e8b\u9805\u3001\u305d\u3057\u3066\u6f5c\u5728\u7684\u306a\u61f8\u5ff5\u306f\u3001\u5931\u308f\u308c\u308b\u9664\u8102\u80aa\u4f53\u91cd\u306e\u5272\u5408\u305d\u306e\u3082\u306e\u3067\u306f\u306a\u304f\u3001\u305d\u306e\u7d76\u5bfe\u91cf\u306b\u3042\u308a\u307e\u3059\u3002Retatrutide\u306b\u3088\u308b\u7dcf\u4f53\u91cd\u6e1b\u5c11\u306f\u4ed6\u306eGLP-1\u6cbb\u7642\u3088\u308a\u5927\u304d\u3044\u305f\u3081\u3001\u9664\u8102\u80aa\u4f53\u91cd\u306e\u7d76\u5bfe\u7684\u306a\u6e1b\u5c11\u91cf\u3082\u3088\u308a\u5927\u304d\u304f\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u3001\u3053\u308c\u306f\u9ad8\u9f62\u8005\u3001\u865a\u5f31\u60a3\u8005\u3001\u305d\u306e\u4ed6\u306e\u30cf\u30a4\u30ea\u30b9\u30af\u60a3\u8005\u96c6\u56e3\u306b\u304a\u3044\u3066\u91cd\u8981\u306a\u5f71\u97ff\u3092\u6301\u3064\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u7b4b\u91cf\u306e\u7dad\u6301<\/strong><\/h3>\n

Q:GLP-1\u6642\u4ee3\u306b\u304a\u3044\u3066\u3001\u7b4b\u91cf\u7dad\u6301\u3078\u306e\u61f8\u5ff5\u304c\u9ad8\u307e\u3063\u3066\u3044\u307e\u3059\u3002\u4f01\u696d\u306f\u3053\u308c\u306b\u3069\u306e\u3088\u3046\u306b\u9069\u5fdc\u3057\u3066\u3044\u304f\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u304b\u3002\u7b4b\u4fdd\u8b77\u3084\u6a5f\u80fd\u6539\u5584\u306f\u3001\u305d\u308c\u81ea\u4f53\u304c\u72ec\u7acb\u3057\u305f\u5275\u85ac\u30ab\u30c6\u30b4\u30ea\u30fc\u306b\u306a\u308b\u306e\u3067\u3057\u3087\u3046\u304b\u3002\u305d\u308c\u3068\u3082\u3001\u4e3b\u3068\u3057\u3066\u30a4\u30f3\u30af\u30ec\u30c1\u30f3\u6cbb\u7642\u3078\u306e\u8ffd\u52a0\u8981\u7d20\u306b\u3068\u3069\u307e\u308b\u306e\u3067\u3057\u3087\u3046\u304b\u3002<\/p>\n

A\uff1a\u7b4b\u4fdd\u8b77\u3078\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u306f\u30011\u3064\u306e\u91cd\u8981\u306a\u8981\u56e0\u306b\u5de6\u53f3\u3055\u308c\u307e\u3059\u3002\u3059\u306a\u308f\u3061\u3001GLP-1\u6cbb\u7642\u3067\u89b3\u5bdf\u3055\u308c\u308b\u7b4b\u8089\u6e1b\u5c11\u304c\u3001\u3042\u3089\u3086\u308b\u30ab\u30ed\u30ea\u30fc\u4e0d\u8db3\u306b\u4f34\u3046\u60f3\u5b9a\u5185\u306e\u751f\u7406\u7684\u9069\u5fdc\u306a\u306e\u304b\u3001\u305d\u308c\u3068\u3082\u4e00\u90e8\u306e\u75c7\u4f8b\u3067\u306f\u81e8\u5e8a\u7684\u306b\u91cd\u8981\u3067\u3001\u6f5c\u5728\u7684\u306b\u75c5\u7684\u306a\u3082\u306e\u306a\u306e\u304b\u3092\u898b\u6975\u3081\u308b\u3053\u3068\u3067\u3059\u3002\u7279\u5b9a\u306e\u72b6\u6cc1\u3067\u75c5\u7684\u3067\u3042\u308b\u306a\u3089\u3001\u305d\u306e\u6839\u672c\u539f\u56e0\u3084\u30cf\u30a4\u30ea\u30b9\u30af\u60a3\u8005\u7fa4\u3092\u7279\u5b9a\u3059\u308b\u3053\u3068\u304c\u4e0d\u53ef\u6b20\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n

\u3053\u3046\u3057\u305f\u30cf\u30a4\u30ea\u30b9\u30af\u7fa4\u304c\u660e\u78ba\u306b\u5b9a\u7fa9\u3055\u308c\u308c\u3070\u3001\u305f\u3068\u3048\u3070\u53ef\u52d5\u6027\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u4eba\u3084\u30b5\u30eb\u30b3\u30da\u30cb\u30a2\u80a5\u6e80\u306e\u4eba\u306a\u3069\u306b\u5bfe\u3057\u3066\u3001\u81e8\u5e8a\u7ba1\u7406\u306f\u307e\u305a\u30ec\u30b8\u30b9\u30bf\u30f3\u30b9\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3084\u5341\u5206\u306a\u305f\u3093\u3071\u304f\u8cea\u6442\u53d6\u3068\u3044\u3063\u305f\u751f\u6d3b\u7fd2\u6163\u4ecb\u5165\u306e\u6700\u9069\u5316\u306b\u6ce8\u529b\u3057\u3001\u305d\u306e\u3046\u3048\u3067\u7b4b\u91cf\u6e29\u5b58\u85ac\u306e\u3088\u3046\u306a\u65b0\u305f\u306a\u85ac\u7406\u5b66\u7684\u4ecb\u5165\u3092\u8ffd\u52a0\u3059\u308b\u6d41\u308c\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u3067\u3057\u3087\u3046\u3002<\/p>\n

