{"id":2206,"date":"2021-08-20T13:28:06","date_gmt":"2021-08-20T04:28:06","guid":{"rendered":"https:\/\/clarivate.com\/ko\/?p=2206"},"modified":"2021-08-20T13:28:06","modified_gmt":"2021-08-20T04:28:06","slug":"asco_2021_kr","status":"publish","type":"post","link":"https:\/\/clarivate.com\/life-sciences-healthcare\/ko\/blog\/asco_2021_kr\/","title":{"rendered":"ASCO 2021 \uc885\uc591\ud559 10\ub300 \uc774\uc288"},"content":{"rendered":"

ASCO 2021 \uc885\uc591\ud559 10\ub300 \uc774\uc288<\/p>\n

\ud074\ub798\ub9ac\ubca0\uc774\ud2b8\uc758 \uc885\uc591\ud559 \uc804\ubb38\uac00\ub4e4\uc740 \ubbf8\uad6d\uc784\uc0c1\uc885\uc591\ud559\ud68c<\/em>(ASCO)\uc5d0\uc11c \ubc1c\ud45c\ub41c 2,400\uac1c \uc774\uc0c1\uc758 \ucd08\ub85d\uc744 \ubd84\uc11d\ud558\uc5ec \uc57d\ubb3c \uce58\ub8cc \ub3d9\ud5a5\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc0c1\uc704 \uc5f0\uad6c 10\uac74\uc744 \uc120\uc815\ud588\uc2b5\ub2c8\ub2e4. \uc774 \uae30\uc0ac\ub294 \ub17c\ubb38\uc744 \ud1b5\ud574 \ubc1c\uacac\ud55c \ud765\ubbf8\ub85c\uc6b4 \uc0ac\uc2e4\uacfc \ub370\uc774\ud130\uc5d0 \uad00\ud55c \ubd84\uc11d, \uc0dd\uba85\uacfc\ud559 \uad00\uacc4\uc790\ub4e4\uc744 \uc704\ud55c \uc2dc\uc0ac\uc810\uc744 \uacf5\uc720\ud569\ub2c8\ub2e4.<\/em><\/p>\n

\u201c\ud615\ud3c9\uc131: \ubaa8\ub4e0 \ud658\uc790\uc5d0\uac8c. \ud56d\uc0c1. \uc5b4\ub514\uc5d0\uc11c\ub098\u201d<\/em><\/strong><\/p>\n

\ubbf8\uad6d\uc784\uc0c1\uc885\uc591\ud559\ud68c (\uc774\ud558, ASCO) \uc5f0\ub840\ud559\uc220\ub300\ud68c\ub294 \uc885\uc591\ud559\uacfc \uad00\ub828\ub41c \uac00\uc7a5 \ud070 \uaddc\ubaa8\uc758 \ud589\uc0ac\ub85c \ub9e4\ub144 \uac1c\ucd5c\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ucf54\ub85c\ub09819 \ub300\uc720\ud589\uc73c\ub85c \uc778\ud574 \uc804\ub144\ub3c4\uc640 \ub9c8\ucc2c\uac00\uc9c0\ub85c \uc62c\ud574 \ud589\uc0ac\ub294 6\uc6d4 4\uc77c\ubd80\ud130 8\uc77c\uae4c\uc9c0 \ud654\uc0c1\uc73c\ub85c \uac1c\ucd5c\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc62c\ud574\uc758 \uc8fc\uc81c\ub294 \u201c\ud615\ud3c9\uc131: \ubaa8\ub4e0 \ud658\uc790\uc5d0\uac8c, \ud56d\uc0c1, \uc5b4\ub514\uc5d0\uc11c\ub098\u201d\ub85c \ud5a5\ud6c4 \uc5f0\uad6c\uc5d0\uc11c \uc9d1\uc911\ud574\uc57c \ud560 \uc601\uc5ed\uc758 \uc6b0\uc120\uc21c\uc704\ub97c \uc815\ud558\uace0, \uc811\uadfc\uc131 \ud5a5\uc0c1\uc744 \uc704\ud55c \uc758\ub8cc \uc18c\uc678 \uc9d1\ub2e8\uc758 \uc784\uc0c1 \uc5f0\uad6c \ud3ec\ud568\uc758 \uc911\uc694\uc131\uc744 \uac15\uc870\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc57d\ubb3c \uc2dc\uc7a5\uc5d0 \uc0c1\ub2f9\ud55c \uc601\ud5a5\uc744 \ubbf8\uce60 \uac83\uc73c\ub85c \uc608\uc0c1\ub418\ub294 \uce58\ub8cc\ubc95\uc744 \uac80\ud1a0\ud55c \ube14\ub85d\ubc84\uc2a4\ud130 \uc2e0\uc57d\ubcf4\uace0\uc11c(Drugs to WatchTM<\/sup>)<\/a>\uc2dc\ub9ac\uc988\uc758 \uc77c\ud658\uc73c\ub85c, \ud074\ub798\ub9ac\ubca0\uc774\ud2b8\uc758 \uc885\uc591\ud559 \uc804\ubb38\uac00\ub4e4\uc740 \ud504\ub808\uc820\ud14c\uc774\uc158\uc5d0 \ucc44\ud0dd\ub41c 2,400 \uac1c \uc774\uc0c1\uc758 \ucd08\ub85d \uc911 \ucd5c\uc6b0\uc218 \uc5f0\uad6c\ub97c \uc120\uc815\ud588\uc2b5\ub2c8\ub2e4. \uc774\ubc88 \uae30\uc0ac\uc5d0\uc11c\ub294 \uc120\uc815\ub41c \ucd08\ub85d\uc5d0 \ub300\ud55c \ubd84\uc11d\uacfc \uc0dd\uba85\uacfc\ud559 \uad00\uacc4\uc790\ub97c \uc704\ud55c \ud575\uc2ec \ub0b4\uc6a9\uc744 \uc81c\uc2dc\ud569\ub2c8\ub2e4.<\/p>\n

ASCO 2021\uc5d0\uc11c\ub294 \uc885\uc591\ud559 \uc2dc\uc7a5\uc758 \uc2a4\ud399\ud2b8\ub7fc\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce60 \ub9ce\uc740 \uc18c\uc2dd\uc774 \uacf5\uac1c\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc62c\ud574 \ud559\ud68c\uc5d0\uc11c \uac00\uc7a5 \ub450\ub4dc\ub7ec\uc9c4 \uacbd\ud5a5 \uc911 \ud558\ub098\ub294 \uc57d\ubb3c \uce58\ub8cc\uc758 \uc635\uc158\uc774 \uc5c6\ub294 \uba87\uba87 \ub09c\uce58\uc131 \uc554\uc744 \ud3ec\ud568\ud558\uc5ec \uc9c8\ubcd1\uc758 \ucd08\uae30 \ub2e8\uacc4 (\ub610\ub294 \ubcf4\uc870\uc694\ubc95)\uc5d0\uc11c \ud45c\uc801 \uce58\ub8cc\uc5d0 \ub300\ud55c \ub370\uc774\ud130\ub97c \ubcf4\uace0\ud558\ub294 \ucd08\ub85d\uc774 \ud070 \ube44\uc911\uc744 \ucc28\uc9c0\ud588\ub2e4\ub294 \uac83\uc785\ub2c8\ub2e4.<\/p>\n

\uc774\ubc88 \ud559\ud68c\uc5d0\uc11c \uc5b8\uae09\ub41c \uc8fc\uc694 \ub370\uc774\ud130\uc5d0 \ub300\ud55c \uc2ec\uce35\uc801\uc778 \ubd84\uc11d\uc744 \uc704\ud574 \ud074\ub798\ub9ac\ubca0\uc774\ud2b8 \uc804\ubb38\uac00 \ud300\uc758 \uc758\uacac\uc744 \ucc38\uace0\ud558\uc2dc\uae30 \ubc14\ub78d\ub2c8\ub2e4.<\/p>\n

    \n
  1. \ud2f0\uc13c\ud2b8\ub9ad(Tecentriq), \uc808\uc81c \uac00\ub2a5\ud55c \ucd08\uae30 \ube44\uc18c\uc138\ud3ec\ud3d0\uc554(resectable early-stage NSCLC)\uc5d0 \ub300\ud55c \ubcf4\uc870\uc694\ubc95\uc73c\ub85c\uc11c\uc758 \uac00\ub2a5\uc131\uc744 \ubcf4\uc5ec\uc90c <\/strong><\/li>\n<\/ol>\n

    \ud2f0\uc13c\ud2b8\ub9ad\uc740 \ubb34\ubcd1\uc0dd\uc874\uae30\uac04<\/em>(DFS)\uc758 \uc0c1\ub2f9\ud55c \uc774\uc810\uc5d0 \uae30\ubc18\ud558\uc5ec \uc808\uc81c \uac00\ub2a5\ud55c \ucd08\uae30 \ube44\uc18c\uc138\ud3ec\uc131 \ud3d0\uc554 \ud658\uc790\uc5d0 \ub300\ud55c \uc0ac\uc6a9 \uc2b9\uc778\uc744 \ud68d\ub4dd\ud55c \ucd5c\ucd08\uc758 \uba74\uc5ed\uad00\ubb38\uc5b5\uc81c\uc81c\uac00 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/em><\/p>\n

