\ubc84\uac70\ubcd1\uc73c\ub85c\ub3c4 \uc54c\ub824\uc9c4 \uba74\uc5ed\uae00\ub85c\ube48 A\uc2e0\uc99d(IgAN)\uc740 10~20\ub144\uc5d0 \uac78\uccd0 \ub9d0\uae30 \uc2e0\ubd80\uc804\uc73c\ub85c \uc774\uc5b4\uc9c8 \uc218 \uc788\ub294 \ud76c\uadc0 \uc2e0\uc7a5 \uc790\uac00 \uba74\uc5ed\uc9c8\ud658\uc785\ub2c8\ub2e4. \ud074\ub798\ub9ac\ubca0\uc774\ud2b8\ub294 \uc774 \uc9c8\ud658\uc5d0 \ub300\ud55c \uc0c8\ub85c\uc6b4 \uce58\ub8cc\ubc95\uc758 \ucd9c\ud604\uacfc \uc9c8\ubcd1\uc5d0 \ub300\ud55c \uc778\uc2dd\ud5a5\uc0c1, \uce58\ub8cc\uc728 \ud5a5\uc0c1\uc5d0 \ud798\uc785\uc5b4 IgAN \uce58\ub8cc\uc81c \uc2dc\uc7a5\uc774 2033\ub144\uae4c\uc9c0 \ub9e4\ub144 26%\uc529 \uc131\uc7a5\ud574 2033\ub144\uae4c\uc9c0 42\uc5b5\ub2ec\ub7ec\uc5d0 \uc774\ub97c \uac83\uc774\ub77c \uc804\ub9dd\ud569\ub2c8\ub2e4. \ub610\ud55c, \ubbf8\uad6d\uc5d0\uc11c\ub294 \ud658\uc790 \uc218\uac00 18\ub9cc\uba85, EU5\uc5d0\uc11c\ub294 20\ub9cc\uc744 \ub118\uc744 \uac83\uc73c\ub85c \uc608\uc0c1\ud569\ub2c8\ub2e4. (\ucd9c\ucc98; Clarivate Disease Landscape & Forecast, 2024\ub144 9\uc6d4).<\/p>\n
\ucd5c\uadfc\uae4c\uc9c0 \uc774 \uc9c8\ud658 \uce58\ub8cc\ub294 \ub300\uc99d\uc694\ubc95 \uc704\uc8fc\ub85c \uc774\ub904\uc9c0\uace0 \uc788\uc73c\uba70, \ubbf8\ucda9\uc871 \uc218\uc694\ub85c\ub294 \uc2e0\uc7a5 \uae30\ub2a5 \uc800\ud558\ub97c \ud574\uacb0\ud560 \uc218 \uc788\ub294 \uce58\ub8cc\ubc95- UPCR\uc744 \ubcf4\ub2e4 \ud6a8\uacfc\uc801\uc73c\ub85c \ub0ae\ucd94\uace0 eGFR\uac10\uc18c\ub97c \ub2a6\ucd94\ub294 \uce58\ub8cc\ubc95\uc5d0 \ub300\ud55c \ubbf8\ucda9\uc871 \uc218\uc694\uac00 \uc5ec\uc804\ud788 \ub192\uc2b5\ub2c8\ub2e4. 2021\ub144 TARPEYO\u00ae (\ubd80\ub370\uc18c\ub2c8\ub4dc)\uac00 \ubbf8\uad6d \uc2dc\uc7a5 \ucd9c\uc2dc\ub418\uba74\uc11c \uc804\ud658\uc810\uc774 \ub9c8\ub828\ub418\uc5c8\uc2b5\ub2c8\ub2e4. TARPEYO\u00ae\ub294 Calliditas Therapeutics\uac00 STADA Arzneimittel AG \ubc0f Everest Medicines\uc640 \ud611\ub825\ud558\uc5ec \uac1c\ubc1c\ud55c \uc11c\ubc29\ud615 \ubd80\ub370\uc18c\ub2c8\ub4dc \ucf54\ub974\ud2f0\ucf54\uc2a4\ud14c\ub85c\uc774\ub4dc \uc81c\uc81c\ub85c, \ud604\uc7ac IgAN\uc5d0 \ub300\ud574 \uc2e0\uc7a5 \uae30\ub2a5 \uc190\uc2e4\uc744 \uc720\uc758\ubbf8\ud558\uac8c \uac10\uc18c\uc2dc\ud0a4\ub294-\ud604\uc7ac\ub85c\uc11c\ub294 FDA\uc758 \uc2b9\uc778\uc744 \ubc1b\uc740 \uc720\uc77c\ud55c IgAN \uce58\ub8cc\uc81c\uc785\ub2c8\ub2e4. 3\uc0c1 \uc784\uc0c1\uc2dc\ud5d8\uc5d0\uc11c\ub294 2\ub144 \ub3d9\uc548 \uc704\uc57d \ub300\ube44 \uc2e0\uc7a5 \uc190\uc0c1\uc774 50% \uc801\uc5c8\ub2e4\uace0 \ubcf4\uace0\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n
