IP-GeoScape® offers a visual landscape of the molecular IP space that reveals the multi-dimensional relationship between molecules within a target area of interest. Designed for the way medicinal chemists, legal professionals and BD&L professionals think, IP-GeoScape is used to guide strategic decision-making across R&D, patenting and licensing.
K-Ras is a GTPase and a part of the RAS/MAPK pathway. This protein helps to relay vital proliferation signals that come from outside the cell, into the nucleus. This makes K-Ras a very important target for oncology. This importance is enhanced due to activating mutations which are implicated in several malignancies. It is also a very ‘hot’ target with patent families increasing by 45%, and assignees by 57%, over the last two quarters.
A. The landscape tab does not have axes, instead the relative distance of one molecule to another is used to indicate relative molecular structural similarity. Similar molecules are clustered together, and similar clusters are close to each other. Therefore, the more similar a molecule is to another the closer they appear on the landscape, with very different molecules positioned far apart.
A. All IP-GeoScapes contain exemplified molecules from the relevant patents. We specifically include only exemplified molecules because, while the complete genus could be enumerated and mapped, our analysis has shown that the results are unwieldy and no more useful than exemplified only. The exemplified molecules are a representative sample of the genus and will, ultimately, delimit the granted claims.
A. While we strive for 100% of all exemplified molecules for the relevant patents, some structures are unextractable. However, we always ensure that a sufficient percentage of the exemplified molecules for the relevant patents are featured so users are able to gain the key intelligence they need to do their work.
A. Of course! We are adding new IP-GeoScapes associated with new biological targets all the time, but we always welcome suggestions as to new targets to focus on. So if we don’t list something you’re interested in, get in touch and we will work with you to get it added as soon as possible.
A. IP-GeoScape is designed for the way medicinal chemists think and work, facilitating more efficient and effective new molecule discovery. The Landscape tab reveals areas not currently being explored through analysis of, and substructure searching within, the occupied and unoccupied IP space, whilst also showing how molecular IP associated with a target has developed over time, and where competitors are currently active.
The MedChem tab provides a view intended to be specifically useful for molecular design. It provides a simplified, tiled representation of the molecular IP landscape arranged by structural similarity. Each tile, when selected, gives a simple, but powerful, representation of the contents of the cluster by displaying an image of the most representative structure from the cluster with the most common substructure within the cluster highlighted. This tiled view clearly reveals the unoccupied space which are ripe for new molecules, and by selecting the tiles surrounding such spaces, users can see how the chemotypes on opposite sides of the unoccupied space can be merged to create new compounds.
A. IP-GeoScape is designed for the way legal, business development, licensing and/or patent informatics professionals think and work, delivering actionable IP intelligence in a uniquely visual way. The Landscape tab enables users to see and understand the competitive space associated with a biological target including where competitors are particularly active, and how the molecular IP has developed over time. The Competitive Overview tab then breaks the data down on the basis of who, what, and when- presenting the data by assignee and priority year, revealing at-a-glance which assignees were active when and enabling in depth review of the patents themselves.
The Analysis tab is designed to be primarily used by IP and business development professionals, revealing overlaps in the IP. This overlap information is very useful for IP professionals to scan for potential interference. Not all overlaps mean interference, but they can alert you to the risk. This view is also useful for licensing professionals seeking partnerships or other deals as overlaps in the most recent IP can be indicative of areas of mutual interest. In fact, this precise type of analysis has been successfully used to find both interference and to establish joint ventures in specific areas.
A. We offer a range of additional scientific, commercial and other data to enhance your IP-GeoScape. We can also add private/unpublished data and molecules, as well as offering additional support, analysis and consulting. Just get in touch to find out how we can help.
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