    \ubc30\uacbd<\/strong>:<\/strong>\u00a0\uc5ec\ub7ec \uac1c\uc758 \uba74\uc5ed\uad00\ubb38\uc5b5\uc81c\uc81c\uac00 \uc808\uc81c \uac00\ub2a5\ud55c NSCLC\uc5d0 \ub300\ud55c \ubcf4\uc870\uc694\ubc95\uc73c\ub85c \ud3c9\uac00\ubc1b\uace0 \uc788\uc2b5\ub2c8\ub2e4. 2021\ub144 3\uc6d4, \uc808\uc81c \uc218\uc220\uacfc \ubcf4\uc870 \ud654\ud559 \uc694\ubc95\uc744 \ubc1b\uc740 \ubcd1\uae30 IB-IIIA NSCLC \ud658\uc790\ub4e4\uc744 \ub300\uc0c1\uc73c\ub85c \ud55c \ub85c\uc288(Roche)\uc758 \ud2f0\uc13c\ud2b8\ub9ad\uacfc \ucd5c\uc801 \uc9c0\uc9c0\uc694\ubc95(BSC)\uc744 \ube44\uad50\ud55c \uc784\uc0c1 3\uc0c1 IMpower010 \uc5f0\uad6c\uc5d0\uc11c \ud2f0\uc13c\ud2b8\ub9ad\uc740 \ubb34\ubcd1\uc0dd\uc874\uae30\uac04\uc758 1\ucc28 \ud3c9\uac00\uc9c0\ud45c\ub97c \ucda9\uc871\ud558\uc600\uace0, \ud574\ub2f9 \uc870\uac74\uc5d0\uc11c \uc720\uc758\ubbf8\ud55c \uc784\uc0c1\uc801 \uc774\uc810\uc744 \ubcf4\uc5ec\uc8fc\ub294 \uccab \ubc88\uc9f8 \uba74\uc5ed\uad00\ubb38\uc5b5\uc81c\uc81c\uac00 \ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

    ASCO\uc5d0\uc11c \uc0c8\ub85c \ubc1c\ud45c\ub41c \ub0b4\uc6a9:<\/strong>\u00a0\uc5f0\uad6c \uacb0\uacfc<\/a>\uc5d0 \ub530\ub974\uba74 \uc885\uc591 \uc138\ud3ec PD-L1 \ubc1c\ud604\uc774 1% \uc774\uc0c1\uc778 \ubcd1\uae30 II-IIIA \ud658\uc790\uad70(HR 0.66, P = 0.0039)\uacfc \ubcd1\uae30 II-IIIA NSCLC \ubb34\uc791\uc704 \ud658\uc790\uad70(HR 0.79, P = 0.0205) \ubaa8\ub450\uc5d0\uc11c \ud2f0\uc13c\ud2b8\ub9ad\uc758 \ubb34\ubcd1\uc0dd\uc874\uae30\uac04\uc774 \ucd5c\uc801 \uc9c0\uc9c0\uc694\ubc95\uc5d0 \ube44\ud558\uc5ec \ud06c\uac8c \uc99d\uac00\ud558\uc600\uc2b5\ub2c8\ub2e4. \uc774 \ubd84\uc11d \ub2f9\uc2dc, \ubb34\ubcd1\uc0dd\uc874\uae30\uac04\uc740 \uc804\uccb4 ITT \ub300\uc0c1\uad70(intent-to-treat population) (\ubcd1\uae30 IB-IIIA)\uc5d0\uc11c \uc911\uc694 \uacbd\uacc4\uc120\uc744 \ub118\uc9c0 \uc54a\uc558\uace0 \uc804\uccb4 \uc0dd\uc874\uc728 \ub370\uc774\ud130\ub294 \ubbf8\uc644\uc131\uc774\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

      \n
    1. \ub9b0\ud30c\uc790(Lynparza), \uc0dd\uc2dd\uc138\ud3ec BRCA1\/2 \ubcc0\uc774(germline BRCA1\/2 mutations) \uace0\uc704\ud5d8 HER2 \uc74c\uc131 \uc870\uae30 \uc720\ubc29\uc554(HER2-negative early-stage breast cancer) \ud658\uc790\uc5d0\uac8c\uc11c \uc704\uc57d \ub300\ube44 \uc6b0\uc6d4\ud55c \ud6a8\uacfc<\/strong><\/li>\n<\/ol>\n

      OlympiA \uc5f0\uad6c \ub370\uc774\ud130\ub85c \ub9b0\ud30c\uc790\uac00 \ucd08\uae30 \uc720\ubc29\uc554 \uc2dc\uc7a5\uc5d0 \uc788\ub294 \ub2e4\ub978 \uacbd\uc7c1\uc790\ub4e4\uc744 \ubb3c\ub9ac\uce60 \uc218 \uc788\uc744\uae4c? <\/em><\/p>\n

      \ubc30\uacbd<\/strong>:<\/strong>\u00a02021\ub144 2\uc6d4, \uc544\uc2a4\ud2b8\ub77c\uc81c\ub124\uce74(AstraZeneca)\ub294 \ub9b0\ud30c\uc790\uac00 \uc784\uc0c1 3\uc0c1 OlympiA \uc5f0\uad6c\uc5d0\uc11c BRCA \ubcc0\uc774, \uace0\uc704\ud5d8 HER2 \uc74c\uc131 \uc870\uae30 \uc720\ubc29\uc554 \ud658\uc790\ub97c \ub300\uc0c1\uc73c\ub85c \uc704\uc57d \ub300\ube44 \uc6b0\uc218\ud55c \uce68\uc2b5\uc801 \ubb34\ubcd1\uc0dd\uc874\uae30\uac04(iDFS)\uc758 1\ucc28 \ud3c9\uac00\uc9c0\ud45c\ub97c \ucda9\uc871\ud588\ub2e4\uace0 \ubc1c\ud45c\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

      ASCO\uc5d0\uc11c \uc0c8\ub85c \ubc1c\ud45c\ub41c \ub0b4\uc6a9:<\/strong>\u00a0 \uc544\uc2a4\ud2b8\ub77c\uc81c\ub124\uce74\ub294 \uc774\ubc88 \uc5f0\uad6c\uc640 \uad00\ub828\ud558\uc5ec \ucd94\uac00 \ub370\uc774\ud130\ub97c \ubc1c\ud45c\ud588\uc2b5\ub2c8\ub2e4. OlympiA \uc5f0\uad6c\ub294 \ub2e4\ub978 PARP \uc5b5\uc81c\uc81c\uac00 \ud3c9\uac00\ub418\uc9c0 \uc54a\ub294 \ubcf4\uc870\uc694\ubc95 \uc870\uac74\uc5d0\uc11c \ub9b0\ud30c\uc790\ub97c \uc2dc\ud5d8 \uc911\uc5d0 \uc788\uc2b5\ub2c8\ub2e4. \ub9b0\ud30c\uc790\uac00 \ud604 \uc0c1\ud669\uc5d0\uc11c \uc2b9\uc778\uc744 \ud655\ubcf4\ud560 \uacbd\uc6b0, \uae30\uc874\uc758 \ud56dPD-1\/PD-L1 \uc5b5\uc81c\uc81c\uc778 \ud2f0\uc13c\ud2b8\ub9ad\uacfc \ud0a4\ud2b8\ub8e8\ub2e4(Keytruda)\uc640\uc758 \uce58\uc5f4\ud55c \uacbd\uc7c1\uc5d0 \uc9c1\uba74\ud558\uac8c \ub420 \uac83\uc785\ub2c8\ub2e4. PD-1\/PD-L1 \uc81c\uc81c\uac00 \uc2ec\uce35\uc801\uc774\uace0 \uc7a5\uae30\uc801\uc778 \uc784\uc0c1 \ubc18\uc751\uc744 \uc720\ubc1c\ud560 \uac00\ub2a5\uc131\uc774 \uc788\ub2e4\ub294 \uac83\uc744 \uac10\uc548\ud560 \ub54c, \uc758\uc0ac\ub4e4\uc740 PARP \uc5b5\uc81c\uc81c\ubcf4\ub2e4\ub294 \uba74\uc5ed\uad00\ubb38\uc5b5\uc81c\uc81c\ub97c \ucc98\ubc29\ud558\ub294 \uacbd\ud5a5\uc774 \uc788\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uac8c\ub2e4\uac00 OlympiA \uc5f0\uad6c\ub294 BRCA1\/2 \ubcc0\uc774 \uc0bc\uc911 \uc74c\uc131 \uc720\ubc29\uc554(BRCA1\/2-mutated triple-negative breast cancer) \ud658\uc790\ub4e4\ub85c \uc774\ub8e8\uc5b4\uc9c4 \ubd80\ubd84 \ud658\uc790\uad70\uc744 \ud0c0\uac9f\uc73c\ub85c \ub450\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

      \uc804\ub9dd<\/strong>:<\/strong>\u00a0 \uc704\uc640 \uac19\uc740 \uc7a0\uc7ac\uc801 \uac78\ub9bc\ub3cc\uc5d0\ub3c4 \ubd88\uad6c\ud558\uace0 \uc758\uc0ac\ub4e4\uc740 HER2 \uc74c\uc131 BRCA1\/2 \ubcc0\uc774 \uc9c4\ud589\uc131 \uc720\ubc29\uc554(BRCA1\/2-mutated triple-negative breast cancer) \ud658\uc790\uad70\uc5d0\uc11c \uc785\uc99d\ub41c \ub9b0\ud30c\uc790\uc758 \ud6a8\ub2a5\ub54c\ubb38\uc5d0 \uc774 \uc2dc\ud5d8\uc758 \uacb0\uacfc\ub97c \uace0\ub300\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc784\uc0c1\uc2dc\ud5d8\uc774 \uc131\uacf5\ud560 \uacbd\uc6b0, OlympiA \uc5f0\uad6c \uacb0\uacfc\ub294 \ucd08\uae30 \ub2e8\uacc4 \uc9c8\ubcd1\uc5d0\uc11c\uc758 \ub9b0\ud30c\uc790\uc758 \ucc98\ubc29 \ubc94\uc704\ub97c \ud655\ub300\ub97c \ub4b7\ubc1b\uce68\ud558\uace0 \uc720\ubc29\uc554\uc5d0\uc11c \uc801\uaca9 \ud658\uc790\uad70\uc744 \ud06c\uac8c \ud655\uc7a5\ud560 \uc218 \uc788\uc744 \uac83\uc785\ub2c8\ub2e4.
      \n
      \n3. \ud0a4\ud2b8\ub8e8\ub2e4(Keytruda), \uc2e0\uc7a5\uc554(renal cell carcinoma) \ubcf4\uc870\uc694\ubc95\uc5d0 \ud6a8\uacfc <\/strong><\/p>\n