Calliditas\uc640 \uac19\uc740 \uc791\uc740 \uae30\uc5c5\uc5d0\uac8c \uc0c8\ub85c\uc6b4 \uc758\uc57d\ud488\uc744 \uc0c1\uc6a9\ud654\ud558\uace0 \ud658\uc790\ub4e4\uc774 \uc811\uadfc\ud560 \uc218 \uc788\ub3c4\ub85d \ubcf4\uc7a5\ud558\ub294 \uac83\uc740 \ud070 \ub3c4\uc804 \uacfc\uc81c\uc785\ub2c8\ub2e4. \uc774\ub85c \uc778\ud574 \ub9ce\uc740 \ubc14\uc774\uc624\ud14d \uae30\uc5c5\ub4e4\uc740 \ucd08\uae30 \uc784\uc0c1 \uc2dc\ud5d8 \ub2e8\uacc4\uc5d0\uc11c \ub300\ud615 \uc81c\uc57d\uc0ac\uc5d0 \uc790\uc0ac\uc758 \ud601\uc2e0\uc801\uc778 \uc790\uc0b0\uc744 \ud310\ub9e4\ud558\uac70\ub098 \ub77c\uc774\uc120\uc2a4 \uc544\uc6c3\ud558\ub294 \uacbd\ud5a5\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc774\ub7f0 \uc804\ub7b5\uc758 \uacbd\uc6b0, \ud5a5\ud6c4 \ud601\uc2e0\uc744 \uc704\ud55c \uc790\uae08\uc744 \ub9c8\ub828\ud560 \uc218 \uc788\ub294 \ub300\ubd80\ubd84\uc758 \uc774\uc775\ub3c4 \ud568\uaed8 \ub118\uc5b4\uac00\uac8c \ub429\ub2c8\ub2e4. \ubc18\uba74, Calliditas\ub294 FDA\uc758 \ud76c\uadc0\uc758\uc57d\ud488 \uc9c0\uc815(Orphan Drug Designation) \uc808\ucc28\ub97c \ud65c\uc6a9\ud574 TARPEYO\u00ae\uc5d0 \ub300\ud55c \uac00\uc18d \uc2b9\uc778(Accelerated Approval)\uc744 \ubc1b\ub294 \ub2e4\ub978 \uc804\ub7b5\uc744 \ud0dd\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n
\ucd08\uae30 \uc801\uc751\uc99d\uc740 \ub9e4\uc6b0 \uc81c\ud55c\uc801\uc774\uc5c8\uc9c0\ub9cc, \uae09\uc18d\ud55c \uc9c4\ud589 \uc704\ud5d8\uc774 \uc788\ub294 \uc6d0\ubc1c\uc131 IgAN \uc131\uc778 \ud658\uc790\uc758 \ub2e8\ubc31\ub1e8(\uc18c\ubcc0 \ub0b4 \ub2e8\ubc31\uc9c8 \uc99d\uac00) \uac10\uc18c\uc5d0 \ub300\ud55c \uc801\uc751\uc99d\uc5d0\uc11c \ud6c4\uc18d \uc784\uc0c1\uc2dc\ud5d8 \ub370\uc774\ud130\ub97c \uae30\ubc18\uc73c\ub85c \ud574\ub2f9 \ud658\uc790\uad70\uc758 \uc2e0\uc7a5 \uae30\ub2a5 \uc0c1\uc2e4 \uac10\uc18c\uc5d0 \ub300\ud55c \uc801\uc751\uc99d\uae4c\uc9c0 \ud655\ub300 \uc2b9\uc778\uc744 \ubc1b\uc558\uc2b5\ub2c8\ub2e4. \uc774 \uc57d\ubb3c\uc740 \ub2e4\ub978 \uc801\uc751\uc99d, \uc608\ub97c \ub4e4\uc5b4 \uc790\uac00\uba74\uc5ed \uac04\uc5fc(AIH)\uacfc \uc6d0\ubc1c\uc131 \ub2f4\uc999\uc131 \uac04\uacbd\ubcc0(PBC) \uce58\ub8cc\uc5d0 \ub300\ud55c \uc5f0\uad6c\ub3c4 \uc9c4\ud589 \uc911\uc785\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ub192\uc740 \ube44\uc6a9\uacfc \uc0c8\ub85c\uc6b4 \uacbd\uc7c1\uc790\ub4e4\uc758 \ub4f1\uc7a5\uc73c\ub85c \uc778\ud574 TARPEYO\uc758 IgAN \uce58\ub8cc \uc2dc\uc7a5\uc5d0\uc11c\uc758 \uc9c0\ubc30\ub825\uc740 \ud5a5\ud6c4 \uba87 \ub144 \ub3d9\uc548 \ub3c4\uc804\uc744 \ubc1b\uc744 \uac83\uc785\ub2c8\ub2e4.<\/p>\n
\ud074\ub798\ub9ac\ubca0\uc774\ud2b8\uc758 \ubd84\uc11d\uac00\ub4e4\uc740 2024\ub144 \ube14\ub85d\ubc84\uc2a4\ud130 \uc2e0\uc57d \ubcf4\uace0\uc11c\uc5d0 \ub2e4\ub904\uc9c4 \uc758\uc57d\ud488 \uc911 \uc77c\ubd80\uac00 \ucde8\ud55c \ub9c8\ucf13\uc561\uc138\uc2a4 \uc804\ub7b5\uc744 \ub2e4\ub8ec \uc0c8\ub85c\uc6b4 \ubcf4\uace0\uc11c \uc2dc\ub9ac\uc988\ub85c\uc11c \ucc28\ud2b8\ub97c \uc791\uc131\ud588\uc2b5\ub2c8\ub2e4. IgAN\uc744 \ub458\ub7ec\uc2fc \uad11\ubc94\uc704\ud55c \uacbd\uc7c1\ud658\uacbd, \ud658\uae09 \ud658\uacbd \ubd84\uc11d\uc744 \ud3ec\ud568\ud574 TARPEYO\/Kinpeygo\uc758 \uaddc\uc81c\uc640 \uad00\ub828\ub41c \uc5ec\uc815\uc5d0 \ub300\ud55c \uc804\uccb4 \ubcf4\uace0\uc11c\ub97c \ud655\uc778\ud558\uc2dc\ub824\uba74 \uc774\uacf3<\/a>\uc744 \ub20c\ub7ec\uc8fc\uc2dc\uae30 \ubc14\ub78d\ub2c8\ub2e4. \ub610\ud55c, AREXVY \ubc0f ABRYSVO\u2122<\/a> \uc640 Eylea\u00ae HD<\/a>\uc5d0 \ub300\ud55c \uc815\ubcf4\ub3c4 \uac01\uac01\uc758 \ub9c1\ud06c\ub97c \ud1b5\ud574 \ud655\uc778\ud574\uc8fc\uc2ed\uc2dc\uc624.