\u3053\u306e\u67a0\u7d44\u307f\u306b\u304a\u3044\u3066\u3001\u7b4b\u91cf\u6e29\u5b58\u85ac\u306f\u5f53\u521d\u3001\u5358\u72ec\u85ac\u3067\u306f\u306a\u304f\u3001GLP-1\u307e\u305f\u306f\u30a2\u30df\u30ea\u30f3\u30d9\u30fc\u30b9\u6cbb\u7642\u3078\u306e\u8ffd\u52a0\u85ac\u3068\u3057\u3066\u3001\u9ad8\u30ea\u30b9\u30af\u60a3\u8005\u306e\u8ee2\u5e30\u6539\u5584\u3092\u76ee\u7684\u306b\u7528\u3044\u3089\u308c\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u4eca\u5f8c\u6570\u5e74\u3067\u3001\u3053\u308c\u3089\u60a3\u8005\u7fa4\u306e\u5b9a\u7fa9\u3068\u5c64\u5225\u5316\u3001\u306a\u3089\u3073\u306bGLP-1\u6cbb\u7642\u60a3\u8005\u306b\u304a\u3051\u308b\u75c5\u7684\u306a\u7b4b\u8089\u6e1b\u5c11\u3084\u6a5f\u80fd\u4f4e\u4e0b\u306e\u660e\u78ba\u306a\u95be\u5024\u304c\u3001\u3088\u308a\u306f\u3063\u304d\u308a\u3057\u3066\u304f\u308b\u3068\u4e88\u60f3\u3055\u308c\u307e\u3059\u3002\u4e26\u884c\u3057\u3066\u3001\u865a\u5f31\u3067\u8106\u5f31\u306a\u30b3\u30db\u30fc\u30c8\u3092\u5bfe\u8c61\u306b\u3001\u7b4b\u8cea\u3001\u7b4b\u529b\u3001\u6a5f\u80fd\u7684\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u8a55\u4fa1\u9805\u76ee\u306b\u542b\u3080\u8a66\u9a13\u3092\u5b9f\u65bd\u3059\u308b\u958b\u767a\u4f01\u696d\u306f\u3001\u80a5\u6e80\u6cbb\u7642\u8a2d\u8a08\u306b\u304a\u3051\u308b\u91cd\u8981\u306a\u5dee\u5225\u5316\u8981\u56e0\u3068\u3057\u3066\u7b4b\u4fdd\u8b77\u3092\u4f4d\u7f6e\u3065\u3051\u308b\u3046\u3048\u3067\u4fa1\u5024\u3092\u6301\u3064\u3067\u3057\u3087\u3046\u3002<\/p>\n

\u30c8\u30ea\u30d7\u30eb\u30a2\u30b4\u30cb\u30b9\u30c8\u306e\u5e02\u5834\u30dd\u30c6\u30f3\u30b7\u30e3\u30eb<\/strong><\/h3>\n

Q:Retatrutide\u306f\u4e0a\u5e02\u6642\u70b9\u3067\u6700\u5927\u306e\u4f53\u91cd\u6e1b\u5c11\u3092\u8a34\u6c42\u3067\u304d\u305d\u3046\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u73fe\u5b9f\u7684\u306b\u5e02\u5834\u306e\u3069\u306e\u7a0b\u5ea6\u304c\u30c8\u30ea\u30d7\u30eb\u30a2\u30b4\u30cb\u30b9\u30c8\u3067\u6cbb\u7642\u3055\u308c\u308b\u3068\u304a\u8003\u3048\u3067\u3059\u304b\u3002\u91cd\u5ea6\u80a5\u6e80\u60a3\u8005\u306b\u9650\u3089\u308c\u308b\u306e\u3067\u3057\u3087\u3046\u304b\u3002\u307e\u305f\u3001\u3088\u308a\u30b7\u30f3\u30d7\u30eb\u306a\u80a5\u6e80\u6cbb\u7642\u85ac\u306e\u4f9b\u7d66\u62e1\u5927\u3001\u9078\u629e\u80a2\u5897\u52a0\u3001\u30a2\u30af\u30bb\u30b9\u6539\u5584\u304c\u9032\u3081\u3070\u3001\u3053\u306e\u30bb\u30b0\u30e1\u30f3\u30c8\u306f\u5927\u304d\u304f\u7e2e\u5c0f\u3059\u308b\u306e\u3067\u3057\u3087\u3046\u304b\u3002<\/p>\n