      \ud0a4\ud2b8\ub8e8\ub2e4\uac00 \uc2e0\uc7a5\uc554 \ubcf4\uc870\uc694\ubc95\uc73c\ub85c\uc11c \ud56d <\/em>PD-1\/PD-L1 \uce58\ub8cc\uc81c\uc758 \ubb38\uc744 \uc5f4 \uac83\uc778\uac00?<\/em><\/p>\n

      \ubc30\uacbd<\/strong>:<\/strong>\u00a02021\ub144 4\uc6d4, \uba38\ud06c(Merck)\ub294 KEYNOTE-564 \uc5f0\uad6c\uac00 \uc704\uc57d\uacfc \ub300\ube44\ud558\uc5ec 1\ucc28 \ud3c9\uac00\uc9c0\ud45c\uc778 \ubb34\ubcd1\uc0dd\uc874\uae30\uac04(DFS)\uc744 \ucda9\uc871\ud588\ub2e4\uace0 \ubc1c\ud45c\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uc2e0\uc7a5\uc554 \ubcf4\uc870\uc694\ubc95\uc5d0\uc11c\uc758 \ud56dPD-1\/PD-L1 \uce58\ub8cc\uc81c\uc758 \uccab \ubc88\uc9f8 \uae0d\uc815\uc801 \uacb0\uacfc\uc785\ub2c8\ub2e4.<\/p>\n

      ASCO\uc5d0\uc11c \uc0c8\ub85c \ubc1c\ud45c\ub41c \ub0b4\uc6a9:<\/strong>\u00a0\uba38\ud06c(Merck)\ub294 \uc2e0\uc7a5\uc554 \ud658\uc790\uc758 \uc2e0\uc7a5\uc808\uc81c\uc220 \ud6c4 \ubcf4\uc870\uc694\ubc95\uc73c\ub85c \ud0a4\ud2b8\ub8e8\ub2e4\ub97c \ud3c9\uac00\ud558\ub294 KEYNOTE-564 \uc5f0\uad6c\uc758 \uc608\ube44 \ubd84\uc11d \ub0b4\uc6a9\uc744 \ubc1c\ud45c\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

      \uc804\ub9dd<\/strong>:<\/strong>\u00a0\uc2e0\uc7a5\uc554\uc758 \ubcf4\uc870\uc694\ubc95\uc740 \ubbf8\uac1c\ucc99 \uc2dc\uc7a5\uc774\uc790 \uba74\uc5ed\uad00\ubb38\uc5b5\uc81c\uc81c\uc758 \uc7a0\uc7ac\uc801\uc778 \uc131\uc7a5 \uacbd\ub85c\ub97c \ubcf4\uc5ec\uc90d\ub2c8\ub2e4. \uc774\ubc88 \ub370\uc774\ud130<\/a>\ub294 \uc2e0\uc7a5\uc554\uc5d0\uc11c\uc758 \ud0a4\ud2b8\ub8e8\ub2e4\uc758 \uae30\ud68c\ub97c \ud655\ub300\ud558\uace0 \ud5a5\ud6c4 \uc9c4\ud589\uc131 \uc2e0\uc7a5\uc554 1\ucc28 \uce58\ub8cc\ub97c \uc704\ud55c \uc778\ub77c\uc774\ud0c0(Inlyta)\uc640\uc758 \ubcd1\uc6a9\uc694\ubc95\uc73c\ub85c \ud0a4\ud2b8\ub8e8\ub2e4\uac00 \ud604\uc7ac \uc2b9\uc778\ubc1b\uc740 \uc801\uc751\uc99d\uc744 \ud655\uc7a5\uc2dc\ud0ac \uac83\uc785\ub2c8\ub2e4.<\/p>\n

      \ud0a4\ud2b8\ub8e8\ub2e4\uc758 \ubcf4\uc870\uc694\ubc95\uc73c\ub85c\uc11c\uc758 \ud655\uc7a5\uc740 \uc2e0\uc7a5\uc554\uc5d0 \ub300\ud55c \uce58\ub8cc\uc81c \uc2dc\uc7a5\uc744 \uc7ac\uad6c\ucd95 \ud560 \uc218 \uc788\uc73c\uba70, \uc774 \uc801\uc751\uc99d\uc758 \ub77c\uc774\ud504\uc0ac\uc774\ud074 \uad00\ub9ac\uc5d0 \uc911\uc694\ud55c \uae30\ud68c\uac00 \ub420 \uac83\uc785\ub2c8\ub2e4.<\/p>\n

        \n
      1. \uc635\ub514\ubcf4(Opdivo), \uc2dd\ub3c4\uc554(esophageal cancer) \ub610\ub294 \uc704\uc2dd\ub3c4\uc811\ud569\ubd80\uc554(gastroesophageal junction cancer) \uc808\uc81c\uc220 \ud6c4 \ubcf4\uc870\uc694\ubc95\uc73c\ub85c\uc11c \ud070 \ud6a8\ub2a5<\/strong><\/li>\n<\/ol>\n

        CheckMate-577 \uc5f0\uad6c \ub370\uc774\ud130\ub85c \ubb34\uc7a5\ud55c \uc635\ub514\ubcf4\ub294 \ucd08\uae30\ub2e8\uacc4 \uc2dd\ub3c4\uc554 \ub610\ub294 \uc704\uc2dd\ub3c4\uc811\ud569\ubd80\uc554\uc758 \uce58\ub8cc \ubc29\uc2dd\uc744 \ubc14\uafc0 \uc218 \uc788\uc2b5\ub2c8\ub2e4. <\/em><\/p>\n

        \ubc30\uacbd<\/strong>:<\/strong>\u00a02021\ub144 5\uc6d4, \uc784\uc0c1 3\uc0c1 CheckMate-577 \uc5f0\uad6c\uc758 \ubb34\ubcd1\uc0dd\uc874\uae30\uac04(DFS) \uacb0\uacfc\uc5d0 \uae30\ubc18\ud558\uc5ec FDA\ub294 \uc635\ub514\ubcf4\ub97c \uc120\ud589\ud654\ud559\uc694\ubc95(neoadjuvant chemoradiotherapy)\uc744 \ubc1b\uc740 \uc794\ub958 \ubcd1\ub9ac\ud559\uc801 \uc9c8\ud658(residual pathologic disease)\uc744 \uac00\uc9c4 \uc644\uc804 \uc808\uc81c\uc220\uc744 \ubc1b\uc740 \uc2dd\ub3c4\uc554 \ub610\ub294 \uc704\uc2dd\ub3c4\uc811\ud569\ubd80\uc554 \ud658\uc790\uc758 \uce58\ub8cc\ub97c \uc704\ud55c \ubcf4\uc870\uc694\ubc95\uc73c\ub85c \uc2b9\uc778\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

        ASCO\uc5d0\uc11c \uc0c8\ub85c \ubc1c\ud45c\ub41c \ub0b4\uc6a9:<\/strong>\u00a0\u00a0\uc784\uc0c1\uc2dc\ud5d8\uc758 \ucd94\uac00 \ub370\uc774\ud130<\/a>\ub294 \uc635\ub514\ubcf4 \ubcf4\uc870\uc6a9\ubc95\uacfc \uc704\uc57d \uc0ac\uc774\uc758 \uc6d0\uaca9 \ubb34\uc804\uc774 \uc0dd\uc874\uc728(distant metastasis-free survival) \uc911\uc559\uac12\uc5d0 \ub9e4\uc6b0 \uc720\uc758\ubbf8\ud55c \ucc28\uc774\ub97c \ubcf4\uc774\uace0 \uc788\uc2b5\ub2c8\ub2e4(\uac01\uac01 28.3\uac1c\uc6d4\uacfc 17.6\uac1c\uc6d4, HR 0.74). \uc774 \ub370\uc774\ud130\ub294 \ud658\uc790\ub4e4\uc758 \uc0b6\uc758 \uc9c8\uc774 \uc720\uc9c0\ub418\uc5c8\uc73c\uba70 \uc635\ub514\ubcf4\uc758 \uc548\uc804\uc131 \ud504\ub85c\ud544\uc774 \uc784\uc0c1 \ud658\uacbd\uc5d0\uc11c \uad00\ub9ac \uac00\ub2a5\ud588\uc74c\uc744 \uc2dc\uc0ac\ud569\ub2c8\ub2e4.<\/p>\n

