Life Sciences and Healthcare

ASCO 2019: The future of Keytruda plus chemo combination therapy

Checkpoint inhibitor combination strategies remains a focus of development, but chemo combos are not a slam dunk for every indication. As the 40,000 attendees of this year’s ASCO conference relinquish their hold of the windy city, oncology experts worldwide begin contemplating the wealth of new or expanded data which was presented, and how it might […]

Biopharma mega mergers remain a force: Q1 analysis

During the first  quarter of 2019, Cortellis Deals Intelligence registered 124 new mergers and acquisitions (M&A), a 24% increase from 100, quarter on quarter vs. last year, as part of its ongoing coverage of M&A activity in the life sciences sector (see Figure 1). However, total disclosed deal value declined by 9% to $119.2 billion […]

Will Netflix-Style Payment Models be the New Norm For High Cost Drugs?

With specialty drug prices increasing each day, states are challenged to manage costs while patients face cost barriers to drug access, which negatively impacts adherence and cure rates. Hepatitis C, for example, is a costly disease impacting tens of thousands of people in the United States, which has historically struggled with a track record of […]

2018 regulatory approvals tackling unmet medical needs

Major improvements in the regulatory environment as well as changes in strategies of multinational companies have led to a general decrease in the time to marketing authorization, improved consistency, as well as an increase in the number of medicines that have become available over the last decade, 2009-2018, across six major regulatory agencies. These are […]

The Changing Specialty Drug Reimbursement Landscape

Advancements in medicine have led to the development of new specialty drugs treating a greater number of rare conditions. In the early 1990s, specialty drugs were limited to a small number of populations, with only 30 drugs available in the market. Presently, more than 400 specialty drugs are available and the developing drug pipelines indicate […]

Breast Cancer: A Model Indication for Personalized Medicine

The Heterogeneity of Breast Cancer Since its conception almost two decades ago, the strategy to base treatment selection on HR- and HER2-status has stood the test of time. Based on the expression characteristics of breast cancer, hormonal agents and HER2-targeting agents have been successfully exploited. However, in recent years, novel biomarker-driven agents have been approved […]

Building A Market Access Advantage During Early Stage Development

How can pharma companies build market access advantage during early stage development? The market access environment in the US has become tougher than ever for innovative pharma companies with payers and policy makers increasingly scrutinizing the drug prices and demanding cost-effectiveness data to justify the heavy price tags. Therefore, it is of vital importance for […]

Medtronic drives innovation, eyeing new products to stay on top

BioWorld MedTech™, the global medical device news service from Clarivate Analytics, developed a series of articles on how key companies in the industry approach innovation. Below is an excerpt from the profile of Medtronic plc. Click here to access to the full series. Medtronic plc is the largest pure-play med-tech company in the world by […]

Growing Patient Involvement in Health Technology Assessment (HTA)

Health technology assessment (HTA) agencies such as National Institute for Health and Care Excellence (NICE – UK), Scottish Medicines Consortium (SMC – Scotland), Pharmaceutical Benefits Advisory Committee (PBAC – Australia) and Pan-Canadian Oncology Drug Review (pCODR – Canada) have been at the forefront of incorporating user input and feedback in drug reviews. Patient and caregiver […]

Proven methods to improve door-to-needle times for stroke patients

Accounting for about 133,000 deaths per year, stroke ranks fifth among all causes of death in the United States, according to the American Heart Association. This life-threatening condition occurs irrespective of age and can lead to serious long-term disabilities. With May being recognized as National Stroke Awareness month, it serves as a reminder to hospitals and […]