On-demand Webinar

New Systems Biology analysis methods

Characterize TB immune and treatment responses

Alexey Dubovenko
Discovery Solutions Product Manager
Clarivate Analytics
Tuberculosis (TB) infection significantly affects the human immune system. This, however, provides an opportunity to study the immune system modulation to identify markers especially for latent phase and non-lung infection. Additionally, changes in the host immune response could be sensitive indicators of mycobacterial killing by treatment and might give insight into the immune dysregulation in TB patients reflecting therapy response. Among the methods used in TB research a new combination of gene expression profiling and systems biology analysis has recently been utilized for the biomarker research and therapy progression analysis.
In this webinar we are going to discuss how high-throughput experimental approach and pathway analysis can be complemented with associated long-term clinical annotation comprising drug response and expression changes in patients based on recent scientific publications.
This webinar will help you:
  • Learn how systems biology methods could be utilized to leverage Tuberculosis research in partly understood areas based on recent scientific publications.
  • Review novel molecular biomarker discovery for latent and active TB differentiation.
  • Explore gene expression signatures identification of TB heterogeneity and treatment response prediction.