        \uc804\ub9dd<\/strong>: <\/strong>\uc774\ub7ec\ud55c \uacb0\uacfc\ub294 \ud604\uc7ac \ub2e4\ub978 \ud45c\uc801 \uce58\ub8cc\uc81c\uac00 \uc2b9\uc778\ub418\uc9c0 \uc54a\uc740 \uc2dd\ub3c4\uc554 \ub610\ub294 \uc704\uc2dd\ub3c4\uc811\ud569\ubd80 \uc808\uc81c\uc220 \ubcf4\uc870\uc694\ubc95\uc5d0\uc11c \uc635\ub514\ubcf4\ub97c \uc0c8\ub85c\uc6b4 \uce58\ub8cc \ud45c\uc900\uc73c\ub85c \uc124\uc815\ud558\ub294\ub370 \ub3c4\uc6c0\uc774 \ub420 \uac83\uc785\ub2c8\ub2e4. \uc8fc\ubaa9\ud560 \uc810\uc740, \uc635\ub514\ubcf4\uac00 \uc545\uc131 \ud751\uc0c9\uc885(malignant melanoma) \ud658\uc790\ub4e4\uc744 \uc704\ud55c \ubcf4\uc870\uc694\ubc95\uc73c\ub85c\ub3c4 \uc2b9\uc778\ub418\uc5c8\ub2e4\ub294 \uac83\uc785\ub2c8\ub2e4.<\/p>\n

          \n
        1. \ube0c\ub9ac\uc2a4\ud1a8 \ub9c8\uc774\uc5b4\uc2a4 \uc2a4\ud034\ube0c(Bristol Myers Squibb, BMS), \uc635\ub514\ubcf4(Opdivo) \ubcd1\uc6a9\uc694\ubc95\uc744 \uc9c4\ud589\uc131 \ub610\ub294 \uc804\uc774\uc131 \uc2dd\ub3c4\ud3b8\ud3c9\uc0c1\ud53c\uc138\ud3ec\uc554(esophageal squamous cell carcinoma, ESCC)\uc758 1\ucc28 \uce58\ub8cc\uc81c\ub85c \ud3ec\uc9c0\uc154\ub2dd <\/strong><\/li>\n<\/ol>\n

          CheckMate-648 \uc5f0\uad6c \ub370\uc774\ud130\ub97c \ud1b5\ud574 \uc774\uc804\uc5d0 \uce58\ub8cc\ub418\uc9c0 \uc54a\uc740 \ud658\uc790\uc5d0 \ub300\ud55c \uc635\ub514\ubcf4 \ubcd1\uc6a9\uc694\ubc95\uc774 \uc2b9\uc778\ub420 \uc218 \uc788\uc9c0\ub9cc, \uc774 \ubd80\ubd84\uc5d0\uc11c\ub294 \ud0a4\ud2b8\ub8e8\ub2e4\uc640\uc758 \uacbd\uc7c1\uc5d0 \uc9c1\uba74\ud560 \uac83\uc785\ub2c8\ub2e4.<\/em><\/p>\n

          \ubc30\uacbd<\/strong>:<\/strong>\u00a0\u00a0<\/strong>\ub2e4\ub978 \ub9ce\uc740 \uc885\uc591 \uc801\uc751\uc99d\uacfc \ub9c8\ucc2c\uac00\uc9c0\ub85c \uc2dd\ub3c4\uc554\uc5d0 \ub300\ud55c \ubcd1\uc6a9\uc694\ubc95\uc774 \uac1c\ubc1c \uc911\uc5d0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

          ASCO\uc5d0\uc11c \uc0c8\ub85c \ubc1c\ud45c\ub41c \ub0b4\uc6a9:<\/strong>\u00a0BMS\ub294 \uc808\uc81c\ubd88\uac00\ub2a5\ud55c \uc9c4\ud589\uc131 \ub610\ub294 \uc804\uc774\uc131 \uc2dd\ub3c4\ud3b8\ud3c9\uc0c1\ud53c\uc138\ud3ec\uc554(ESCC)\uc5d0 \ub300\ud55c 1\ucc28 \uce58\ub8cc\ubc95\uc73c\ub85c \uc635\ub514\ubcf4+\uc5ec\ubcf4\uc774(Yervoy) \ubcd1\uc6a9\uacfc \uc635\ub514\ubcf4+\ud654\ud559\uc694\ubc95 \ubcd1\uc6a9\uc744 \ud3c9\uac00\ud55c \uc784\uc0c1 3\uc0c1 CheckMate-648 \uc5f0\uad6c \uacb0\uacfc\ub97c \uacf5\uac1c\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

          \uc804\ub9dd<\/strong>: <\/strong>\uc131\uacf5\ud560 \uacbd\uc6b0, \uc774 \uc784\uc0c1 \uc5f0\uad6c\ub294 \uc635\ub514\ubcf4+\uc5ec\ubcf4\uc774 \ubc0f \uc635\ub514\ubcf4+\ud654\ud559\uc694\ubc95 \ubcd1\uc6a9\uc5d0 \ub300\ud55c FDA \uc2b9\uc778\uc73c\ub85c \uc774\uc5b4\uc9c8 \uac00\ub2a5\uc131\uc774 \ub192\uc73c\uba70, \uc774 \uacbd\uc6b0 \uc635\ub514\ubcf4\uac00 \uc804\uc774\uc131 ESCC \uce58\ub8cc\ubc95\uc758 \ucd08\uae30 \ub77c\uc778\uc73c\ub85c \uc774\ub3d9\ud558\uac8c \ub429\ub2c8\ub2e4(\ud604\uc7ac\ub294 \ud50c\ub8e8\uc624\ub85c\ud53c\ub9ac\ubbf8\ub518\uacfc \ubc31\uae08 \uae30\ubc18 \ud654\ud559\uc694\ubc95 \uc774\ud6c4 \uc0ac\uc6a9\uc73c\ub85c \uc2b9\uc778\ub428). \ud558\uc9c0\ub9cc, \ud0a4\ud2b8\ub8e8\ub2e4\uc640 \ud654\ud559\uc694\ubc95\uc758 \ubcd1\uc6a9\uc774 \uad6d\uc18c \uc9c4\ud589\uc131 \ub610\ub294 \uc804\uc774\uc131 \uc2dd\ub3c4\uc554\uacfc \uc704\uc2dd\ub3c4\uc811\ud569\ubd80\uc554\uc744 \ub300\uc0c1\uc73c\ub85c \uc774\ubbf8 \uc2b9\uc778\ubc1b\uc740 \uc810\uc744 \uac10\uc548\ud558\uba74 (CheckMate-648 \uc5f0\uad6c\uc5d0\uc11c \uc870\uc0ac\ub41c \uac83\ubcf4\ub2e4 \ub354 \uad11\ubc94\uc704\ud55c \uc801\uc751\uc99d), \uc635\ub514\ubcf4 \ubcd1\uc6a9\uc694\ubc95\uc740 \ud0a4\ud2b8\ub8e8\ub2e4\uc640 \uce58\uc5f4\ud55c \uacbd\uc7c1\uc5d0 \uc9c1\uba74 \ud560 \uac00\ub2a5\uc131\uc774 \ub192\uc2b5\ub2c8\ub2e4.<\/p>\n

            \n
          1. \ud0a4\ud2b8\ub8e8\ub2e4(Keytruda)+\ud5c8\uc149\ud2f4(Herceptin) \ubc0f \ud654\ud559\uc694\ubc95\uc758 \ubcd1\uc6a9\uc774 \uce58\ub8cc\ub418\uc9c0 \uc54a\uc740 \uc804\uc774\uc131 HER2 \uc591\uc131 \uc704\uc554(metastatic HER2+ gastric) \ub610\ub294 \uc704\uc2dd\ub3c4\uc811\ud569\ubd80 \uc120\uc554(gastroesophageal junction adenocarcinoma)\uc5d0 \ub300\ud55c \uc0c8\ub85c\uc6b4 \uce58\ub8cc \uc635\uc158\uc744 \uc81c\uacf5<\/strong><\/li>\n<\/ol>\n

            \uc774 \uc0bc\uc911 \ubcd1\uc6a9\uc694\ubc95\uc740 \uc804\uccb4 \ubc18\uc751\ub960<\/em>(ORR)\uacfc \ubc18\uc751 \uae30\uac04\uc744 \uae30\ubc18\uc73c\ub85c 1\ucc28 \uce58\ub8cc \uc635\uc158\uc744 \ud655\ub300\ud569\ub2c8\ub2e4.<\/em><\/p>\n

            \ubc30\uacbd<\/strong>:<\/strong>\u00a0\u00a02021\ub144 5\uc6d4, \uc784\uc0c1 3\uc0c1 KEYNOTE-811 \uc5f0\uad6c\uc758 \uc911\uac04 \ub370\uc774\ud130\ub97c \uae30\ubc18\uc73c\ub85c FDA\ub294 \uce58\ub8cc\ub418\uc9c0 \uc54a\uc740 \uc804\uc774\uc131 HER2 \uc591\uc131 \uc704\uc554 \ub610\ub294 \uc704\uc2dd\ub3c4\uc811\ud569\ubd80\uc554\uc5d0 \ub300\ud55c \ud0a4\ud2b8\ub8e8\ub2e4+\ud5c8\uc149\ud2f4 \ubc0f \ud654\ud559\uc694\ubc95 \ubcd1\uc6a9\uc5d0 \ub300\ud55c \uac00\uc18d \uc2b9\uc778\uc744 \ud5c8\uac00\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