A\uff1aRetatrutide\u306f\u4e3b\u3068\u3057\u3066\u3001\u73fe\u5728\u306eGLP-1\u30d9\u30fc\u30b9\u6cbb\u7642\u3067\u306f\u5341\u5206\u306a\u4f53\u91cd\u6e1b\u5c11\u304c\u5f97\u3089\u308c\u306a\u3044\u60a3\u8005\u3001\u7279\u306b\u5fc3\u4ee3\u8b1d\u30ea\u30b9\u30af\u306e\u9ad8\u3044\u60a3\u8005\u306b\u7528\u3044\u3089\u308c\u308b\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n

tirzepatide\u3067\u3042\u3063\u3066\u3082\u3001\u4f9d\u7136\u3068\u3057\u3066\u30cb\u30fc\u30ba\u304c\u5341\u5206\u306b\u6e80\u305f\u3055\u308c\u3066\u3044\u306a\u3044\u60a3\u8005\u7fa4\u304c\u76f8\u5f53\u6570\u5b58\u5728\u3057\u307e\u3059\u3002\u3053\u308c\u306b\u306f\u3001BMI\u30b9\u30da\u30af\u30c8\u30e9\u30e0\u306e\u9ad8\u4f4d\u306b\u4f4d\u7f6e\u3059\u308b\u30af\u30e9\u30b92\u307e\u305f\u306f\u30af\u30e9\u30b93\u80a5\u6e80\u306e\u60a3\u8005\u3084\u3001\u6e1b\u91cf\u306b\u5bfe\u3057\u3066\u4ee3\u8b1d\u7684\u306b\u62b5\u6297\u6027\u304c\u9ad8\u3044\u50be\u5411\u306e\u3042\u308b2\u578b\u7cd6\u5c3f\u75c5\u5408\u4f75\u80a5\u6e80\u60a3\u8005\u304c\u542b\u307e\u308c\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u6cbb\u7642\u3092\u6bb5\u968e\u7684\u306b\u5f37\u5316\u3059\u308b\u30a2\u30d7\u30ed\u30fc\u30c1\u306b\u660e\u78ba\u306a\u6a5f\u4f1a\u3092\u751f\u307f\u51fa\u3057\u307e\u3059\u3002\u9069\u5207\u306a\u60a3\u8005\u7fa4\u306b\u304a\u3044\u3066Retatrutide\u304ctirzepatide\u306b\u5bfe\u3059\u308b\u660e\u78ba\u306a\u512a\u8d8a\u6027\u3092\u793a\u305b\u3070\u3001\u4f53\u91cd\u307e\u305f\u306f\u4ee3\u8b1d\u76ee\u6a19\u3092\u9054\u6210\u3067\u304d\u306a\u3044\u60a3\u8005\u306b\u3068\u3063\u3066\u81ea\u7136\u306a\u5f37\u5316\u9078\u629e\u80a2\u3068\u306a\u308a\u5f97\u307e\u3059\u3002<\/p>\n

\u91cd\u5ea6\u80a5\u6e80\u30bb\u30b0\u30e1\u30f3\u30c8\u304c\u6642\u9593\u3068\u3068\u3082\u306b\u6709\u610f\u306b\u7e2e\u5c0f\u3059\u308b\u53ef\u80fd\u6027\u306f\u4f4e\u3044\u3067\u3057\u3087\u3046\u3002\u5bfe\u8c61\u4eba\u53e3\u306f\u4f9d\u7136\u3068\u3057\u3066\u5927\u304d\u304f\u3001\u4f4e\u3044\u6709\u52b9\u6027\u306e\u6cbb\u7642\u3067\u306f\u3001\u3088\u308a\u5927\u304d\u306a\u4f53\u91cd\u6e1b\u5c11\u30cb\u30fc\u30ba\u3092\u6e80\u305f\u3059\u306b\u306f\u4e0d\u5341\u5206\u3067\u3059\u3002\u305f\u3068\u3048\u3070\u7c73\u56fd\u3067\u306f\u3001\u80a5\u6e80\u60a3\u8005\u306e\u304a\u3088\u305d50%\u304c\u30af\u30e9\u30b92\u307e\u305f\u306f\u30af\u30e9\u30b93\u80a5\u6e80\u3067\u3059\u3002\u3053\u3046\u3057\u305f\u60a3\u8005\u304c\u6b63\u5e38BMI\u3092\u9054\u6210\u3059\u308b\u306b\u306f\u3001\u7d0430\uff5e45%\u306e\u4f53\u91cd\u6e1b\u5c11\u304c\u5fc5\u8981\u306b\u306a\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002\u7b2c3\u76f8TRIUMPH-4\u8a66\u9a13\u306e\u30ab\u30c6\u30b4\u30ea\u30fc\u5225\u4f53\u91cd\u6e1b\u5c11\u30c7\u30fc\u30bf\u306b\u57fa\u3065\u304f\u3068\u3001\u3088\u308a\u91cd\u75c7\u306e\u96c6\u56e3\u3067\u306fRetatrutide\u3067\u3055\u3048\u3053\u306e\u30a2\u30f3\u30e1\u30c3\u30c8\u30cb\u30fc\u30ba\u3092\u5b8c\u5168\u306b\u306f\u6e80\u305f\u305b\u306a\u3044\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u3088\u308a\u30b7\u30f3\u30d7\u30eb\u3067\u30a2\u30af\u30bb\u30b9\u3057\u3084\u3059\u3044\u80a5\u6e80\u6cbb\u7642\u85ac\u304c\u5e83\u304f\u5229\u7528\u53ef\u80fd\u306b\u306a\u3063\u3066\u3082\u3001\u9ad8\u3044\u6709\u52b9\u6027\u3092\u6301\u3064\u6cbb\u7642\u304c\u5f15\u304d\u7d9a\u304d\u91cd\u8981\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