<\/p>\n \ud074\ub798\ub9ac\ubca0\uc774\ud2b8\uac00 \ud601\uc2e0\uc801\uc778 \uae30\uc5c5\ub4e4\uc774 \uaca9\ubcc0\ud558\ub294 \uae00\ub85c\ubc8c \ub9c8\ucf13 \uc561\uc138\uc2a4 \ud658\uacbd\uc744 \ud5e4\uccd0\ub098\uac00\ub294\ub370 \uc5b4\ub5bb\uac8c \ub3c4\uc6c0\uc744 \uc8fc\ub294\uc9c0 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc2dc\ub824\uba74 \uc774\uacf3<\/a>\uc744 \ub20c\ub7ec \ud655\uc778\ud574\ubcf4\uc2dc\uae30 \ubc14\ub78d\ub2c8\ub2e4.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":" \ubc84\uac70\ubcd1\uc73c\ub85c\ub3c4 \uc54c\ub824\uc9c4 \uba74\uc5ed\uae00\ub85c\ube48 A\uc2e0\uc99d(IgAN)\uc740 10~20\ub144\uc5d0 \uac78\uccd0 \ub9d0\uae30 \uc2e0\ubd80\uc804\uc73c\ub85c \uc774\uc5b4\uc9c8 \uc218 \uc788\ub294 \ud76c\uadc0 \uc2e0\uc7a5 \uc790\uac00 \uba74\uc5ed\uc9c8\ud658\uc785\ub2c8\ub2e4. \ud074\ub798\ub9ac\ubca0\uc774\ud2b8\ub294 \uc774 \uc9c8\ud658\uc5d0 \ub300\ud55c \uc0c8\ub85c\uc6b4 \uce58\ub8cc\ubc95\uc758 \ucd9c\ud604\uacfc \uc9c8\ubcd1\uc5d0 \ub300\ud55c \uc778\uc2dd\ud5a5\uc0c1, \uce58\ub8cc\uc728 \ud5a5\uc0c1\uc5d0 \ud798\uc785\uc5b4 IgAN \uce58\ub8cc\uc81c…<\/p>\n","protected":false},"author":45,"featured_media":350444,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_links_to":"","_links_to_type":0,"footnotes":""},"categories":[1315],"tags":[],"class_list":["post-353258","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-life-sciences-healthcare","clarivate-industry-life-sciences-and-healthcare","clarivate-product-family-cortellis"],"acf":[],"lang":"ko","translations":{"ko":353258},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"pll_sync_post":[],"_links":{"self":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/posts\/353258","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/users\/45"}],"replies":[{"embeddable":true,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/comments?post=353258"}],"version-history":[{"count":5,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/posts\/353258\/revisions"}],"predecessor-version":[{"id":408432,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/posts\/353258\/revisions\/408432"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/media\/350444"}],"wp:attachment":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/media?parent=353258"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/categories?post=353258"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/tags?post=353258"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}