            ASCO\uc5d0\uc11c \uc0c8\ub85c \ubc1c\ud45c\ub41c \ub0b4\uc6a9:<\/strong>\u00a0\uba38\ud06c(Merck)\ub294 \uc804\uc774\uc131 HER2 \uc591\uc131 \uc704\uc554 \ub610\ub294 \uc704\uc2dd\ub3c4\uc811\ud569\ubd80\uc554\uc5d0 \ub300\ud55c 1\ucc28 \uce58\ub8cc\uc81c\ub85c \ud0a4\ud2b8\ub8e8\ub2e4+\ud5c8\uc149\ud2f4 \ubc0f \ud654\ud559\uc694\ubc95\uc758 \ubcd1\uc6a9\uc744 \ud3c9\uac00\ud558\ub294 \uc784\uc0c1 3\uc0c1 KEYNOTE-811 \uc5f0\uad6c\uc758 \ucd5c\ucd08 \ub370\uc774\ud130\ub97c \uacf5\uac1c\ud588\uc2b5\ub2c8\ub2e4. \uc774\ubc88 \uc784\uc0c1 \uacb0\uacfc<\/a>\uc5d0 \ub530\ub974\uba74 \ud45c\uc900 \uce58\ub8cc\uc778 \ud5c8\uc149\ud2f4+\ud654\ud559\uc694\ubc95\uc5d0 \ube44\ud574 \uc804\uccb4 \ubc18\uc751\ub960(ORR)\uc774 \uc720\uc758\ubbf8\ud558\uac8c \ud5a5\uc0c1\ud558\uc600\uace0 (\uac01\uac01 74%\uc640 52%, P = 0.00006), \uba74\uc5ed\uad00\ubb38\uc5b5\uc81c\uc81c \uc694\ubc95\uacfc \ub300\ub4f1\ud55c \ubc18\uc751 \uc9c0\uc18d\uae30\uac04 \uc911\uc559\uac12(median duration of response) (\uac01\uac01 10.6 \uac1c\uc6d4\uacfc 9.5 \uac1c\uc6d4)\uacfc \uc548\uc804\uc131 \ud504\ub85c\ud544\uc744 \ubcf4\uc600\uc2b5\ub2c8\ub2e4. \uc774 \ubcd1\uc6a9 \uc694\ubc95\uc5d0 \ub300\ud55c FDA\uc758 \uac00\uc18d \uc2b9\uc778\uc740 \uc885\uc591 \ubc18\uc751\uacfc \ubc18\uc751 \uae30\uac04\uc744 \uae30\ubc18\uc73c\ub85c \uc774\ub904\uc84c\uc2b5\ub2c8\ub2e4.<\/p>\n

            \uc804\ub9dd<\/strong>: <\/strong>\uc774 \uc0c8\ub85c\uc6b4 \ubcd1\uc6a9 \uc694\ubc95\uc740 \uc804\uc774\uc131 HER2 \uc591\uc131 \uc704\uc554 \ub610\ub294 \uc704\uc2dd\ub3c4\uc811\ud569\ubd80\uc554\uc758 \uc81c\ud55c\ub41c \uce58\ub8cc \uc635\uc158\uacfc \uc88b\uc9c0 \uc54a\uc740 \uc608\ud6c4\ub97c \uace0\ub824\ud560 \ub54c, \ud658\uc790\ub4e4\uc5d0\uac8c \uc0c1\ub2f9\ud55c \uc774\uc810\uc744 \uc81c\uacf5\ud560 \uac83\uc73c\ub85c \ubcf4\uc785\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc77c\ubd80 \uc885\uc591 \uc804\ubb38\uc758\ub4e4\uc740 \ud574\ub2f9 \ubcd1\uc6a9\uc694\ubc95\uc744 \uc784\uc0c1 \uc2e4\uc2b5\uc5d0 \ud655\ub300 \uc801\uc6a9\ud558\uae30\uc5d0 \uc55e\uc11c \ubb34\uc9c4\ud589 \uc0dd\uc874\uae30\uac04(PFS)\uacfc \uc804\uccb4 \uc0dd\uc874\uae30\uac04(OS) \uacb0\uacfc(\uacf5\ub3d9 1\ucc28 \ud3c9\uac00\uc9c0\ud45c)\ub97c \uae30\ub2e4\ub9b4 \uac00\ub2a5\uc131\uc774 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

              \n
            1. LAG-3 (\ub810\ub77c\ud2c0\ub9ac\ub9d9, relatlimab)\uacfc PD-1 (\uc635\ub514\ubcf4, Opdivo) \ubcd1\uc6a9\uc5d0 \ub300\ud55c \ucd5c\ucd08 \uc784\uc0c1 3\uc0c1 \ub370\uc774\ud130 \ubc0f \uc545\uc131 \ud751\uc0c9\uc885(malignant melanoma)\uc758 \uc0c8\ub85c\uc6b4 \uce58\ub8cc \uc635\uc158<\/strong><\/li>\n<\/ol>\n

              \ube0c\ub9ac\uc2a4\ud1a8 \ub9c8\uc774\uc5b4\uc2a4 \uc2a4\ud034\ube0c<\/em>(Bristol Myers Squibb, BMS)\uc758 \ub810\ub77c\ud2c0\ub9ac\ub9d9\/\uc635\ub514\ubcf4\ub294 \uc545\uc131\ud751\uc0c9\uc885\uc5d0 \ub300\ud55c PD-1\/CTLA-4 \ubcd1\uc6a9\uc694\ubc95(\uc635\ub514\ubcf4\/\uc5ec\ubcf4\uc774)\uc774 \uc810\uc720\ud558\uace0 \uc788\ub294 \uc2dc\uc7a5\uc5d0 \uc9c4\uc785\ud560 \uc900\ube44\uac00 \ub418\uc5b4 \uc788\uc2b5\ub2c8\ub2e4.<\/em><\/p>\n

              \ubc30\uacbd<\/strong>:<\/strong> 2021\ub144 3\uc6d4, BMS\ub294 RELATIVITY-047\uc774 \uc635\ub514\ubcf4 \ub2e8\ub3c5 \uc694\ubc95\uacfc \ube44\uad50\ud558\uc5ec \ubb34\uc9c4\ud589 \uc0dd\uc874\uae30\uac04(PFS)\uc758 1\ucc28 \ud3c9\uac00\uc9c0\ud45c\ub97c \ucda9\uc871\ud588\ub2e4\uace0 \ubc1c\ud45c\ud588\uc73c\uba70, \uc774\ub294 \uc885\uc591\ud559\uc5d0\uc11c LAG-3\uc640 PD-1 \ubcd1\uc6a9\uc694\ubc95\uc5d0 \ub300\ud55c \ucd5c\ucd08\uc758 \uae0d\uc815\uc801\uc778 \uc784\uc0c1 3\uc0c1 \uc2dc\ud5d8 \uacb0\uacfc\uc785\ub2c8\ub2e4.<\/p>\n

              ASCO\uc5d0\uc11c \uc0c8\ub85c \ubc1c\ud45c\ub41c \ub0b4\uc6a9:<\/strong>\u00a0BMS\ub294 \uc774\uc804\uc5d0 \uce58\ub8cc\ub418\uc9c0 \uc54a\uc740 \uc808\uc81c \ubd88\uac00\ub2a5\ud558\uac70\ub098 \uc804\uc774\uc131\uc758 \uc545\uc131 \ud751\uc0c9\uc885\uc5d0\uc11c \ub810\ub77c\ud2c0\ub9ac\ub9d9(LAG-3)+\uc635\ub514\ubcf4(PD-1) \ubcd1\uc6a9\uc694\ubc95\uacfc \uc635\ub514\ubcf4 \ub2e8\ub3c5 \uc694\ubc95\uc744 \ube44\uad50\ud55c \uc784\uc0c1 2\/3\uc0c1 RELATIVITY-047 \uc5f0\uad6c\uc758 \uacb0\uacfc\ub97c \ucc98\uc74c\uc73c\ub85c \uacf5\uac1c\ud588\uc2b5\ub2c8\ub2e4 (\uc790\uc138\ud55c \ucd08\ub85d\uc740 \uc5ec\uae30<\/a>\uc640 \uc5ec\uae30<\/a>\uc5d0\uc11c \ud655\uc778\ud558\uc138\uc694). \ubcd1\uc6a9\uc694\ubc95\uc740 \uc635\ub514\ubcf4 \ub2e8\ub3c5 \uc694\ubc95\uc5d0 \ube44\ud574 5\uac1c\uc6d4 \uac1c\uc120\ub41c PFS \uc911\uc559\uac12\uc744 \ubcf4\uc600\uc2b5\ub2c8\ub2e4 (\uac01\uac01 10.1\uac1c\uc6d4\uacfc 4.6 \uac1c\uc6d4).<\/p>\n

              \uc804\ub9dd<\/strong>:<\/strong> BMS\uc758 \uc0c8\ub85c\uc6b4 \uace0\uc815 \uc6a9\ub7c9 LAG-3\/PD-1 \ubcd1\uc6a9\uc694\ubc95\uc5d0 \ub300\ud55c \uc808\ub300 \ud45c\uc900\uc778 \uc804\uccb4 \uc0dd\uc874\uae30\uac04(OS) \ub370\uc774\ud130\ub294 \uc544\uc9c1 \ubcf4\uace0\ub418\uc9c0 \uc54a\uc558\uc9c0\ub9cc, \uae30\uc874\uc758 CTLA-4\/PD-1 \ubcd1\uc6a9\uc694\ubc95\uacfc \uc720\uc0ac\ud55c \ud6a8\ub2a5\uc744 \ub098\ud0c0\ub0b4\ub294 \uac83\uc73c\ub85c \ubcf4\uc785\ub2c8\ub2e4 (\uc9c1\uc811 \ube44\uad50 \uac00\ub2a5\ud55c \ub370\uc774\ud130\ub294 \uc5c6\uc74c). \ub354\uc6b1\uc774 \uc774\ub294 \ub354 \uc548\uc804\ud558\uace0 \uc6b0\uc218\ud55c \ub0b4\uc57d\uc131\uc744 \uac00\uc9c4 \ub300\uc548\uc73c\ub85c \uc54c\ub824\uc838 \uc788\uc2b5\ub2c8\ub2e4. \ubd80\uc791\uc6a9 \ud504\ub85c\ud544 \ub610\ud55c \uc6b0\uc218\ud558\uae30 \ub54c\ubb38\uc5d0 CTLA-4\/PD-1 \ubcd1\uc6a9\uc694\ubc95\uc73c\ub85c\ubd80\ud130 \uc774\ub3d9\ud558\ub294 \uacbd\uc6b0\ub3c4 \uc608\uc0c1\ub429\ub2c8\ub2e4.<\/p>\n