Orforglipron:<\/strong><\/h3>\n

\u6ce8\u5c04\u6050\u6016\u75c7<\/strong><\/h3>\n

Q\uff1aorforglipron\u304c\u5229\u7528\u53ef\u80fd\u306b\u306a\u308c\u3070\u3001\u6ce8\u5c04\u306b\u62b5\u6297\u306e\u3042\u308b\u60a3\u8005\u3067\u4f7f\u7528\u304c\u5897\u3048\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u304b\u3002<\/p>\n

A\uff1a\u306f\u3044\u3002\u6ce8\u5c04\u306b\u62b5\u6297\u306e\u3042\u308b\u60a3\u8005\u306b\u304a\u3044\u3066\u3001orforglipron\u306e\u4f7f\u7528\u306f\u5897\u52a0\u3059\u308b\u3068\u4e88\u60f3\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u305f\u3060\u3057\u3001orforglipron\u306e\u4f7f\u7528\u306f\u7d4c\u53e3\u5264\u3067\u3042\u308b\u3053\u3068\u3060\u3051\u3067\u6c7a\u307e\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u7d4c\u53e3semaglutide\uff08Rybelsus\uff09\u306f\u3059\u3067\u306b\u6570\u5e74\u524d\u304b\u3089\u5e02\u5834\u306b\u3042\u308a\u307e\u3059\u304c\u30012\u578b\u7cd6\u5c3f\u75c5\u306b\u304a\u3051\u308b\u4f7f\u7528\u306f\u4f9d\u7136\u3068\u3057\u3066\u9650\u5b9a\u7684\u3067\u3042\u308a\u3001\u60a3\u8005\u30b7\u30a7\u30a2\u304c\u6ce8\u5c04\u88fd\u5264\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u304b\u3089\u7d4c\u53e3semaglutide\u3078\u5927\u304d\u304f\u79fb\u3063\u305f\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3053\u306e\u9650\u5b9a\u7684\u306a\u63a1\u7528\u306f\u3001\u4e3b\u3068\u3057\u3066\u7d4c\u53e3semaglutide\u306b\u4f34\u3046\u53b3\u683c\u306a\u670d\u7528\u6761\u4ef6\u306b\u3088\u308b\u3082\u306e\u3067\u3059\u3002\u3053\u3046\u3057\u305f\u5236\u7d04\u306b\u52a0\u3048\u3066\u3001\u76f4\u63a5\u6bd4\u8f03\u8a66\u9a13ACHIEVE-3\u3067\u793a\u3055\u308c\u305f\u826f\u597d\u306a\u7d50\u679c\u3053\u305d\u304c\u3001orforglipron\u304c\u7d4c\u53e3semaglutide\u306b\u5bfe\u3057\u3066\u660e\u78ba\u306a\u512a\u4f4d\u6027\u3092\u6301\u3064\u70b9\u3067\u3059\u3002\u80a5\u6e80\u5e02\u5834\u3067\u306f\u3001\u7d4c\u53e3semaglutide\uff08Wegovy pill\uff09\u306e\u627f\u8a8d\u306f\u6bd4\u8f03\u7684\u65b0\u3057\u304f\u3001\u51e6\u65b9\u30d1\u30bf\u30fc\u30f3\u306f\u306a\u304a\u5909\u5316\u306e\u9014\u4e0a\u306b\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u3068\u306f\u3044\u3048\u3001orforglipron\u306e\u5e02\u5834\u6d78\u900f\u306f\u9069\u5fdc\u75c7\u306b\u3088\u3063\u3066\u7570\u306a\u308b\u3067\u3057\u3087\u3046\u3002\u80a5\u6e80\u5e02\u5834\u3067\u306f\u3001\u7d4c\u53e3\u85ac\u5fd7\u5411\u306e\u5f37\u3044\u9069\u5fdc\u3067\u3042\u308a\u3001\u88fd\u5264\u9762\u30fb\u7528\u6cd5\u9762\u306e\u512a\u4f4d\u6027\u306b\u3088\u308a\u3001\u6ce8\u5c04\u88fd\u5264\u306eGLP-1\u3084\u7d4c\u53e3semaglutide\u306b\u5bfe\u3057\u3066\u6709\u5229\u306a\u7acb\u5834\u3092\u53d6\u308a\u3084\u3059\u3044\u305f\u3081\u3001\u5c0e\u5165\u306f\u3088\u308a\u5f37\u304f\u9032\u3080\u3068\u898b\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u3053\u308c\u306b\u5bfe\u3057\u30012\u578b\u7cd6\u5c3f\u75c5\u5e02\u5834\u3067\u306f\u6ce8\u5c04\u6050\u6016\u75c7\u306f\u85ac\u5264\u9078\u629e\u306e\u4e3b\u8981\u56e0\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u75c5\u72b6\u304c\u9032\u884c\u3059\u308b\u3068\u3001\u591a\u304f\u306e\u60a3\u8005\u306f\u3044\u305a\u308c\u9577\u671f\u7ba1\u7406\u306e\u305f\u3081\u306b\u30a4\u30f3\u30b9\u30ea\u30f3\u3078\u79fb\u884c\u3057\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u6ce8\u5c04\u88fd\u5264\u306eGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306f\u9577\u5e74\u4f7f\u308f\u308c\u3066\u304a\u308a\u3001\u533b\u5e2b\u30fb\u60a3\u8005\u3068\u3082\u306b\u3053\u308c\u3089\u6cbb\u7642\u306b\u6163\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u6ce8\u5c04\u56de\u907f\u306e\u76f8\u5bfe\u7684\u91cd\u8981\u6027\u306f\u4f4e\u4e0b\u3057\u307e\u3059\u3002\u3057\u305f\u304c\u3063\u3066\u3001orforglipron\u306f\u6cbb\u7642\u521d\u671f\u6bb5\u968e\u3067\u306e\u7d4c\u53e3GLP-1\u30d9\u30fc\u30b9\u85ac\u306e\u4f7f\u7528\u3092\u5e83\u3052\u308b\u53ef\u80fd\u6027\u306f\u3042\u308b\u3082\u306e\u306e\u3001\u7cd6\u5c3f\u75c5\u9818\u57df\u306b\u304a\u3051\u308b\u6ce8\u5c04\u88fd\u5264GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u4f7f\u7528\u5168\u4f53\u3078\u306e\u5f71\u97ff\u306f\u9650\u5b9a\u7684\u3068\u4e88\u60f3\u3055\u308c\u307e\u3059\u3002<\/p>\n

