Life Sciences and Healthcare

Roche’s Ocrevus to dominate the multiple sclerosis market

As it enters the market, Ocrevus (ocrelizumab) is a drug set not only to top the multiple sclerosis (MS) field, but also to be 2017’s biggest future-blockbuster entrant. The 2017 edition of the annual Drugs to Watch report forecasts that seven new drugs including Ocrevus will enter the market in 2017 and achieve blockbuster sales of more than 1 billion by 2021, as evaluated by consensus sales forecast data from Clarivate Analytics Cortellis Competitive Intelligence (source Thomson Reuters I/B/E/S).

The 3 Rs of cancer research: rigor, reproducibility and robustness

As scientists gathered at the 2017 meeting of the American Association for Cancer Research (AACR) in Washington in early April to learn about the latest advances in cancer research, one of the questions was how much of that research would hold up to attempts to reproduce it.

Health technology gadgets – good, bad or transformative?

Digital innovations and their adoption, specifically health related gadgets, could indicate a shift to consumers becoming the key opinion leaders of their own healthcare. Is a big change coming? Personally I love tech and can easily be absorbed by a new development idea that challenges the tech of yesterday. I remember, many years ago now, […]

New drug development: finding the balance between quality and quantity

Much has been said about the precipitous drop in FDA approvals during 2016, and in fact retiring FDA new drugs director John Jenkins reported in December that as of Dec. 9, 2016, the U.S. agency had approved just 19 NDAs and BLAs, the lowest number since 2007 (Fig. 1). By year-end, that number had increased […]

Outcomes-Based Contracting Gain Steam

Amgen’s recent offer to refund to health plans the cost of its statin add-on therapy Repatha for eligible patients who take it and then suffer a heart attack or stroke highlights the extent pharmaceutical companies are willing to go to overcome insurance access barriers to expensive, groundbreaking therapies. The refund offer was announced along with […]

ACC.17: a roller coaster of results

ACC is done for another year, with a multitude of exciting trials presented, including FOURIER, EBBINGHAUS, SPIRE-1 and -2, ORION-1, and CARAT. There were negative as well as positive results, making for a very interesting meeting and some important scientific breakthroughs. Let’s start with the positive. The results from FOURIER, the cardiovascular outcomes trial for […]