                \n
              1. \uc778\uc0c1\uc801\uc778 \uc804\uccb4 \ubc18\uc751\ub960(ORR) \ub370\uc774\ud130\ub85c \ubb34\uc7a5\ud55c \uc2e4\ud0c0\ucea1\ud0c0\uc9c4 \uc624\ud1a0\ub958\uc140(ciltacabtagene autoleucel)\uc774 \uce58\ub8cc \uc774\ub825\uc774 \ub9ce\uc740 \ub2e4\ubc1c\uc131 \uace8\uc218\uc885(multiple myeloma)\uc5d0 \ub300\ud55c \uce58\ub8cc \ud45c\uc900\uc774 \ub420 \uc218 \uc788\uc744\uae4c? <\/strong><\/li>\n<\/ol>\n

                \uc2e4\ud0c0\ucea1\ud0c0\uc9c4 \uc624\ud1a0\ub958\uc140\uc740 \uce58\ub8cc\ubc1b\uc740 \uc774\ub825\uc774 \ub9ce\uc740 \ub2e4\ubc1c\uc131 \uace8\uc218\uc885 \ud658\uc790\ub4e4\uc744 \uc704\ud55c <\/em>BCMA \ud45c\uc801 \uc694\ubc95\uc758 \ud6a8\ub2a5 \uae30\uc900\uc744 \ub192\uc600\uc2b5\ub2c8\ub2e4.<\/em><\/p>\n

                \ubc30\uacbd<\/strong>:<\/strong>\u00a0\ucd5c\uadfc \uc2b9\uc778\ub41c B-cell maturation antigen (BCMA) \ud45c\uc801 \uce58\ub8cc\uc81c\uc778 \uc544\ubca0\ud06c\ub9c8(Abecma; \ub2e4\ubc1c\uc131 \uace8\uc218\uc885\uc5d0 \ub300\ud55c FDA \uc2b9\uc778\uc744 \ud655\ubcf4\ud55c \ucd5c\ucd08\uc758 CAR-T \uc138\ud3ec \uce58\ub8cc\uc81c)\uc640 \ube0c\ub80c\ub819(Blenrep; \ud56d\uccb4-\uc57d\ubb3c \uc811\ud569\uccb4)\ub294 \ucd5c\uc18c 4\ubc88\uc758 \uce58\ub8cc\ub97c \ubc1b\uc740 \uc774\ub825\uc774 \uc788\ub294 \ud658\uc790\uc758 \uce58\ub8cc\uc5d0 \uc4f0\uc785\ub2c8\ub2e4. 2020\ub144 12\uc6d4\uacfc 2021\ub144 4\uc6d4\uc5d0 \uc580\uc13c(Janssen)\uc740 BCMA \ud45c\uc801 CAR-T \uc138\ud3ec \uce58\ub8cc\uc81c\uc778 \uc2e4\ud0c0\ucea1\ud0c0\uc9c4 \uc624\ud1a0\ub958\uc140\uc5d0 \ub300\ud574 \uc784\uc0c1 1b\/2\uc0c1 CARTITUDE-1 \uc5f0\uad6c\ub97c \ud1a0\ub300\ub85c FDA\uc5d0 \uc0dd\ubb3c\uc758\uc57d\ud488 \ud5c8\uac00 \uc2e0\uccad(BLA)\uc744, EMA\uc5d0 \ud310\ub9e4 \ud5c8\uac00 \uc2e0\uccad\uc11c(MAA)\ub97c \uac01\uac01 \uc81c\ucd9c\ud588\uc2b5\ub2c8\ub2e4. \ud574\ub2f9 \uc784\uc0c1\uc2dc\ud5d8\uc5d0\uc11c \uc774 \uce58\ub8cc\uc81c\ub294 \uc0ac\uc804 \uce58\ub8cc \uc774\ub825\uc774 \ub9ce\uc740 \ub2e4\ubc1c\uc131 \uace8\uc218\uc885 \ud658\uc790\uc5d0\uac8c\uc11c 97%\uc758 \uc804\uccb4 \ubc18\uc751\ub960(ORR)\uc744 \ubcf4\uc600\uc2b5\ub2c8\ub2e4.<\/p>\n

                ASCO\uc5d0\uc11c \uc0c8\ub85c \ubc1c\ud45c\ub41c \ub0b4\uc6a9:<\/strong>\u00a0\ub2e4\uc911 \ucf54\ud638\ud2b8 \uc784\uc0c1 2\uc0c1 CARTITUDE-2 \uc5f0\uad6c\uc5d0\uc11c\uc758 \uc2e4\ud0c0\ucea1\ud0c0\uc9c4 \uc624\ud1a0\ub958\uc140 \ub370\uc774\ud130<\/a>\ub3c4 \ub9c8\ucc2c\uac00\uc9c0\ub85c \uc778\uc0c1\uc801\uc785\ub2c8\ub2e4. \uc774 \uc81c\uc81c\ub294 1~3\ud68c\uc758 \uce58\ub8cc \ud6c4 \uc7ac\ubc1c\uc131\/\ubd88\uc751\uc131 \ud658\uc790\ub4e4\uc5d0 \uc788\uc5b4 95%\uc758 \uc804\uccb4 \ubc18\uc751\ub960(ORR)\uc744 \ubcf4\uc600\uc2b5\ub2c8\ub2e4 (75%\uc758 \uc5c4\uaca9\ud55c \uc644\uc804\uad00\ud574(sCR) \ub610\ub294 \uc644\uc804\uad00\ud574(CR) \ud3ec\ud568). \ucd94\uc801 \uad00\ucc30 \uae30\uac04\uc758 \uc911\uc559\uac12(median follow-up)\uc740 \uc9e7\uc9c0\ub9cc (\ub370\uc774\ud130 \ucef7\uc624\ud504\uc2dc 5.8\uac1c\uc6d4), \uc774\ubc88 2\uc0c1 \uc5f0\uad6c\uc5d0\uc11c \uad00\ucc30\ub41c \ucd08\uae30 \ubc0f \uc2ec\uce35 \ubc18\uc751\uc740 \ub9e4\uc6b0 \uae0d\uc815\uc801\uc774\uba70 \uc2dc\uc7a5\uc5d0 \uc9c4\uc785\ud560 \uacbd\uc6b0 \uc2e4\ud0c0\ucea1\ud0c0\uc9c4 \uc624\ud1a0\ub958\uc140\uc774 \uc88b\uc740 \ubc18\uc751\uc744 \uc5bb\uc744 \uc870\uc9d0\uc744 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4.<\/p>\n

                \uc804\ub9dd<\/strong>:<\/strong>\u00a0 \uc774\uc911\ud2b9\uc774\uc131 BCMA \ubc0f CD3 \ud45c\uc801 \ud56d\uccb4 \ud14c\ud074\ub9ac\uc2a4\ud0c0\ub9d9(teclistamab)\uc5d0 \ub300\ud574 \uc5c5\ub370\uc774\ud2b8\ub41c \uc784\uc0c1 1\uc0c1 \ub370\uc774\ud130\uac00 ASCO \ubc0f \uc580\uc13c(Janssen)\uc5d0\uc11c \uacf5\uc720\ub418\uba74\uc11c \ub2e4\ubc1c\uc131 \uace8\uc218\uc885\uc5d0 \ub300\ud55c BCMA \ud45c\uc801 \uc694\ubc95 \uc2dc\uc7a5\uc774 \ub354\uc6b1 \uc5ed\ub3d9\uc801\uc73c\ub85c \ubcc0\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

                  \n
                1. \uce7c\ud038\uc2a4(Calquence) vs. \uc784\ube0c\ub8e8\ube44\uce74(Imbruvica)? \ud5a5\ud6c4 BTK \uc5b5\uc81c\uc81c \uacbd\uc7c1\uc744 \uc77c\uc73c\ud0ac \uc9c1\uc811 \ube44\uad50 \ub370\uc774\ud130 <\/strong><\/li>\n<\/ol>\n

                  \uce7c\ud038\uc2a4\uc758 \uc548\uc804\uc131 \ud504\ub85c\ud544\uc740 \ub9cc\uc131\ub9bc\ud504\uad6c\uc131\ubc31\ud608\ubcd1<\/em>(chronic lymphocytic leukemia, CLL)\uc758 \ud45c\uc900 \uce58\ub8cc\uc81c\uc778 \uc784\ube0c\ub8e8\ube44\uce74\uc640\uc758 \ucc28\ubcc4\ud654\uc5d0 \ucda9\ubd84\ud55c\uac00?<\/em><\/p>\n