\u6642\u9593\u306e\u7d4c\u904e\u3068\u3068\u3082\u306b\u3001orforglipron\u306e\u4f7f\u7528\u306f\u3001\u4e3b\u3068\u3057\u3066\u6ce8\u5c04\u30ec\u30b8\u30e1\u30f3\u306e\u30a2\u30c9\u30d2\u30a2\u30e9\u30f3\u30b9\u7dad\u6301\u306b\u82e6\u52b4\u3059\u308b\u60a3\u8005\u3084\u3001\u4f53\u91cd\u7dad\u6301\u306e\u305f\u3081\u306b\u9577\u671f\u7684\u306a\u6ce8\u5c04\u7d99\u7d9a\u306b\u6d88\u6975\u7684\u306a\u60a3\u8005\u3092\u4e2d\u5fc3\u306b\u3001\u6ce8\u5c04\u88fd\u5264\u304b\u3089\u306e\u9078\u629e\u7684\u30b9\u30a4\u30c3\u30c1\u306b\u3088\u3063\u3066\u5e83\u304c\u3063\u3066\u3044\u304f\u3067\u3057\u3087\u3046\u3002<\/p>\n

\u65e2\u5b58GLP-1\u3078\u306e\u5f71\u97ff<\/strong><\/h3>\n

Q\uff1aorforglipron\u306f\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u30af\u30e9\u30b9\u306b\u304a\u3051\u308b\u7b2c1\u4e16\u4ee3\u30fb\u7b2c2\u4e16\u4ee3\u6cbb\u7642\u85ac\u306e\u5e02\u5834\u306b\u3069\u306e\u3088\u3046\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u304b\u3002<\/p>\n

A\uff1aexenatide\u3084lixisenatide\u306e\u3088\u3046\u306a\u7b2c1\u4e16\u4ee3GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306f\u3001\u3088\u308a\u9ad8\u3044\u6709\u52b9\u6027\u3068\u5229\u4fbf\u6027\u306e\u9ad8\u3044\u6295\u4e0e\u6cd5\u3092\u5099\u3048\u305f\u76ae\u4e0b\u6295\u4e0esemaglutide\u3084tirzepatide\u306a\u3069\u306e\u7b2c2\u4e16\u4ee3\u85ac\u304c\u533b\u5e2b\u306b\u9078\u597d\u3055\u308c\u308b\u3088\u3046\u306b\u306a\u308a\u3001\u3059\u3067\u306b\u6025\u901f\u306a\u7e2e\u5c0f\u3092\u7d4c\u9a13\u3057\u3066\u3044\u307e\u3059\u3002orforglipron\u306e\u4e0a\u5e02\u306f\u3001\u3053\u306e\u6d41\u308c\u3092\u3055\u3089\u306b\u5f37\u3081\u3001\u7279\u306b\u3001\u52b9\u679c\u304c\u9650\u5b9a\u7684\u306a\u6bce\u65e5\u6ce8\u5c04\u3088\u308a\u3082\u7d4c\u53e3\u9078\u629e\u80a2\u3092\u6c42\u3081\u308b\u60a3\u8005\u3084\u81e8\u5e8a\u533b\u306e\u9593\u3067\u3001\u65e7\u6765\u88fd\u54c1\u304b\u3089\u306e\u4f7f\u7528\u79fb\u884c\u3092\u3044\u3063\u305d\u3046\u4fc3\u9032\u3059\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n