                  \ubc30\uacbd<\/strong>:<\/strong>\u00a0\u00a0\uc580\uc13c((Janssen)\/\uc560\ube0c\ube44(AbbVie)\uc758 \uc784\ube0c\ub8e8\ube44\uce74\uc640 \uc544\uc2a4\ud2b8\ub77c\uc81c\ub124\uce74(AstraZeneca)\uc758 \uce7c\ud038\uc2a4\ub294 \uc784\uc0c1 3\uc0c1 ELEVATE-RR \uc5f0\uad6c\uc5d0\uc11c \ud3c9\uac00\uc911\uc778 \uacbd\uad6c\uc6a9 BTK \uc5b5\uc81c\uc81c\uc785\ub2c8\ub2e4. \uce7c\ud038\uc2a4\ub294 CLL \uce58\ub8cc\uc5d0 \ub300\ud574 \uaddc\uc81c \uc2b9\uc778\uc744 \ubc1b\uc740 \ub450 \ubc88\uc9f8 BTK \uc5b5\uc81c\uc81c\ub85c, \ud604\uc7ac \ud45c\uc900 \uce58\ub8cc\uc81c\uc778 \uc784\ube0c\ub8e8\ube44\uce74\uac00 \uc8fc\ub3c4\ud558\uace0 \uc788\ub294 \uacbd\uc7c1 \uc2dc\uc7a5\uc5d0 \uc9c4\uc785\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

                  ASCO\uc5d0\uc11c \uc0c8\ub85c \ubc1c\ud45c\ub41c \ub0b4\uc6a9:<\/strong>\u00a0\u00a0\ub370\uc774\ud130\ub294 \uace0\uc704\ud5d8 \uc7ac\ubc1c\uc131 \ub610\ub294 \ubd88\uc751\uc131 CLL\uc5d0 \ub300\ud574 \uce7c\ud038\uc2a4\uc640 \uc784\ube0c\ub8e8\ube44\uce74\ub97c \ucd5c\ucd08\ub85c \uc9c1\uc811 \ube44\uad50\ud55c \uc5f0\uad6c\uc5d0\uc11c \uacf5\uc720\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc544\uc2a4\ud2b8\ub77c\uc81c\ub124\uce74\uc758 \ube44\uc5f4\ub4f1\uc131 \uc784\uc0c1\uc2dc\ud5d8\uc740 \ub3d9\ub4f1\ud55c \ud6a8\ub2a5\uacfc \ud568\uaed8 \ud6c4\uae30 \uce58\ub8cc \ub77c\uc778\uc5d0\uc11c \uce7c\ud038\uc2a4\uc758 \uc0ac\uc6a9\uc744 \ucd09\uc9c4\ud558\ub294 \ub370 \ub3c4\uc6c0\uc774 \ub420 \uc8fc\uc694 \uc548\uc804\uc131\uacfc \ub0b4\uc57d\uc131\uc5d0\uc11c\uc758 \ucc28\uc774\uc640 \ud568\uaed8 \ub3d9\ub4f1\ud55c \ud6a8\ub2a5\uc744 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4. ELEVATE-RR \uc5f0\uad6c\uc5d0\uc11c \uce7c\ud038\uc2a4\ub294 \uc591\ucabd\uad70\uc5d0\uc11c \ubaa8\ub450 38.4\uac1c\uc6d4\uc758 \ubb34\uc9c4\ud589 \uc0dd\uc874\uae30\uac04(PFS) \uc911\uc559\uac12\uc744 \ubcf4\uc774\uba70 \uc784\ube0c\ub8e8\ube44\uce74\ubcf4\ub2e4 \uc5f4\ub4f1\ud558\uc9c0 \uc54a\uc740 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4 (\uc804\uccb4 \uc0dd\uc874\uae30\uac04(OS) \uc911\uc559\uac12\uc5d0 \ub3c4\ub2ec\ud558\uc9c0\ub294 \uc54a\uc74c). \ud2b9\ud788, \uce7c\ud038\uc2a4\ub294 \ubaa8\ub4e0 \ub4f1\uae09\uc758 \uc2ec\ubc29\uc138\ub3d9(2\ucc28 \ud3c9\uac00\uc9c0\ud45c)\uc5d0\uc11c \uc784\ube0c\ub8e8\ube44\ud0c0\ubcf4\ub2e4 \ud1b5\uacc4\uc801\uc73c\ub85c \uc6b0\uc218\ud55c \uacb0\uacfc\uc640 \uc801\uc740 \ucd9c\ud608 \ube48\ub3c4\ub97c \ub098\ud0c0\ub0b4\uc5c8\uace0, \uacb0\uacfc\uc801\uc73c\ub85c \uce58\ub8cc \uc911\ub2e8\uc758 \uacbd\uc6b0\uac00 \uc801\uc5c8\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc0c8\ub85c\uc6b4 BTK \uc5b5\uc81c\uc81c\uc5d0\uc11c \ub450\ud1b5\uacfc \uae30\uce68\uc740 \ub354 \ud754\ud558\uac8c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.<\/p>\n

                  \uc804\ub9dd<\/strong>: <\/strong>\uc2ec\uc7a5\ub3c5\uc131\uacfc \ucd9c\ud608\uc740 \ud604\uc7ac\uae4c\uc9c0 \uc784\ube0c\ub8e8\ube44\uce74\uc758 \uc57d\uc810\uc774 \ub418\uc5b4\uc654\uace0, \uc774\ubc88 \ub370\uc774\ud130\ub294 \uce7c\ud038\uc2a4\uc758 \ud5a5\ud6c4 \uc2dc\uc7a5 \ud761\uc218 \ubc0f \uc7ac\ubc1c\uc131 \ub610\ub294 \ubd88\uc751\uc131 \ud658\uc790\uc5d0\uc758 \uc801\uc6a9\uc5d0 \ub300\ud55c \uae0d\uc815\uc801\uc778 \uc870\uc9d0\uc744 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4. \uc758\uc0ac\ub4e4\uc740 \uc9c1\uc811 \ube44\uad50 \ub370\uc774\ud130\ub97c \uc6d0\ud558\uace0 \uc788\uc9c0\ub9cc, \ud655\uace0\ud55c \uc785\uc9c0\uc758 \uc784\ube0c\ub8e8\ube44\uce74\ub97c \ub118\uc5b4\ub728\ub9ac\ub294 \uac83\uc740 \uc5b4\ub824\uc6b8 \uac83\uc73c\ub85c \ubcf4\uc785\ub2c8\ub2e4.<\/p>\n

                  10.177<\/sup>Lu-PSMA-617\uc5d0 \ub300\ud55c VISION \uc5f0\uad6c \ub370\uc774\ud130\uac00 \uce58\ub8cc \uc774\ub825\uc774 \ub9ce\uc740 \uc804\uc774\uc131 \uac70\uc138\uc800\ud56d\uc131 \uc804\ub9bd\uc120\uc554(metastatic castration-resistant prostate cancer, mCRPC) \ud658\uc790\ub4e4\uc744 \uc704\ud55c \uc0c8\ub85c\uc6b4 \uce58\ub8cc \uc635\uc158\uc744 \uc81c\uacf5<\/strong><\/p>\n

                  \uc758\ub8cc \uc11c\ube44\uc2a4\uc5d0\uc11c \uc18c\uc678\ub41c \ud658\uc790 \ud558\uc704 \uc9d1\ub2e8\uc744 \ub300\uc0c1\uc73c\ub85c \ud558\ub294 \ubc14\uc774\uc624\ub9c8\ucee4 \uae30\ubc18 \uc811\uadfc \ubc29\uc2dd\uc774 \uc77c\uc0c1\uc801\uc778 \uc9c4\ub8cc\uc5d0\uc11c \uc5bc\ub9c8\ub098 \ub110\ub9ac \ucc44\ud0dd\ub420 \uac83\uc778\uac00<\/em>? <\/em><\/p>\n

                  \ubc30\uacbd<\/strong>:<\/strong>\u00a02021\ub144 3\uc6d4, \ub178\ubc14\ud2f0\uc2a4(Novartis)\ub294 177<\/sup>Lu-PSMA-617\uc774 \ubbf8\ucda9\uc871 \uc218\uc694\uac00 \ub192\uc740 \uce58\ub8cc \uc774\ub825\uc774 \ub9ce\uc740 \ud658\uc790\uad70\uc758 \ud45c\uc900 \uce58\ub8cc\uc640 \ube44\uad50\ud558\uc5ec \uc804\uccb4 \uc0dd\uc874\uae30\uac04(OS)\uacfc \ubc29\uc0ac\uc120\ud559\uc801 \ubb34\uc9c4\ud589 \uc0dd\uc874\uae30\uac04(rPFS)\uc758 \ub450\uac00\uc9c0 1\ucc28 \ud3c9\uac00\uc9c0\ud45c\ub97c \ubaa8\ub450 \ucda9\uc871\ud588\ub2e4\uace0 \ubc1c\ud45c\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

                  ASCO\uc5d0\uc11c \uc0c8\ub85c \ubc1c\ud45c\ub41c \ub0b4\uc6a9:<\/strong>\u00a0\ub178\ubc14\ud2f0\uc2a4\ub294 VISION \uc5f0\uad6c\uc5d0\uc11c PSMA \ud45c\uc801 \ubc29\uc0ac\uc131 \ub9ac\uac04\ub4dc \uce58\ub8cc\uc81c(radioligand therapy)\uc778 177<\/sup>Lu-PSMA-617\uc758 \ucd5c\ucd08 \ub370\uc774\ud130<\/a>\ub97c \uacf5\uac1c\ud588\uc2b5\ub2c8\ub2e4. VISION \uc5f0\uad6c\ub294 \ucd5c\uc18c \ud55c\uac00\uc9c0\uc758 \ud0c1\uc0b0(taxane) \uc694\ubc95\uacfc 2\uc138\ub300 \ud638\ub974\ubaac \uce58\ub8cc\ub97c \ubc1b\uc740 \uc801\uc774 \uc788\ub294 \uc9c4\ud589\uc131 PSMA \uc591\uc131 mCRPC (PSMA-positive metastatic castration-resistant prostate cancer) \ud658\uc790\ub97c \ub300\uc0c1\uc73c\ub85c \ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ubc29\uc0ac\uc131 \ub9ac\uac04\ub4dc\ub97c \uc774\uc6a9\ud55c \uce58\ub8cc\ub294 \ud45c\uc900 \uce58\ub8cc\uc640 \ube44\uad50\ud558\uc5ec 38%\uc758 \uc0ac\ub9dd\uc704\ud5d8 \uac10\uc18c\uc640 \ud568\uaed8 \ud1b5\uacc4\uc801\uc73c\ub85c \ub9e4\uc6b0 \uc720\uc758\ubbf8\ud55c \uc804\uccb4 \uc0dd\uc874\uae30\uac04(OS)\uc758 \uac1c\uc120\uc744 \ubcf4\uc600\uc2b5\ub2c8\ub2e4 (p <0.001).<\/p>\n

                  \uc804\ub9dd<\/strong>:<\/strong>\u00a0 177<\/sup>Lu-PSMA-617\uc740 \uc0c8\ub85c\uc6b4 \uc791\uc6a9 \uae30\uc804\uc744 \uc81c\uc2dc\ud558\uc600\uace0, \uce58\ub8cc \uc774\ub825\uc774 \ub9ce\uc740 \ud558\uc704 \ud658\uc790\uad70\uc758 \ub300\uccb4 \uce58\ub8cc\uc635\uc158\uc5d0 \ub300\ud55c \ub192\uc740 \ubbf8\ucda9\uc871 \uc218\uc694 \ub54c\ubb38\uc5d0 PSMA \ud45c\uc801 \uc694\ubc95\uc5d0 \ub300\ud55c \uae30\ub300\uac10\uc744 \ubd88\ub7ec \uc77c\uc73c\ud0a4\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc911\uc694\ud55c \uac83\uc740, \uc9c4\ud589\uc131 \uc804\ub9bd\uc120\uc554(advanced prostate cancer)\uc5d0\uc11c PSMA\uc758 \ub192\uc740 \ubc1c\ud604 \uc218\uc900\uc744 \uace0\ub824\ud560 \ub54c 177<\/sup>Lu-PSMA-617\uc740 \uc7a0\uc7ac\uc801\uc73c\ub85c \ud070 \uaddc\ubaa8\uc758 \ud658\uc790 \uc9d1\ub2e8\uc744 \ub300\uc0c1\uc73c\ub85c \ud55c\ub2e4\ub294 \uac83\uc785\ub2c8\ub2e4. \u00a0\uadf8\ub7ec\ub098 \ubc29\uc0ac\uc131\uc758\uc57d\ud488\uc758 \uce58\ub8cc\uc640 \uc758\ub8b0 \uacbd\ub85c\uc5d0 \ub300\ud55c \uc8fc\uc694 \uace0\ub824 \uc0ac\ud56d\uc774 \ub0a8\uc544 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc0ac\ud56d\ub4e4\uc740 \ub300\uccb4\uc801\uc73c\ub85c \uaf64\ub098 \ubcf5\uc7a1\ud558\uace0, \uc5ed\uc0ac\uc801\uc73c\ub85c\ub3c4 \uc774\ub7ec\ud55c \uce58\ub8cc\ubc95\uc740 \ud604\uc2e4\uc5d0\uc11c\ub294 \uc81c\ud55c\uc801\uc73c\ub85c\ub9cc \ucc44\ud0dd\ub418\uc5b4 \uc654\uc2b5\ub2c8\ub2e4.<\/p>\n

                   <\/p>\n

                   <\/p>\n

                  \uc62c\ud574\uc758 \uc5f0\ub840\ud559\uc220\ub300\ud68c\uc5d0\uc11c\ub294 \uc9c8\ubcd1\uc758 \ucd08\uae30 \ub2e8\uacc4 \uce58\ub8cc\ub97c \uc704\ud55c \ud45c\uc801 \uc694\ubc95\uc758 \ubc1c\uc804\uc744 \ud3ec\ud568\ud558\uc5ec \ud765\ubbf8\ub85c\uc6b4 \ucd94\uc138\uac00 \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc5f0\ub840\ud559\uc220\ub300\ud68c \uc8fc\uc694 \ub370\uc774\ud130\uc5d0 \ub300\ud55c \uc2ec\uce35 \ubd84\uc11d\uc740 \ub2f9\uc0ac \uc804\ubb38\uac00\ud300\uc758 \ud6c4\uc18d \uae30\uc0ac\uc5d0\uc11c \ud655\uc778\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

                  \uc774 \uae30\uc0ac\uc5d0 \uae30\uc5ec\ud55c \ud074\ub798\ub9ac\ubca0\uc774\ud2b8 \uc885\uc591\ud559 \uc804\ubb38\uac00\ub4e4\uc740 \ub2e4\uc74c\uacfc \uac19\uc2b5\ub2c8\ub2e4. \uc544\ub974\ub9cc \uc5d0\uc2a4\ud310\ub514\uc544\ub9ac(Arman Esfandiari). \uce90\ub864\ub9ac\ub098 \ub3c4 \ud30c\uc870(Carolina do Pazo), \ud53c\uc624\ub098 \uc704\uac70\ud2b8(Fiona Wiegert), \uadf8\ub808\uc774\uc2a4 \ubc0b\uccbc(Grace Mitchell), \ub85c\ub77c \ube44\ub204\uc5d0\uc0ac(Laura Vinuesa), \ub9ac\uc138\uc2a4 \ud30c\ub77c(Liseth Parra), \ud504\ub9ac\uc580\uce74 \uba54\ub77c(Priyanka Mehra), \uc0ac\uc774\ub4dc\ud558 \uad7d\ud0c0(Snigdha Gupta), \uc18c\ub974\ucc28 \uce90\uc2dc\ub514(Sorcha Cassidy), \uc544\ub098\ubbf8\uce74 \uace0\uc26c(Anamika Ghosh), \ucfe0\ub78c \ub098\uc640\uc988(Khurram Nawaz) \uadf8\ub9ac\uace0 \ub808\uc774\uccbc \uc6f9\uc2a4\ud130(Rachel Webster).<\/em><\/p>\n

                  \ube60\ub974\uac8c \ubcc0\ud654\ud558\ub294 \uc885\uc591\ud559 \uc2dc\uc7a5\uc5d0\uc11c \ucd5c\uc2e0 \uc815\ubcf4\ub97c \ud30c\uc545\ud558\uc5ec \uc120\ub450\ub97c \uc720\uc9c0\ud558\uace0 \ub370\uc774\ud130\uc5d0 \uae30\ubc18\ud55c \uc758\uc0ac \uacb0\uc815\uc744 \ub0b4\ub9ac\uc138\uc694. \ud074\ub798\ub9ac\ubca0\uc774\ud2b8\uc758 \ud3ec\ud2b8\ud3f4\ub9ac\uc624 \uc804\ub7b5 \ubc0f \ube44\uc988\ub2c8\uc2a4 \uac1c\ubc1c \uc194\ub8e8\uc158<\/a>\uc5d0 \ub300\ud574 \uc790\uc138\ud788 \uc54c\uc544\ubcf4\uc138\uc694.<\/p>\n

                   <\/p>\n

                   <\/p>\n","protected":false},"excerpt":{"rendered":"

                  ASCO 2021 \uc885\uc591\ud559 10\ub300 \uc774\uc288 \ud074\ub798\ub9ac\ubca0\uc774\ud2b8\uc758 \uc885\uc591\ud559 \uc804\ubb38\uac00\ub4e4\uc740 \ubbf8\uad6d\uc784\uc0c1\uc885\uc591\ud559\ud68c(ASCO)\uc5d0\uc11c \ubc1c\ud45c\ub41c 2,400\uac1c \uc774\uc0c1\uc758 \ucd08\ub85d\uc744 \ubd84\uc11d\ud558\uc5ec \uc57d\ubb3c \uce58\ub8cc \ub3d9\ud5a5\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc0c1\uc704 \uc5f0\uad6c 10\uac74\uc744 \uc120\uc815\ud588\uc2b5\ub2c8\ub2e4. \uc774 \uae30\uc0ac\ub294 \ub17c\ubb38\uc744 \ud1b5\ud574 \ubc1c\uacac\ud55c \ud765\ubbf8\ub85c\uc6b4 \uc0ac\uc2e4\uacfc…<\/p>\n","protected":false},"author":208,"featured_media":2163,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_links_to":"","_links_to_type":0,"footnotes":""},"categories":[1315],"tags":[],"class_list":["post-2206","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-life-sciences-healthcare","clarivate-industry-life-sciences-and-healthcare","clarivate-product-biopharma"],"acf":[],"lang":"ko","translations":{"ko":2206},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"pll_sync_post":[],"_links":{"self":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/posts\/2206","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/users\/208"}],"replies":[{"embeddable":true,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/comments?post=2206"}],"version-history":[{"count":0,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/posts\/2206\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/media\/2163"}],"wp:attachment":[{"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/media?parent=2206"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/categories?post=2206"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/clarivate.com\/life-sciences-healthcare\/wp-json\/wp\/v2\/tags?post=2206"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}