\u4e00\u65b9\u3067\u3001\u7b2c2\u4e16\u4ee3\u306e\u6ce8\u5c04\u578bGLP-1\u30d9\u30fc\u30b9\u6cbb\u7642\u306f\u5f37\u529b\u306a\u81e8\u5e8a\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3092\u5099\u3048\u30012\u578b\u7cd6\u5c3f\u75c5\u5e02\u5834\u304a\u3088\u3073\u80a5\u6e80\u5e02\u5834\u306e\u4e21\u65b9\u3067\u975e\u5e38\u306b\u826f\u597d\u306b\u6d78\u900f\u3057\u3066\u3044\u307e\u3059\u3002\u7d4c\u53e3\u85ac\u306b\u306f\u6295\u4e0e\u5229\u4fbf\u6027\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u3088\u308a\u65b0\u3057\u304f\u9ad8\u3044\u6709\u52b9\u6027\u3092\u6301\u3064\u6ce8\u5c04\u88fd\u5264\u304c\u3001\u4e21\u5e02\u5834\u306b\u304a\u3044\u3066\u5f15\u304d\u7d9a\u304d\u3053\u306e\u30af\u30e9\u30b9\u306e\u4e3b\u6d41\u3067\u3042\u308a\u7d9a\u3051\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n

\u7d4c\u53e3\u85ac vs. \u5f8c\u767aGLP-1<\/strong><\/h3>\n

Q\uff1a2\u578b\u7cd6\u5c3f\u75c5\u9818\u57df\u306b\u9650\u3063\u3066\u8a00\u3048\u3070\u3001semaglutide\u306e\u5f8c\u767a\u54c1\u304c\u5229\u7528\u53ef\u80fd\u3068\u306a\u308a\u3001\u3055\u3089\u306b2031\uff5e2032\u5e74\u307e\u3067\u306bretatrutide\u304c\u78ba\u56fa\u305f\u308b\u5730\u4f4d\u3092\u7bc9\u3044\u305f\u5f8c\u3001\u7d4c\u53e3\u85ac\u3001\u7279\u306borforglipron\u306f\u3069\u306e\u3088\u3046\u306b\u63a8\u79fb\u3059\u308b\u3068\u4e88\u60f3\u3057\u307e\u3059\u304b\u3002<\/p>\n

A\uff1a2\u578b\u7cd6\u5c3f\u75c5\u306e\u3088\u3046\u306a\u6709\u52b9\u6027\u4e3b\u5c0e\u306e\u5e02\u5834\u3067\u306f\u3001semaglutide\u5f8c\u767a\u54c1\u304c\u53c2\u5165\u3057\u3001retatrutide\u304c\u5b9a\u7740\u3059\u308b\u4e2d\u3067\u3082\u3001orforglipron\u306f\u6ce8\u5c04\u88fd\u5264\u306b\u5bfe\u3057\u3066\u63a7\u3048\u3081\u306a\u30dd\u30b8\u30b7\u30e7\u30f3\u306b\u3068\u3069\u307e\u308b\u3068\u898b\u3066\u3044\u307e\u3059\u3002<\/p>\n

2\u578b\u7cd6\u5c3f\u75c5\u306b\u304a\u3051\u308b\u51e6\u65b9\u306f\u3001\u8840\u7cd6\u30fb\u975e\u8840\u7cd6\u306e\u4e21\u76ee\u6a19\u306b\u5bfe\u3057\u3066\u5f37\u3044\u30a2\u30a6\u30c8\u30ab\u30e0\u3092\u3082\u305f\u3089\u3059\u6cbb\u7642\u3092\u8ef8\u306b\u7d44\u307f\u7acb\u3066\u3089\u308c\u3066\u304a\u308a\u3001\u305d\u308c\u306b\u5fdc\u3058\u3066tirzepatide\u304c\u5f15\u304d\u7d9a\u304d\u512a\u4f4d\u3092\u4fdd\u3061\u3001retatrutide\u304c\u4e0a\u5e02\u5f8c\u306b\u6ce8\u5c04\u88fd\u5264\u4e3b\u5c0e\u3092\u3055\u3089\u306b\u5f37\u5316\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n

orforglipron\u306f\u3001\u7d76\u98df\u4e0d\u8981\u306e\u6295\u4e0e\u6cd5\u3068\u7d4c\u53e3semaglutide\u306b\u5bfe\u3059\u308b\u76f4\u63a5\u6bd4\u8f03\u3067\u306e\u512a\u4f4d\u6027\u306b\u3088\u308a\u30012\u578b\u7cd6\u5c3f\u75c5\u5e02\u5834\u306e\u7d4c\u53e3\u30bb\u30b0\u30e1\u30f3\u30c8\u3092\u4e3b\u5c0e\u3059\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u3082\u306e\u306e\u3001\u7d4c\u53e3\u85ac\u306f\u3053\u306e\u30af\u30e9\u30b9\u5168\u4f53\u306e\u4f7f\u7528\u306b\u304a\u3044\u3066\u5c11\u6570\u6d3e\u306b\u3068\u3069\u307e\u308b\u3068\u4e88\u60f3\u3055\u308c\u307e\u3059\u3002semaglutide\u5f8c\u767a\u54c1\u306e\u5229\u7528\u53ef\u80fd\u6027\u3084\u3001retatrutide\u306e\u3088\u3046\u306a\u6b21\u4e16\u4ee3\u6ce8\u5c04\u88fd\u5264\u306e\u5f37\u3044\u666e\u53ca\u306a\u3069\u3001\u5e02\u5834\u74b0\u5883\u306e\u5909\u5316\u306f\u3001\u7d4c\u53e3GLP-1\u30d9\u30fc\u30b9\u6cbb\u7642\u306e\u62e1\u5927\u3092\u3055\u3089\u306b\u5236\u7d04\u3059\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n

\u7279\u7b46\u3059\u3079\u304d\u70b9\u3068\u3057\u3066\u3001liraglutide\u5f8c\u767a\u54c1\u306e\u53c2\u5165\u306f\u5f53\u8a72\u6cbb\u7642\u306e\u4f7f\u7528\u62e1\u5927\u3092\u6709\u610f\u306b\u4fc3\u3057\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u3053\u308c\u306f\u3001\u4fa1\u683c\u306e\u4f4e\u3055\u3060\u3051\u3067\u306f2\u578b\u7cd6\u5c3f\u75c5\u5e02\u5834\u306b\u304a\u3044\u3066\u9ad8\u3044\u6709\u52b9\u6027\u3092\u6301\u3064\u9078\u629e\u80a2\u3092\u7f6e\u304d\u63db\u3048\u306b\u304f\u3044\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u540c\u69d8\u306b\u3001semaglutide\u5f8c\u767a\u54c1\u306f\u4e3b\u3068\u3057\u30662030\uff5e2031\u5e74\u307e\u3067\u306e\u4e88\u6e2c\u4e0a\u306e\u6e1b\u5c11\u5206\u3092\u76f8\u6bba\u3059\u308b\u306b\u3068\u3069\u307e\u308a\u3001\u3053\u306e\u30af\u30e9\u30b9\u306f\u5f15\u304d\u7d9a\u304d\u6ce8\u5c04\u88fd\u5264\u4e2d\u5fc3\u3067\u63a8\u79fb\u3057\u3001\u77ed\u671f\u7684\u306b\u306ftirzepatide\u304c\u4e3b\u5c0e\u3057\u3001\u4e0a\u5e02\u304b\u3089\u6570\u5e74\u5f8c\u306b\u306fretatrutide\u304c\u5f90\u3005\u306b\u9996\u4f4d\u306b\u7acb\u3064\u3068\u898b\u8fbc\u307e\u308c\u307e\u3059\u3002<\/p>\n

Clarivate\u306e\u30a2\u30ca\u30ea\u30b9\u30c8\u3067\u3042\u308bShambhavi Shukla\uff08orforglipron\u62c5\u5f53\u3001Lead Healthcare Research and Data Analyst\uff09\u3068Carles Rescasens\uff08retatrutide\u62c5\u5f53\u3001Healthcare Research and Data Analyst\uff09\u304c\u3001\u3053\u308c\u3089\u306e\u53c2\u52a0\u8005\u304b\u3089\u306e\u8cea\u554f\u3078\u306e\u56de\u7b54\u4f5c\u6210\u306b\u5bc4\u4e0e\u3057\u3001\u672c\u30a6\u30a7\u30d3\u30ca\u30fc\u306b\u3082\u767b\u58c7\u3057\u307e\u3057\u305f\u3002<\/em><\/p>\n

\u3053\u306e\u30a6\u30a7\u30d3\u30ca\u30fc\u306f\u3001\u5f53\u793e\u306e\u300c2026 Drugs to Watch\u300d\u30b7\u30ea\u30fc\u30ba\u306e\u7b2c1\u56de\u3068\u3057\u3066\u914d\u4fe1\u3055\u308c\u307e\u3057\u305f\u3002Drugs to watch\u30b7\u30ea\u30fc\u30ba\u306e\u30a6\u30a7\u30d3\u30ca\u30fc\u8996\u8074\u306f<\/em>\u3053\u3061\u3089<\/em><\/a>\u304b\u3089\u3002<\/em><\/p>\n

Cortellis Competitive Intelligence\u304c\u3001\u30e9\u30a4\u30d5\u30b5\u30a4\u30a8\u30f3\u30b9\u5206\u91ce\u306e\u30a4\u30ce\u30d9\u30fc\u30bf\u30fc\u306b\u3088\u308b\u5148\u8aad\u307f\u3068\u3001\u7af6\u5408\u3088\u308a\u65e9\u3044\u6bb5\u968e\u3067\u306e\u30a2\u30bb\u30c3\u30c8\u7372\u5f97\u3092\u3069\u306e\u3088\u3046\u306b\u652f\u63f4\u3059\u308b\u304b\u306b\u3064\u3044\u3066\u306f\u3001\u3053\u3061\u3089\u3092\u3054\u89a7\u304f\u3060\u3055\u3044<\/em>Cortellis Pharma Competitive Intelligence | Clarivate<\/em><\/a><\/p>\n

Clarivate Epidemiology Intelligence\u304c\u3001\u5e02\u5834\u898f\u6a21\u306e\u7cbe\u7dfb\u306a\u628a\u63e1\u3068\u4e88\u6e2c\u3001\u9ad8\u6210\u9577\u6a5f\u4f1a\u306e\u7279\u5b9a\u3068\u512a\u5148\u9806\u4f4d\u4ed8\u3051\u3001\u78ba\u4fe1\u3092\u6301\u3063\u305f\u81e8\u5e8a\u30fb\u5546\u696d\u610f\u601d\u6c7a\u5b9a\u306e\u652f\u63f4\u3001\u305d\u3057\u3066\u4eba\u53e3\u52d5\u614b\u3084\u5e02\u5834\u30c0\u30a4\u30ca\u30df\u30af\u30b9\u306e\u5909\u5316\u3078\u306e\u5148\u884c\u5bfe\u5fdc\u3092\u3069\u306e\u3088\u3046\u306b\u5b9f\u73fe\u3059\u308b\u304b\u306b\u3064\u3044\u3066\u306f\u3001\u3053\u3061\u3089\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\uff1a<\/em>Epidemiology Data, Resources & Analytics | Clarivate<\/em><\/a><\/p>\n

\u203b\u672c\u8a18\u4e8b\u306fClarivate.com\u306e\u82f1\u8a9e\u539f\u6587\u3092AI\u7ffb\u8a33\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u6700\u8fd1\u958b\u50ac\u3057\u305f\u30a6\u30a7\u30d3\u30ca\u30fcDrugs to Watch 2026: Navigating the next wave of GLP-1 evolution and beyond \u306b\u306f\u3001\u53c2\u52a0\u8005\u304b\u3089\u975e\u5e38\u306b\u512a\u308c\u305f\u8cea\u554f\u304c\u5bc4\u305b\u3089\u308c\u307e\u3057\u305f\u3002Clarivate\u306e\u30a2\u30ca\u30ea\u30b9\u30c8\u3067\u3042\u308bCarles Recasens\u3068Shambhavi Shukla\u304c\u3001\u3053\u3053\u3067\u305d\u306e\u56de\u7b54\u3092\u304a\u5c4a\u3051\u3057\u307e\u3059\u3002 Retatrutide: \u73fe\u5728\u5229\u7528\u53ef\u80fd\u306a\u85ac\u5264\u3068\u306e\u6709\u52b9\u6027\u6bd4\u8f03 Q\uff1aRetatrutide\u306b\u3088\u308b\u4f53\u91cd\u6e1b\u5c11\u306f\u3001\u7dcf\u4f53\u91cd\u6e1b\u5c11\u306b\u5360\u3081\u308b\u9664\u8102\u80aa\u4f53\u91cd\u306e\u6e1b\u5c11\u5272\u5408\u3068\u3044\u3046\u89b3\u70b9\u3067\u3001\u73fe\u5728\u5229\u7528\u53ef\u80fd\u306a\u85ac\u5264\u3068\u6bd4\u3079\u3066\u3069\u3046\u3067\u3057\u3087\u3046\u304b\u3002 A\uff1aRetatrutide\u306f\u3001\u73fe\u5728\u306eGLP-1\u85ac\u3068\u6bd4\u8f03\u3057\u3066\u3001\u7dcf\u4f53\u91cd\u6e1b\u5c11\u306b\u5bfe\u3059\u308b\u9664\u8102\u80aa\u4f53\u91cd\u6e1b\u5c11\u306e\u5272\u5408\u306f\u304a\u304a\u3080\u306d\u540c\u7a0b\u5ea6\u3067\u3042\u308b\u3068\u307f\u3089\u308c\u307e\u3059\u30022\u578b\u7cd6\u5c3f\u75c5\u3068\u80a5\u6e80\u3092\u6709\u3059\u308b\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u4f53\u7d44\u6210\u30b5\u30d6\u89e3\u6790(PMID: 40609566)\u3067\u306f\u3001Retatrutide\u306b\u3088\u308b\u9664\u8102\u80aa\u4f53\u91cd\u6e1b\u5c11\u306f\u7dcf\u4f53\u91cd\u6e1b\u5c11\u306e\u7d0438%\u3067\u3042\u308a\u3001semaglutide\u3084tirzepatide\u306a\u3069\u4ed6\u306eGLP-1\u30d9\u30fc\u30b9\u6cbb\u7642\u3067\u5831\u544a\u3055\u308c\u3066\u3044\u308b20\uff5e40%\u306e\u7bc4\u56f2\u5185\u306b\u53ce\u307e\u3063\u3066\u3044\u307e\u3059(PMID: 40609564; 39344838). \u3053\u308c\u3089\u306e\u6240\u898b\u306f\u3001Retatrutide\u306e\u3088\u308a\u9ad8\u3044\u6e1b\u91cf\u52b9\u679c\u304c\u3001\u9664\u8102\u80aa\u4f53\u91cd\u5272\u5408\u306e\u3088\u308a\u5927\u304d\u306a\u640d\u5931\u3092\u4ee3\u511f\u3068\u3057\u3066\u3044\u308b\u308f\u3051\u3067\u306f\u306a\u3044\u3053\u3068\u3092\u793a\u5506\u3057\u3066\u3044\u307e\u3059\u3002 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